#475 Q&A: Biggest things that contribute to my health, does caffeine age the brain, can you make up for lost sleep and more

Get Bon Charge red light therapy for 15% off: https://boncharge.com/pages/siimlandTimestamps: 00:38 Nick’s PhD and autophagy research 02:33 What is autophagy 03:53 Autophagy and longevity 08:05 Bon Charge Sponsorship 08:55 Where autophagy comes from 11:40 What triggers autophagy 18:15 mTOR and longevity 20:15 Should you eat a lower protein diet 25:45 Supplements for autophagy 28:35 Metformin 32:35 Acarbose 34:25 Rapamycin 36:35 Speed of aging tests 43:00 Longevity supplements 50:05 Nick’s opinions on diet 56:35 Nick’s nutrition, exercise and supplement plan 01:01:10 Importance of sleepPhysionic YouTube channel: https://www.youtube.com/@Physionic/

7 Mar 1h 7min

BioPrime oral BPC157 with code SIIM10 for 10% discount - Get 3 month supply for best effects: https://www.bioprimesupplements.com/index.php?route=product%2Fproduct&product_id=53&tracking=g8PrbVPWwr3K1a42mbbnslSqmty6fFgjT3YxDU0MAXwf18eL4MBMHgSQgFBSv3FrTimestamps:00:25 Dr Karli’s training in cell therapies07:00 BioPrime Supplements Sponsorship07:55 Why do people develop pain disorders10:00 Importance of exercise for orthopedic longevity14:30 Injuries from exercise19:30 Does nutrition play a role in joint disorders23:40 Stem cells for orthopedics35:30 Converging functional medicine and regenerative medicine42:05 When do you need surgery44:25 PRP – platelet rich plasma48:10 PRP and stem cells for prevention54:10 Peptides for joints59:40 Rapid fire round: which joint problem which therapy 01:07:40 Daily exercises to prevent joint painDr David Karli Instagram: https://www.instagram.com/davidkarli/

26 Feb 1h 12min

Get Bon Charge red light therapy for 15% off: https://boncharge.com/pages/siimlandTimestamps: 00:41 Mark’s backstory 05:41 How the body and mind connected 11:40 How to balance your nervous system 20:30 How to stimulate the vagus nerve 23:10 Nutrition and gut health 27:10 Blood markers for stress 30:00 You need to focus on both mental and physical health 40:20 How to deal with health anxiety 46:30 Mark’s free webinar 49:35 Core pillars of thriving as a humanDr Mark's Free Webinar Thrive Essentials: https://theschoolofbiohacking.com/programs/thrive-essentials/ref/5/

22 Feb 58min

Timestamps: 00:00 Introduction 01:40 How Tyler Got Into Genetics 07:00 How Genes Affect Caffeine Metabolism 14:35 Creatine and Genetics 22:40 Citrulline and Arginine 27:35 Glycine 32:35 Histamine, Fermented Foods, Bone Broth 37:20 Food Sensitivities and Plant Chemicals 41:00 Methylation 44:05 Microplastics 48:40 Melatonin 54:30 Vitamin D 59:55 Omega-3s 01:04:40 Where to Start Understanding Your Genetics 01:08:30 Food Allergy TestingDr Tyler Panzner Instagram: https://www.instagram.com/drtylerpanzner/Dr Tyler Panzner website: https://drtylerpanzner.com/

15 Feb 1h 10min

Get Olli's and My Longevity Books (Code SIIMLAND for a 15% discount): https://biohackercenter.com/collections/books-longevity-biohackingTimestamps:00:18 Overlap Between Resilience and Longevity09:48 Hormesis and Adaptation14:48 Voluntarily Exposing Yourself to Stress20:18 Sauna Benefits32:43 Contrast Therapy with Sauna and Cold34:08 Benefits of Cold Exposure43:23 How to Track Your Response to Stress49:23 Vagus Nerve and Nervous System57:13 Exercise and Stress Resilience01:03:08 Olli’s Top 3 Adaptogens01:13:08 Plant Defense ChemicalsOlli Sovijärvi Instagram: https://www.instagram.com/ollisovijarvi/

9 Feb 1h 28min

Order my new book: https://www.amazon.com/dp/B0CW1B2XM1 Timestamps: 00:00 Intro 00:21 Why Nathan Dropped Out of His PhD Thesis to Pursue Longevity Research 07:51 Roadmap to Extending Human Lifespan 12:41 Body Replacement 18:33 Organ Cloning 26:11 Brain Replacement 33:36 Cyborg Organs 36:38 Pausing Aging in the Body 45:58 Bioengineering and Gene Therapy 56:36 Vitalism Nathan Cheng X: https://x.com/realNathanCheng

1 Feb 1h 20min

Get Bon Charge infrared sauna blanket 15% off: https://boncharge.com/pages/siimland Timestamps: 00:00 Intro 00:30 Why Skin Anti-Aging Matters 02:15 What Everyone Should Do for Skin Anti-Aging 06:25 Bon Charge Sponsorship 07:12 Skin Aging Analysis Techniques 12:15 Pores and Cleaning the Skin 15:25 Three Basic Products Alexis Gives His Patients 20:55 Best Sunscreens to Take 37:30 Retinol 48:15 Microneedling 53:05 Red Light Therapy and Lasers 01:02:35 Botox 01:08:35 Exosomes 01:14:15 Moisturizers 01:17:40 Copper Peptide GHK-Cu 01:23:00 Niacinamide 01:24:55 Skin anti-aging supplements 01:34:55 Final words Alexis Ortega MD Instagram: https://www.instagram.com/alexis_ortega_md/

1 Feb 1h 37min

Get Bon Charge infrared sauna blanket 15% off: https://boncharge.com/pages/siimland Timestamps: 00:00 Introduction 00:30 What Is Methylene Blue 05:35 Methylene Blue Antiviral Effects 12:55 Methylene Blue Effects on Mitochondrial Function 17:55 Is Methylene Blue and Oxygen 24:30 Methylene Blue for Exercise 26:10 Nitric Oxide 31:25 Does Methylene Blue Have Longevity Benefits 39:50 Skin Anti-Aging Effects 43:30 Safety 48:50 Nootropic Effects 52:05 Right Dosage Dr Scott Sherr Instagram: https://www.instagram.com/drscottsherr/

18 Jan 59min