Immune

Immune

A podcast about the body's defenders against disease.

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Episoder(139)

Immune 27: Trained immunity

Immune 27: Trained immunity

Steph explains how sepsis induces protective immune memory in NK cells, via histone methylation of the interferon gamma enhancer. Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer Subscr...

11 Jan 20201h 33min

Immune 26: Measles erases immune memory

Immune 26: Measles erases immune memory

Michael Mina joins the Immune team to explain his findings that measles diminishes pre-existing antibodies that protect against infection with other pathogens. Hosts: Vincent Racaniello, Stephanie Lan...

28 Nov 20191h 37min

Immune 25: Remembrance of antigen encounters past

Immune 25: Remembrance of antigen encounters past

The Immune team explains that short chain fatty acids produced by microbial fermentation of fiber rewire metabolism to enable the production of memory T cells. Hosts: Vincent Racaniello, Stephanie Lan...

1 Nov 20191h 22min

Immune 24: Unlucky IL-13

Immune 24: Unlucky IL-13

The Immune team reveals a new type of T helper cell that drives the production of IgE, leading to allergic responses. Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer Subscribe (free): ...

19 Sep 20191h 29min

Immune 23: How to tell a mouse from a mouse

Immune 23: How to tell a mouse from a mouse

The immunosomes explain that widely used inbred laboratory mice are not identical, and how to tell them apart. Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer Subscribe (free): iTunes,...

14 Aug 20191h 27min

Immune 22: Engineering B cells

Immune 22: Engineering B cells

Immune reveals an alternative to a protective vaccine, engineered B cells that produce antiviral antibodies. Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer Subscribe (free): iTunes, G...

31 Jul 20191h 18min

Immune 21: Islets of Langelhans

Immune 21: Islets of Langelhans

Immune tackles the finding that patients with Type I diabetes have lymphocytes with both TCR and BCR that may drive the pathogenesis of the disease. Hosts: Vincent Racaniello, Stephanie Langel, and Cy...

12 Jun 20191h 27min

Immune 20: In defense of death

Immune 20: In defense of death

The Immune trio explains how activation of the inflammasome by a bacterial protein causes blood clotting through a programmed cell death process called pyroptosis.   Subscribe (free): iTunes, Google P...

29 Mai 20191h 28min

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