The a16z Show
The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

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Episoder(1000)

Healthcare 2026: AI Doctors, GLP-1s, and Insurance Defection

Healthcare 2026: AI Doctors, GLP-1s, and Insurance Defection

Out-of-Pocket is a healthcare education company founded by Nikhil Krishnan that helps people understand how healthcare works and how to navigate it in practice. In this episode, a16z investing partner...

27 Jan 1h 34min

The Hidden Economics Powering AI

The Hidden Economics Powering AI

In this episode, Jen Kha, Head of Investor Relations, and David George, General Partner, discuss how late-stage private markets are evolving as AI reshapes scale, capital intensity, and growth timelin...

26 Jan 1h 4min

How Mintlify Is Rebuilding Documentation for Coding Agents

How Mintlify Is Rebuilding Documentation for Coding Agents

Mintlify is a documentation platform built by cofounders Han Wang and Hahnbee Lee to help teams create and maintain developer docs. In this episode, Andreessen Horowitz general partners Jennifer Li an...

23 Jan 44min

Inferact: Building the Infrastructure That Runs Modern AI

Inferact: Building the Infrastructure That Runs Modern AI

Inferact is a new AI infrastructure company founded by the creators and core maintainers of vLLM. Its mission is to build a universal, open-source inference layer that makes large AI models faster, ch...

22 Jan 43min

Martin Casado on the Demand Forces Behind AI

Martin Casado on the Demand Forces Behind AI

In this feed drop from The Six Five Pod, a16z General Partner Martin Casado discusses how AI is changing infrastructure, software, and enterprise purchasing. He explains why current constraints are dr...

21 Jan 27min

From Code Search to AI Agents: Inside Sourcegraph's Transformation with CTO Beyang Liu

From Code Search to AI Agents: Inside Sourcegraph's Transformation with CTO Beyang Liu

Sourcegraph's CTO just revealed why 90% of his code now comes from agents—and why the Chinese models powering America's AI future should terrify Washington. While Silicon Valley obsesses over AGI apoc...

20 Jan 46min

The AI Opportunity That Goes Beyond Models

The AI Opportunity That Goes Beyond Models

The a16z AI Apps team outlines how they are thinking about the AI application cycle and why they believe it represents the largest and fastest product shift in software to date. The conversation place...

19 Jan 1h 10min

How Foundation Models Evolved: A PhD Journey Through AI's Breakthrough Era

How Foundation Models Evolved: A PhD Journey Through AI's Breakthrough Era

The Stanford PhD who built DSPy thought he was just creating better prompts—until he realized he'd accidentally invented a new paradigm that makes LLMs actually programmable. While everyone obsesses o...

16 Jan 57min

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