Plain English BEST OF: If GLP-1 Drugs Are Good for Everything, Should We All Be on Them?

Plain English BEST OF: If GLP-1 Drugs Are Good for Everything, Should We All Be on Them?

Throughout December and January, we’re going to be re-airing some of our favorite episodes of the past year and beyond. This list includes interviews that really stuck with me and some others that you guys had tons of feedback and thoughts on … including this one! “If GLP-1 Drugs Are Good for Everything, Should We All Be on Them?” originally aired September 16, 2025.If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek ThompsonGuests: David D’Alessio and Randy SeeleyProducer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

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The Future of GLP-1 Drugs and AI Medicine, With Eli Lilly CEO David Ricks

The Future of GLP-1 Drugs and AI Medicine, With Eli Lilly CEO David Ricks

The GLP-1 drug revolution has taken the medicine world by storm. I’ve done several episodes on the science of GLP-1s. But we’ve never done an episode like this before, where we talk to one of the most...

24 Feb 1h 7min

The Supreme Court Strikes Down Trump’s Tariffs. Now What?

The Supreme Court Strikes Down Trump’s Tariffs. Now What?

Donald Trump suffered a huge blow Friday when the Supreme Court struck down the centerpiece of his economic policy: his vast system of tariffs. So, what happens now? Harvard’s Jason Furman explains th...

21 Feb 41min

The Media Theory That Explains “99% of Everything”

The Media Theory That Explains “99% of Everything”

In the mid-20th century, a group of media and communications scholars proposed that the shift from spoken to written language—from orality to literacy—transformed our politics, our media, our social r...

17 Feb 1h 3min

"America Isn’t Ready for What AI Will Do to Jobs"

"America Isn’t Ready for What AI Will Do to Jobs"

In his epic cover story for The Atlantic this month, staff writer Josh Tyrangiel spoke to dozens of economists, workers, tech CEOs, and AI experts about the danger that artificial intelligence might p...

13 Feb 1h 6min

The Meltdown at The Washington Post—and the Crisis in News

The Meltdown at The Washington Post—and the Crisis in News

Hello! I’m back from paternity leave just in time to talk about the biggest media earthquake of the year (so far): the Washington Post meltdown. For decades, the Post was a journalistic gem with super...

11 Feb 1h 11min

Plain English BEST OF: What’s the Matter With America’s Food?

Plain English BEST OF: What’s the Matter With America’s Food?

Throughout December and January, we’ve been re-airing some of our favorite episodes of the past year and beyond, and today's episode marks the end of our "best of" series for this year! This list incl...

3 Feb 52min

Plain English BEST OF: This Is How the AI Bubble Could Burst

Plain English BEST OF: This Is How the AI Bubble Could Burst

Throughout December and January, we’re going to be re-airing some of our favorite episodes of the past year and beyond. This list includes interviews that really stuck with me and some others that you...

27 Jan 59min

Plain English BEST OF: The Healthiest "Super-Agers" Have One Thing in Common, According to a 25-Year Study

Plain English BEST OF: The Healthiest "Super-Agers" Have One Thing in Common, According to a 25-Year Study

Throughout December and January, we’re going to be re-airing some of our favorite episodes of the past year and beyond. This list includes interviews that really stuck with me and some others that you...

20 Jan 41min

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