HOW OPIOIDS ACTUALLY WORK IN THE BODY (CELLULAR MECHANISM EXPLAINED) │ EP90
Atomic Anesthesia10 Mars

HOW OPIOIDS ACTUALLY WORK IN THE BODY (CELLULAR MECHANISM EXPLAINED) │ EP90

Welcome to the Atomic Anesthesia podcast hosted by CRNA professor Dr. Rhea Temmermand and Co-Founder Sachi Lord. On this show, you'll hear clear, clinically grounded discussions designed for nurse anesthesia residents and CRNAs who want to feel more confident in complex pharmacology, physiology, and real-world anesthesia decision-making.

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In this episode:

  1. How opioids produce analgesia by decreasing synaptic transmission in central pain pathways rather than blocking nerve conduction
  2. μ, κ, and δ opioid receptor pharmacology and how Gi-coupled GPCR signaling alters calcium, potassium, and cAMP
  3. How opioids reduce pain by suppressing ascending nociceptive signaling and enhancing descending inhibitory pathways
  4. The physiologic basis of common opioid effects including respiratory depression, sedation, bradycardia, and GI effects

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Avsnitt(105)

COMPLEX I, SEVOFLURANE, AND THE VENEZUELAN MITOCHONDRIAL VARIANT │ EP105

COMPLEX I, SEVOFLURANE, AND THE VENEZUELAN MITOCHONDRIAL VARIANT │ EP105

A recently identified genetic mutation, passed down on the maternal line, can cause otherwise healthy patients to develop severe and often permanent neurological injury after routine sevoflurane expos...

31 Juli 13min

PROPOFOL: THE DRUG YOU THINK YOU KNOW │ EP104

PROPOFOL: THE DRUG YOU THINK YOU KNOW │ EP104

Propofol, a cornerstone in anesthesia practice, functions as a positive allosteric modulator at the GABA-A receptor. This episode explores its receptor pharmacology, the mechanisms behind its dose-dep...

28 Juli 12min

HIGH & TOTAL SPINAL: THE EARLIEST SYMPTOMS YOU'LL NEED TO KNOW FOR BOARDS │ EP103

HIGH & TOTAL SPINAL: THE EARLIEST SYMPTOMS YOU'LL NEED TO KNOW FOR BOARDS │ EP103

Welcome to the Atomic Anesthesia podcast hosted by CRNA professor Dr. Rhea Temmermand and Co-Founder Sachi Lord. On this show, you'll hear clear, clinically grounded discussions designed for nurse ane...

23 Juli 14min

THE STUDENT-PRECEPTOR RELATIONSHIP: WHAT TO EXPECT, HOW TO THRIVE, AND WHAT ACTUALLY MATTERS (PART 2) │ EP102

THE STUDENT-PRECEPTOR RELATIONSHIP: WHAT TO EXPECT, HOW TO THRIVE, AND WHAT ACTUALLY MATTERS (PART 2) │ EP102

Welcome to the Atomic Anesthesia podcast hosted by CRNA professor Dr. Rhea Temmermand and Co-Founder Sachi Lord. On this show, you'll hear clear, clinically grounded discussions designed for nurse ane...

20 Juli 29min

THE STUDENT-PRECEPTOR RELATIONSHIP: WHAT TO EXPECT, HOW TO THRIVE, AND WHAT ACTUALLY MATTERS (PART 1) │ EP101

THE STUDENT-PRECEPTOR RELATIONSHIP: WHAT TO EXPECT, HOW TO THRIVE, AND WHAT ACTUALLY MATTERS (PART 1) │ EP101

Welcome to the Atomic Anesthesia podcast hosted by CRNA professor Dr. Rhea Temmermand and Co-Founder Sachi Lord. On this show, you'll hear clear, clinically grounded discussions designed for nurse ane...

16 Juli 41min

THE BIGGEST THING HOLDING YOU BACK (PSST...ITS NOT YOUR TALENT) │ EP100

THE BIGGEST THING HOLDING YOU BACK (PSST...ITS NOT YOUR TALENT) │ EP100

Welcome to the Atomic Anesthesia podcast hosted by CRNA professor Dr. Rhea Temmermand and Co-Founder Sachi Lord. On this show, you'll hear clear, clinically grounded discussions designed for nurse ane...

14 Juli 25min

MECHANICAL VENTILATION MODE BASICS EVERY SRNA/NAR SHOULD KNOW │ EP99

MECHANICAL VENTILATION MODE BASICS EVERY SRNA/NAR SHOULD KNOW │ EP99

Welcome to the Atomic Anesthesia podcast hosted by CRNA professor Dr. Rhea Temmermand and Co-Founder Sachi Lord. On this show, you'll hear clear, clinically grounded discussions designed for nurse ane...

7 Juli 26min

YOUR COPD PATIENT IS ON THE TABLE - NOW WHAT? │ EP98

YOUR COPD PATIENT IS ON THE TABLE - NOW WHAT? │ EP98

Welcome to the Atomic Anesthesia podcast hosted by CRNA professor Dr. Rhea Temmermand and Co-Founder Sachi Lord. On this show, you'll hear clear, clinically grounded discussions designed for nurse ane...

16 Juni 21min

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