386: The high stakes for Huntington's patients

386: The high stakes for Huntington's patients

Biotech company UniQure is set to meet with the Food and Drug Administration to discuss the path forward for its gene therapy for Huntington's disease, and the outcome could be potentially devastating for patients. That's what patient advocate Lauren Holder says on the latest episode of “The Readout LOUD,” STAT’s weekly biotech podcast. Holder joins the podcast for an in-depth discussion of how the regulator's changing perspective on UniQure's trial affects patients, and patients' attempts to petition the agency to reverse course. Adam, Elaine, and Allison also chat about the latest news in the life sciences, including the new slate of drug prices negotiated by Medicare, a rise in pharmaceutical industry lobbying, and a halt on another gene therapy trial.

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Avsnitt(417)

Why two promising heart drugs flopped and what's next

Why two promising heart drugs flopped and what's next

On this week’s episode of “The Readout LOUD”: The pharma industry invested billions of dollars to develop drugs heralded as the next era in the treatment of heart disease — but why did they fail? And ...

10 Sep 30min

411: Capricor's data clash and a fugitive in the C-suite

411: Capricor's data clash and a fugitive in the C-suite

Is the Food and Drug Administration taking inconsistent approaches to Duchenne muscular dystrophy drugs? How will a new batch of drug executives shake up their companies? And why is Adam talking to a ...

30 Juli 36min

410: A father’s mission to save his daughter, and allegations on telehealth GLP-1 prescribing

410: A father’s mission to save his daughter, and allegations on telehealth GLP-1 prescribing

What does it take to develop a therapy for an ultra-rare disease? What are the allegations against a telehealth company that’s partnered with Novo Nordisk? And has a wanted fugitive been posing as a b...

23 Juli 1h 4min

409: Predicting biotech clinical trials & a new Alzheimer's drug controversy

409: Predicting biotech clinical trials & a new Alzheimer's drug controversy

On this week’s episode of "The Readout LOUD": The Kalshi prediction markets are coming for biotech, plus the controversy over an experimental Alzheimer’s disease treatment from Biogen. Kalshi, the ma...

16 Juli 35min

408: Whistleblower takes on health insurance and FDA commissioner candidates

408: Whistleblower takes on health insurance and FDA commissioner candidates

Why does getting family health insurance through a job cost as much as buying a new car? How did a whistleblower take on an insurance contractor? And who might be the new Food and Drug Administration ...

9 Juli 43min

407: The mysterious case of Eli Lilly's obesity drug

407: The mysterious case of Eli Lilly's obesity drug

Who got exclusive access to Eli Lilly's highly anticipated obesity candidate? Why are drugmakers spending so much money on acquisitions? And are hair loss drugs a good investment? We discuss all that...

25 Juni 42min

406: New hope in treating Huntington's disease and a report card on RFK Jr.'s promises

406: New hope in treating Huntington's disease and a report card on RFK Jr.'s promises

This week: New hope for people living with Huntington’s disease, and a report card on RFK Jr.’s effort to remake health in America.  The Food and Drug Administration reversed its opposition to a clos...

18 Juni 36min

405: An obesity drug deep-dive, and peptides move mainstream

405: An obesity drug deep-dive, and peptides move mainstream

Can any of the new obesity medications in development stand out from the pack? Which company just broke records with its IPO? And will the Food and Drug Administration allow greater access to experime...

11 Juni 36min

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