#113 – Manolis Kellis: Human Genome and Evolutionary Dynamics

Sam Harris is an author, podcaster, and philosopher. Please support this podcast by checking out our sponsors: - Notion: https://notion.com - Indeed: https://indeed.com/lex to get $75 credit - MasterClass: https://masterclass.com/lex to get 15% off EPISODE LINKS: Sam's Website: https://samharris.org Making Sense Podcast: https://www.samharris.org/podcasts/making-sense-episodes Waking Up App: https://www.wakingup.com Sam's YouTube: https://youtube.com/@samharrisorg Sam's Instagram: https://instagram.com/samharrisorg PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/lexfridman - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (09:25) - Empathy and reason (17:17) - Donald Trump (1:00:11) - Military industrial complex (1:04:45) - Twitter (1:28:52) - COVID (2:12:35) - Kanye West (2:29:11) - Platforming (2:47:07) - Joe Rogan (3:03:59) - Bret Weinstein (3:17:38) - Elon Musk (3:29:45) - Artificial Intelligence (3:45:48) - UFOs (3:59:03) - Free will (4:26:17) - Hope for the future

14 Mars 20234h 33min

Chris Voss is a former FBI hostage and crisis negotiator and author of Never Split the Difference: Negotiating As If Your Life Depended On It. Please support this podcast by checking out our sponsors: - Shopify: https://shopify.com/lex to get free trial - Indeed: https://indeed.com/lex to get $75 credit - InsideTracker: https://insidetracker.com/lex to get 20% off EPISODE LINKS: Chris's Instagram: https://instagram.com/thefbinegotiator Chris's Twitter: https://twitter.com/fbinegotiator Chris's Website: https://blackswanltd.com Chris's Masterclass: https://masterclass.com/classes/chris-voss-teaches-the-art-of-negotiation Never Split the Difference (book): https://amzn.to/3J5scNC PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/lexfridman - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (06:31) - Negotiation (12:21) - Reason vs Emotion (27:17) - How to listen (36:06) - Negotiation with terrorists (38:14) - Brittney Griner (39:53) - Putin and Zelenskyy (47:13) - Donald Trump (54:23) - When to walk away (58:37) - Israel and Palestine (1:06:16) - Al-Qaeda (1:11:46) - Three voices of negotiation (1:20:11) - Strategic umbrage (1:23:18) - Mirroring (1:26:29) - Labeling (1:33:55) - Exhaustion (1:36:09) - The word "fair" (1:39:06) - Closing the deal (1:41:03) - Manipulation and lying (1:42:58) - Conversation vs Negotiation (1:54:17) - The 7-38-55 Rule (1:58:16) - Chatbots (2:07:39) - War (2:09:10) - Advice for young people

10 Mars 20232h 15min

Craig Jones, Nicky Rod and Nicky Ryan, together with Ethan Crelinsten are founders of the B-Team, a legendary jiu jitsu team based in Austin, TX. Please support this podcast by checking out our sponsors: - Eight Sleep: https://www.eightsleep.com/lex to get special savings - Athletic Greens: https://athleticgreens.com/lex to get 1 month of fish oil - BetterHelp: https://betterhelp.com/lex to get 10% off EPISODE LINKS: B-Team's Instagram: https://instagram.com/bteamjj/ B-Team's YouTube: https://www.youtube.com/c/bteamjiujitsu B-Team's Website: https://bteamjj.com/ Craig Jones's Instagram: https://instagram.com/craigjonesbjj/ Nicky Rod's Instagram: https://instagram.com/nickyrod247/ Nicky Ryan's Instagram: https://instagram.com/nickyryanbjj/ Craig Jones's Instructionals: https://bjjfanatics.com/collections/craig-jones Nicky Rod's Instructionals: https://bjjfanatics.com/collections/instructional-videos/fighter_nick-rodriguez Nicky Ryan's Instructionals: https://bjjfanatics.com/collections/instructional-videos/fighter_nicky-ryan PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/lexfridman - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (06:21) - B-Team (11:57) - Winning and losing (19:43) - Danaher Death Squad (DDS) (37:13) - Nicky Rod vs Gordon Ryan (53:47) - Steroids (1:08:31) - White belts (1:16:40) - Alexander Volkanovski vs Islam Makhachev (1:36:15) - Greatest MMA fighter of all time (1:38:43) - Dagestani fighters (1:40:00) - Conor McGregor (1:42:39) - Strength training and injuries (1:55:03) - Pre-match ritual (2:01:34) - Toughest match (2:05:25) - Positional training (2:11:59) - Perfect training week (2:14:49) - Overtraining (2:17:08) - Advice for beginners (2:25:17) - Takedowns and submissions (2:30:55) - Ego (2:35:24) - Lion vs bear (2:40:15) - Street fights (2:42:17) - Money and friendship

6 Mars 20232h 54min

Ginni Rometty is a former long-time CEO, president, and chairman of IBM. Please support this podcast by checking out our sponsors: - Athletic Greens: https://athleticgreens.com/lex to get 1 month of fish oil - ExpressVPN: https://expressvpn.com/lexpod to get 3 months free - InsideTracker: https://insidetracker.com/lex to get 20% off EPISODE LINKS: Ginni's book: https://amzn.to/3KFuXHY Ginni's Twitter: https://twitter.com/GinniRometty Ginni's linktr.ee: https://linktr.ee/GinniRometty One Ten Website: https://oneten.org PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/lexfridman - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (05:22) - IBM (15:02) - Hiring (20:19) - Leadership (27:02) - Hard work (32:43) - Adversity (39:41) - Power (53:07) - Sacrifice (58:13) - Taking over as CEO (1:16:27) - Negotiating (1:21:34) - Deep Blue vs Garry Kasparov (1:26:52) - IBM Watson (1:46:45) - Work-life balance (1:53:49) - Advice for young people

