Struggling with Central Sleep Apnea? TPNS May Be the Answer
SleepTech Talk1 Dec 2025

Struggling with Central Sleep Apnea? TPNS May Be the Answer

This special episode is brought to you by Zoll Respicardia


In this episode of SleepTech Talk, we explore the newest breakthroughs in treating Central Sleep Apnea (CSA).
Our guest, Timothy Morgenthaler, MD, Professor and Vice Chair, Quality and Affordability at the Mayo Clinic, and past President of the American Academy of Sleep Medicine (AASM), helps explain the updated AASM treatment guidelines and how Transvenous Phrenic Nerve Stimulation (TPNS) is now recognized as an effective therapy for CSA.

We also dive deep into the Remede implant, an FDA-approved TPNS device that stimulates the phrenic nerve to help patients breathe normally during sleep. Dr. Morgenthaler breaks down how it works, which patients may benefit most, and what the AASM’s new recommendations mean for clinicians and patients going forward.

Main topics we cover:

  • What’s new in the AASM guidelines for Central Sleep Apnea (2025 update)
  • Why TPNS is now an accepted therapy for CSA
  • How the Remede implant works and who it helps
  • Differences between obstructive, central, and complex sleep apnea
  • Real-world impact of the updated guidelines on patient care
  • Where TPNS fits among PAP therapy, ASV, oxygen, medications, and other treatments

Whether you’re a sleep clinician, technologist, or someone affected by sleep apnea, this episode provides a clear, practical breakdown of the latest evidence-based options for CSA.

Learn more about Remede at

https://remede.zoll.com/


ABOUT SLEEPTECH TALK
SleepTech Talk brings together leaders in sleep medicine, technology, and innovation to explore the tools and trends shaping the future of sleep health.


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Subscribe to SleepTech Talk for more insights into sleep apnea, CPAP therapy, and innovations shaping the future of sleep care.

Whether you’re a sleep professional or a healthcare innovator, this episode explores the intersection of technology, patient care, and sleep medicine.

Learn more about the show at

https://www.sleeptechtalk.com/thetechroom



Credits:

Audio/ Video: Diego R Mannikarote; Music: Pierce G Mannikarote

Hosts: J. Emerson Kerr, Robert Miller, Gerald George Mannikarote


Copyright: ⓒ 2025 SleepTech Talk Productions

Episode 112


The views and opinions expressed by guests on SleepTech Talk are their own and do not necessarily reflect those of the podcast hosts or SleepTech Talk as a whole. This podcast is intended for educational and informational purposes only and should not be considered medical advice. Listeners are encouraged to consult with a qualified healthcare professional for any medical concerns or questions.


Sleep apnea, obstructive sleep apnea, oral sleep appliance, inspire, surgery, sleep surgery, CPAP, AI, Artificial Intelligence

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