#546: Self hosting apps for Python people
The cloud is convenient until it isn't. You upload your photos, sync your contacts, click through the cookie banners. Then prices go up again or you read about a family that lost their entire Google a...
27 Apr 1h 3min
#545: OWASP Top 10 (2025 List) for Python Devs
The OWASP Top 10 just got a fresh update, and there are some big changes: supply chain attacks, exceptional condition handling, and more. Tanya Janca is back on Talk Python to walk us through every si...
16 Apr 1h 6min
#544: Wheel Next + Packaging PEPs
When you pip install a package with compiled code, the wheel you get is built for CPU features from 2009. Want newer optimizations like AVX2? Your installer has no way to ask for them. GPU support? Yo...
10 Apr 1h 11min
#543: Deep Agents: LangChain's SDK for Agents That Plan and Delegate
When you type a question into ChatGPT, the model only has what you typed to work with. But tools like Claude Code can plan, iterate, test, and recover from mistakes. They work more like we do. The dif...
1 Apr 1h 3min
#542: Zensical - a modern static site generator
If you've built documentation in the Python ecosystem, chances are you've used Martin Donath's work. His Material for MKDocs powers docs for FastAPI, uv, AWS, OpenAI, and tens of thousands of other pr...
25 Mars 1h 4min
#541: Monty - Python in Rust for AI
When LLMs write code to accomplish a task, that code has to actually run somewhere. And right now, the options aren't great. Spin up a sandboxed container and you're paying a full second of cold start...
19 Mars 1h 5min
#540: Modern Python monorepo with uv and prek
Monorepos -- you've heard the talks, you've read the blog posts, maybe you've seen a few tantalizing glimpses into how Google or Meta organize their massive codebases. But it's often in the abstract a...
13 Mars 1h 2min
#539: Catching up with the Python Typing Council
You're adding type hints to your Python code, your editor is happy, autocomplete is working great. But then you switch tools and suddenly there are red squiggles everywhere. Who decides what a float a...
6 Mars 1h 1min