2 Mars 20231h 56min

Aaron Smith-Levin is a former Scientologist, Vice President of the Aftermath Foundation, and host of the Growing Up In Scientology YouTube channel. Please support this podcast by checking out our sponsors: - Green Chef: https://greenchef.com/lex60 and use code lex60 to get 60% off plus free shipping - InsideTracker: https://insidetracker.com/lex to get 20% off - Athletic Greens: https://athleticgreens.com/lex to get 1 month of fish oil EPISODE LINKS: Aaron's YouTube: https://youtube.com/@GrowingUpInScientology Aaron's Twitter: https://twitter.com/GrowingupinSCN The Aftermath Foundation: https://theaftermathfoundation.org SP Shop: https://thespshop.com Books mentioned: 1. A Billion Years: https://amzn.to/3EpLiMM 2. Blown for Good: https://amzn.to/3IqaZxN PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/lexfridman - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (06:00) - Thetans (09:59) - Dianetics (22:02) - God (32:38) - Sea Org (36:48) - Auditing (57:01) - Control (1:07:25) - David Miscavige (1:16:32) - Xenu (1:32:26) - Secrecy (1:38:29) - Mike Rinder (1:45:36) - Separation of families (1:52:30) - Tom Cruise (1:56:23) - Sin (2:01:19) - Corruption

25 Feb 20232h 17min

Tim Urban is the author of the blog Wait But Why and a new book What's Our Problem?: A Self-Help Book for Societies. Please support this podcast by checking out our sponsors: - House of Macadamias: https://houseofmacadamias.com/lex and use code LEX to get 20% off your first order - Indeed: https://indeed.com/lex to get $75 credit - Athletic Greens: https://athleticgreens.com/lex to get 1 month of fish oil EPISODE LINKS: Tim's new book: https://waitbutwhy.com/whatsourproblem Tim's Twitter: https://twitter.com/waitbutwhy Tim's Website: https://waitbutwhy.com Tim's Instagram: https://instagram.com/timurban Tim's TED talk: https://www.youtube.com/watch?v=Rk5C149J9C0 PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/lexfridman - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (05:48) - Human history (21:47) - Greatest people in history (29:35) - Social media (36:17) - Good times and bad times (47:48) - Wisdom vs stupidity (49:55) - Utopia (1:04:05) - Conspiracy theories (1:17:16) - Arguing on the Internet (1:37:16) - Political division (1:47:10) - Power games (1:55:09) - Donald Trump and Republican Party (2:12:17) - Social justice (2:34:59) - Censorship gap (2:42:30) - Free speech (2:46:33) - Thinking and universities (2:54:56) - Liv Boeree joins conversation (3:07:15) - Hopes for the future

20 Feb 20233h 10min

Andrew Strominger is a theoretical physicist at Harvard. Please support this podcast by checking out our sponsors: - Eight Sleep: https://www.eightsleep.com/lex to get special savings - Rocket Money: https://rocketmoney.com/lex - Indeed: https://indeed.com/lex to get $75 credit - ExpressVPN: https://expressvpn.com/lexpod to get 3 months free EPISODE LINKS: Andrew's website: https://www.physics.harvard.edu/people/facpages/strominger Andrew's papers: Soft Hair on Black Holes: https://arxiv.org/abs/1601.00921 Photon Rings Around Warped Black Holes: https://arxiv.org/abs/2211.01674 PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/lexfridman - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (06:34) - Black holes (11:37) - Albert Einstein (31:05) - Quantum gravity (35:17) - String theory (46:05) - Holographic principle (54:02) - De Sitter space (59:14) - Speed of light (1:06:02) - Black hole information paradox (1:13:41) - Soft particles (1:22:48) - Physics vs mathematics (1:31:58) - Theory of everything (1:47:20) - Time (1:49:45) - Photon rings (2:05:26) - Thought experiments (2:13:47) - Aliens (2:19:25) - Nuclear weapons

15 Feb 20232h 25min

Aella is a sex researcher, writer, and sex worker. Please support this podcast by checking out our sponsors: - House of Macadamias: https://houseofmacadamias.com/lex and use code LEX to get 20% off your first order - Athletic Greens: https://athleticgreens.com/lex to get 1 month of fish oil - InsideTracker: https://insidetracker.com/lex to get 20% off EPISODE LINKS: Aella's Website: https://knowingless.com/ Aella's Twitter: https://twitter.com/aella_girl/ Aella's OnlyFans: https://onlyfans.com/aella_girl/ Askhole card game: https://askhole.io/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/lexfridman - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (06:14) - Uncertainty (13:51) - Sex, power, and death (26:21) - Free will (27:46) - Consciousness (37:41) - Childhood (50:39) - Dancing (1:03:56) - Casual sex (1:06:10) - Camming (1:21:05) - OnlyFans (1:31:19) - Dating (1:47:11) - Escorting (2:05:12) - Emotion vs reason (2:13:17) - Love (2:20:50) - Polyamory (2:29:44) - Monogamy (2:36:14) - Sex fetishes (2:53:42) - Dominance and submissiveness (3:03:23) - Psychedelics (3:22:35) - Romance (3:30:05) - Body count (3:39:51) - Porn (3:43:10) - Mortality (3:45:46) - AI (3:56:26) - Rationalist discourse (4:00:18) - Meaning of life

10 Feb 20234h 2min