How OpenAI Builds for 800 Million Weekly Users: Model Specialization and Fine-Tuning
The a16z Show28 Nov 2025

How OpenAI Builds for 800 Million Weekly Users: Model Specialization and Fine-Tuning

In this episode, a16z GP Martin Casado sits down with Sherwin Wu, Head of Engineering for the OpenAI Platform, to break down how OpenAI organizes its platform across models, pricing, and infrastructure, and how it is shifting from a single general-purpose model to a portfolio of specialized systems, custom fine-tuning options, and node-based agent workflows.

They get into why developers tend to stick with a trusted model family, what builds that trust, and why the industry moved past the idea of one model that can do everything. Sherwin also explains the evolution from prompt engineering to context design and how companies use OpenAI’s fine-tuning and RFT APIs to shape model behavior with their own data.

Highlights from the conversation include:

• How OpenAI balances a horizontal API platform with vertical products like ChatGPT
• The evolution from Codex to the Composer model
• Why usage-based pricing works and where outcome-based pricing breaks
• What the Harmonic Labs and Rockset acquisitions added to OpenAI’s agent work
• Why the new agent builder is deterministic, node based, and not free roaming

Resources:

Follow Sherwin on X: https://x.com/sherwinwu

Follow Martin on X: https://x.com/martin_casado

Stay Updated:

If you enjoyed this episode, be sure to like, subscribe, and share with your friends!

Find a16z on X: https://x.com/a16z

Find a16z on LinkedIn: https://www.linkedin.com/company/a16z

Listen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYX

Listen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711

Follow our host: https://x.com/eriktorenberg

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see http://a16z.com/disclosures

Stay Updated:

Find a16z on YouTube: YouTube

Find a16z on X

Find a16z on LinkedIn

Listen to the a16z Show on Spotify

Listen to the a16z Show on Apple Podcasts

Follow our host: https://twitter.com/eriktorenberg

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.


Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Avsnitt(1000)

Balaji and Dan Wang: The Engineering State vs Lawyerly State

Balaji and Dan Wang: The Engineering State vs Lawyerly State

Balaji Srinivasan speaks with Dan Wang, author of Breakneck, about China's industrial rise, America's competing strengths in software and finance, and what happens when an engineering state and a lawy...

13 Feb 1h 3min

Anish Acharya: Is SaaS Dead in a World of AI?

Anish Acharya: Is SaaS Dead in a World of AI?

In this episode from 20VC, Harry Stebbings talks with Anish Acharya, general partner at a16z, about the future of SaaS in an AI world. Anish argues that software is completely oversold and that the ge...

12 Feb 1h 21min

How Magic Johnson Built a Billion-Dollar Portfolio in 30 Years

How Magic Johnson Built a Billion-Dollar Portfolio in 30 Years

a16z’s Chris Lyons speaks with Earvin "Magic" Johnson about his 30-year journey from athlete to billionaire businessman. They cover the art of deal-making, lessons from mentors Michael Ovitz and Dr. J...

11 Feb 1h 5min

Marc Andreessen: Who Runs the World’s AI?

Marc Andreessen: Who Runs the World’s AI?

Cisco president and CPO Jeetu Patel speaks with a16z cofounder Marc Andreessen about why AI may finally break a 50-year productivity slump—and what's at stake if America doesn't win the race. They dis...

10 Feb 26min

The State of Markets

The State of Markets

a16z Head of Investor Relations Jen Kha speaks with general partner David George about the state of AI and private technology markets. David shares data on why AI companies are growing 2.5x faster tha...

9 Feb 47min

Balaji & Benedict Evans: When Tech Breaks Industries

Balaji & Benedict Evans: When Tech Breaks Industries

This episode originally appeared on the Network State Podcast. Balaji Srinivasan and Benedict Evans sit down in Singapore for a wide-ranging conversation on the mechanics of disruption. Evans, a forme...

6 Feb 2h 6min

Why This Isn't the Dot-Com Bubble | Martin Casado on WSJ's BOLD NAMES

Why This Isn't the Dot-Com Bubble | Martin Casado on WSJ's BOLD NAMES

Christopher Mims and Tim Higgins of the Wall Street Journal sit down with a16z General Partner Martin Casado on WSJ’s Bold Names to ask whether the AI spending boom is a bubble waiting to burst. Marti...

5 Feb 29min

Why America’s Health Crisis Is an Incentive Problem

Why America’s Health Crisis Is an Incentive Problem

a16z general partner Erik Torenberg speaks with Justin Mares, founder and CEO of Truemed. They discuss why American health outcomes are so poor compared to the rest of the developed world, how crop su...

4 Feb 41min

Populärt inom Business & ekonomi

badfluence
framgangspodden
varvet
rss-jossan-nina
uppgang-och-fall
rss-borsens-finest
rss-svart-marknad
avanzapodden
fill-or-kill
lastbilspodden
bathina-en-podcast
borsmorgon
rss-inga-dumma-fragor-om-pengar
24fragor
rss-dagen-med-di
dynastin
rss-kort-lang-analyspodden-fran-di
tabberaset
loungepodden
rikatillsammans-om-privatekonomi-rikedom-i-livet