#62: GLP-1s: Life-Changing Results… at What Cost?

#62: GLP-1s: Life-Changing Results… at What Cost?

A medicine that quiets food noise, trims 15 to 20 percent of body weight, and even lowers the risk of heart events sounds like a fantasy—until you meet GLP-1 drugs. We dig into what makes semaglutide and tirzepatide so different, how they rewire satiety signals, and why their impact extends beyond the scale to blood sugar, blood pressure, and cardiovascular outcomes. Along the way, we get candid about the trade-offs: GI side effects, lean mass loss, and the reality that stopping often means r...

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Avsnitt(75)

Longevity Summarized: The Compass, the Detour, and the Parking Brake

Longevity Summarized: The Compass, the Detour, and the Parking Brake

After 70 episodes, I've noticed a pattern that keeps showing up in every corner of longevity, wellness, and medicine: people don’t fail because they “don’t care.” They fail because the signal is burie...

2 Juni 24min

Diet soda, Twinkies, and the Questions that Matter

Diet soda, Twinkies, and the Questions that Matter

Episode Summary: In this episode, I look at diet soda, artificial sweeteners, and the real-world question that matters most: compared with what, at what dose, for whom, and at what tradeoff? Diet Coke...

21 Maj 28min

What’s Wrong With Me?” What AI Gets Right — And What It Gets Really Wrong

What’s Wrong With Me?” What AI Gets Right — And What It Gets Really Wrong

In this episode, I explore where AI can genuinely help with health questions, where it can fall dangerously short, and how to use it more wisely before trusting it with decisions that really matter. A...

12 Maj 32min

#69 Being Happy:  Physiology Often Beats Insight

#69 Being Happy: Physiology Often Beats Insight

In this episode, I explore a difficult but important idea: when it comes to depression, anxiety, fear, and emotional suffering, changing physiology often works better than understanding the story behi...

30 Apr 21min

When Acupuncture and Massage Work—and When They Don’t

When Acupuncture and Massage Work—and When They Don’t

This episode explores what massage and acupuncture can genuinely help with, where the benefits appear to be mostly short term, and where the evidence simply does not support the bigger claims. Massage...

21 Apr 20min

#67: Why Smart People Fall For Health Headlines

#67: Why Smart People Fall For Health Headlines

“All natural.” “Doctor recommended.” “Used for 5,000 years.” If you’ve ever felt your hand reach for a product before your brain finishes thinking, you’re not alone and you’re not broken. We dig into ...

9 Apr 34min

#67 Stress Reduction: What Actually Works—and What’s Just Wellness Hype

#67 Stress Reduction: What Actually Works—and What’s Just Wellness Hype

Stress is everywhere and so is the marketing. Nearly half of US adults say they feel stressed often, and the wellness world is ready with a supplement, a lab panel, or a pricey device for every sympto...

1 Apr 32min

#66: A big coffee study won't change what I do....

#66: A big coffee study won't change what I do....

Visit my website Bold claims make great headlines; clear evidence makes better habits. We take a hard look at the widely shared study suggesting two to three cups of coffee cut dementia risk by 20 p...

19 Mars 18min

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