#545: OWASP Top 10 (2025 List) for Python Devs

#545: OWASP Top 10 (2025 List) for Python Devs

The OWASP Top 10 just got a fresh update, and there are some big changes: supply chain attacks, exceptional condition handling, and more. Tanya Janca is back on Talk Python to walk us through every single one of them. And we're not just talking theory, we're going to turn Claude Code loose on a real open source project and see what it finds. Let's do it.

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#557: Security of everything at PyCon 2026

#557: Security of everything at PyCon 2026

Security has always been the vegetables of software. Everyone agrees it matters, and somehow it never quite makes it onto the plate. At PyCon US this year, that changed. For the first time ever, secur...

2 Aug 1h 8min

#556: Updates on Django's Async Story

#556: Updates on Django's Async Story

For years, "Django and async" came with an asterisk. The docs themselves warned you off it. Scary performance notes, a story that felt half-finished. Well, that story just got rewritten, literally, an...

26 Juli 1h 4min

#555: Marimo Pair - A Canvas for Agent + Developers Collaboration

#555: Marimo Pair - A Canvas for Agent + Developers Collaboration

Coding agents have gotten really good at one kind of work. You scope a feature, edit some files, run the tests, ship it. It all happens on disk. But that is not how data work feels. You load something...

13 Juli 1h 4min

#554: Trustworthy AI in Healthcare and Longevity

#554: Trustworthy AI in Healthcare and Longevity

You ask an AI a question and it answers with total confidence. Most of the time, a confidently wrong answer is just an annoyance. But what if the question is medical, and there's a real patient on the...

10 Juli 1h

#553: All of our tools

#553: All of our tools

This episode is a fun crossover from our Python news and tips podcast, Python Bytes. We have had some big changes over there. Brian Okken has moved on and Calvin Hendryx-Parker has joined the show as ...

26 Juni 55min

#552: Astral joins OpenAI

#552: Astral joins OpenAI

OpenAI just acquired Astral, the company behind uv, Ruff, and ty. And if your first thought was "wait, is uv toast?", you are not alone. But here's the twist Charlie Marsh shared with me: he thinks th...

17 Juni 1h 5min

#551: Stroll Down Startup Lane - 2026

#551: Stroll Down Startup Lane - 2026

If you've ever been to PyCon, you know one of the best parts of the expo hall is Startup Row, a stretch of booths where early-stage companies built on Python show off what they're creating. But only a...

11 Juni 1h 48min

#550: AI Contributions and Maintainer Load in Open Source

#550: AI Contributions and Maintainer Load in Open Source

You wake up, brew the coffee, open GitHub, and there it is. Another pull request on your open source project. Thirteen thousand lines added. No issue filed first. No discussion. Just "here, please rev...

30 Maj 1h 2min

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