#28: Hidradenitis Suppurativa

#28: Hidradenitis Suppurativa

In this episode of Inflammatory Content, Dr. Kellen Cavagnero explores the debilitating skin disease hidradenitis suppurativa (HS) and takes a deep dive into a recent Immunity paper that comprehensively examines the role of tertiary lymphoid structures in HS pathogenesis. HS has long defied simple classification, with prevailing disease models emphasizing hair follicle dysfunction, aberrant wound healing, or chronic inflammation. This work adds a new dimension by implicating autoimmunity as a central contributor to HS pathogenesis, further underscoring the complexity of the disease.


Relevant Links:

• Paper: https://pmc.ncbi.nlm.nih.gov/articles/PMC12404358/

• Commentary: https://pmc.ncbi.nlm.nih.gov/articles/PMC11790253/


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Stay curious and keep exploring at www.inflammatorycontent.com

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Avsnitt(28)

#27: A Surprising New Role for Neutrophils in Wound Healing

#27: A Surprising New Role for Neutrophils in Wound Healing

In this episode of Inflammatory Content, Dr. Kellen Cavagnero breaks down a new Nature paper showing that a subset of skin neutrophils doesn’t just fight bacteria—they also build extracellular matrix ...

20 Aug 202529min

#26: Spatial Proteomics Uncovers a Lifesaving Treatment for Severe Skin Drug Reactions

#26: Spatial Proteomics Uncovers a Lifesaving Treatment for Severe Skin Drug Reactions

In this episode of Inflammatory Content, Dr. Kellen Cavagnero dives into a landmark 2024 Nature study by Thierry Nordman and colleagues, titled “Spatial proteomics identifies JAKi as treatment for a l...

5 Juli 202518min

#25: Immuno-endocrinology with Dr. Dequina Nicholas, Ph.D.

#25: Immuno-endocrinology with Dr. Dequina Nicholas, Ph.D.

In this episode, Dr. Kellen Cavagnero is joined by Dr. Dequina Nicholas. Dr. Nicholas is an Assistant Professor at the University of California Irvine in the Department of Molecular Biology and Bioche...

8 Mars 20251h 9min

#24: AI Generated Podcast on Immune-Acting Fibroblasts

#24: AI Generated Podcast on Immune-Acting Fibroblasts

Today we’re going to do a journal club, but it will not be your run of the mill journal club. Everyone who knows me knows I am always searching for the latest technology that can increase my efficienc...

16 Jan 202532min

#23: The PhD Fellowship Application Survival Guide

#23: The PhD Fellowship Application Survival Guide

One of the most common questions I get from undergraduate and graduate students is: How do I get a Ph.D. fellowship? During my Ph.D., I was fortunate to be awarded two fellowships, and I’ve received t...

30 Nov 202428min

#22: Mpox (formerly monkeypox) with Dr. Aaron Oom, Ph.D.

#22: Mpox (formerly monkeypox) with Dr. Aaron Oom, Ph.D.

In this episode, Kellen is joined by Dr. Aaron Oom, a Postdoctoral Scholar in the lab of Dr. Mark Mulligan at NYU Langone Health. Aaron is an expert in virology and immunology. He completed his Ph.D. ...

26 Okt 20241h 11min

#21: Functional genomics identifies a novel therapeutic target for inflammatory bowel disease

#21: Functional genomics identifies a novel therapeutic target for inflammatory bowel disease

Genome-wide association studies (GWAS) have identified thousands of disease-associated genetic variants. Many of these variants lie in non-coding regions of the genome, making interpretation of GWAS d...

26 Aug 202433min

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