GLP-1: A breakthrough for diabetes and obesity
Witness History23 Okt 2025

GLP-1: A breakthrough for diabetes and obesity

In the 1980s, scientists made a discovery that would eventually lead to the development of drugs now used worldwide to treat diabetes and to help people manage obesity through weight loss injections.

One of the key scientists behind this breakthrough was Svetlana Mojsov. She discovered that a hormone called GLP-1 (glucagon-like peptide-1) plays an important role in how our bodies respond to food.

Svetlana’s work laid the foundation for a drug company to develop treatments based on GLP-1 — first for type 2 diabetes, and later for weight loss. She tells Gill Kearsley her story.

Eye-witness accounts brought to life by archive. Witness History is for those fascinated by the past. We take you to the events that have shaped our world through the eyes of the people who were there. For nine minutes every day, we take you back in time and all over the world, to examine wars, coups, scientific discoveries, cultural moments and much more. Recent episodes explore everything from the death of Adolf Hitler, the first spacewalk and the making of the movie Jaws, to celebrity tortoise Lonesome George, the Kobe earthquake and the invention of superglue. We look at the lives of some of the most famous leaders, artists, scientists and personalities in history, including: Eva Peron – Argentina’s Evita; President Ronald Reagan and his famous ‘tear down this wall’ speech; Thomas Keneally on why he wrote Schindler’s List; and Jacques Derrida, France’s ‘rock star’ philosopher. You can learn all about fascinating and surprising stories, such as the civil rights swimming protest; the disastrous D-Day rehearsal; and the death of one of the world’s oldest languages.

(Photo: Injection pens. Credit: Carsten Snejbjerg/Bloomberg via Getty Images)

Episoder(2000)

World War Two’s Shetland Bus

World War Two’s Shetland Bus

During World War Two, whilst Norway was occupied by Nazi Germany, a group of Norwegian sailors set up a base on the Shetland Islands and began aiding their country’s resistance. Named “The Shetland B...

16 Feb 10min

The flooding of Florence

The flooding of Florence

In November, 1966, Florence suffered one of the worst floods in its history after heavy rainfall caused the River Arno to burst.The Italian city was submerged under tons of mud, rubble and sewage, lea...

13 Feb 10min

The Mont Blanc Tunnel

The Mont Blanc Tunnel

In July 1965, a 12km tunnel dug deep beneath the Alps was opened to traffic, making it the longest vehicular tunnel in the world. Linking France and Italy, the Mont Blanc Tunnel was a remarkable feat ...

12 Feb 9min

Gina Lollobrigida interviews Fidel Castro

Gina Lollobrigida interviews Fidel Castro

Gina Lollobrigida was one of the biggest stars of European cinema in the 1950s and 1960s. Often described as "the most beautiful woman in the world", her films included Beat the Devil, the Hunchback o...

11 Feb 10min

When Pink Floyd played in Venice

When Pink Floyd played in Venice

In July 1989, Pink Floyd played a free concert to 200,000 people in Venice, Italy. The British rock band took to a stage made of floating barges as crowds of fans watched from boats, gondolas and roof...

10 Feb 10min

The discovery of nerve growth factor

The discovery of nerve growth factor

During World War Two, Italian scientist Dr Rita Levi-Montalcini was forced to do experiments in her bedroom after being banned from universities because she was Jewish. Her experiments in that bedro...

9 Feb 10min

My dad created Mr Men and Little Miss

My dad created Mr Men and Little Miss

In 1971, advertising writer Roger Hargreaves's eight-year-old son Adam asked him an unusual question: 'What does a tickle look like?'Inspired, Roger got out his marker pens and created an orange chara...

6 Feb 10min

Austria's wine scandal

Austria's wine scandal

In 1985, government scientists discovered anti-freeze in bottles of fine Austrian wine. No one died or fell ill from drinking the poisoned wine, but the scandal nearly destroyed the country's wine-mak...

5 Feb 10min

Populært innen Samfunn

rss-spartsklubben
giver-og-gjengen-vg
aftenpodden
konspirasjonspodden
aftenpodden-usa
popradet
lydartikler-fra-aftenposten
rss-nesten-hele-uka-med-lepperod
rss-henlagt-andy-larsgaard
wolfgang-wee-uncut
grenselos
min-barneoppdragelse
alt-fortalt
synnve-og-vanessa
rss-dette-ma-aldri-skje-igjen
frokostshowet-pa-p5
rss-dannet-uten-piano
fladseth
rss-frekvens-med-anine-olsen
198-land-med-einar-trnquist