From Drug Story: Lipitor and Heart Disease

From Drug Story: Lipitor and Heart Disease

This is an episode of Drug Story, a podcast by Thomas Goetz. You can find the rest of the series at https://www.drugstory.co/podcast Once you turn 40, it seems like half the people you know are taking a statin drug. You know, because their cholesterol is high, and to prevent heart disease down the line. It makes sense: better safe than sorry. This is a huge triumph for preventive medicine. Statin drugs have saved (or improved) the lives of millions of people because they acted early. This is how medicine (and public health) is supposed to work. But the devil is in the details. Like all drugs, statins have side effects. And when they are prescribed for many millions of people, the math means that millions of people will not, in fact, get any benefit from the drug. It turns out that atorvastatin (and other statin drugs) may be the most over-prescribed drugs in the history of medicine. And therein lies a Drug Story. This episode includes perspective from Rita Redberg, MD, cardiologist and former editor in chief at JAMA Internal Medicine.

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Avsnitt(417)

Why two promising heart drugs flopped and what's next

Why two promising heart drugs flopped and what's next

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411: Capricor's data clash and a fugitive in the C-suite

411: Capricor's data clash and a fugitive in the C-suite

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30 Juli 36min

410: A father’s mission to save his daughter, and allegations on telehealth GLP-1 prescribing

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23 Juli 1h 4min

409: Predicting biotech clinical trials & a new Alzheimer's drug controversy

409: Predicting biotech clinical trials & a new Alzheimer's drug controversy

On this week’s episode of "The Readout LOUD": The Kalshi prediction markets are coming for biotech, plus the controversy over an experimental Alzheimer’s disease treatment from Biogen. Kalshi, the ma...

16 Juli 35min

408: Whistleblower takes on health insurance and FDA commissioner candidates

408: Whistleblower takes on health insurance and FDA commissioner candidates

Why does getting family health insurance through a job cost as much as buying a new car? How did a whistleblower take on an insurance contractor? And who might be the new Food and Drug Administration ...

9 Juli 43min

407: The mysterious case of Eli Lilly's obesity drug

407: The mysterious case of Eli Lilly's obesity drug

Who got exclusive access to Eli Lilly's highly anticipated obesity candidate? Why are drugmakers spending so much money on acquisitions? And are hair loss drugs a good investment? We discuss all that...

25 Juni 42min

406: New hope in treating Huntington's disease and a report card on RFK Jr.'s promises

406: New hope in treating Huntington's disease and a report card on RFK Jr.'s promises

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18 Juni 36min

405: An obesity drug deep-dive, and peptides move mainstream

405: An obesity drug deep-dive, and peptides move mainstream

Can any of the new obesity medications in development stand out from the pack? Which company just broke records with its IPO? And will the Food and Drug Administration allow greater access to experime...

11 Juni 36min

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