Ep. 566 “This Isn’t Random” — Why You Keep Waking Up in the Middle of the Night | Menopause, Sleep & Insomnia

Ep. 566 “This Isn’t Random” — Why You Keep Waking Up in the Middle of the Night | Menopause, Sleep & Insomnia

Welcome to this week’s Midlife Minute. Many women have been asking why they wake up at 2, 3, or 4 am every night. So today, I'm breaking down 10 common reasons this happens. I’ve also included some research links in the show notes for those who want to learn more. Stay tuned as I unpack the key factors that disrupt women’s sleep in midlife. IN THIS EPISODE, YOU WILL LEARN: Cortisol spikes and sleep disruptions Why caloric restriction and repeated fasting could stress the body and lead to an overactive sympathetic nervous system The link between declining progesterone and nighttime awakenings How chronic under-eating or over-exercising can disrupt sleep, recovery, and metabolic health Why estradiol fluctuations make it harder to stay asleep Alcohol and late-night sugar fragment sleep Hormonal changes during perimenopause/menopause and increased sleep apnea risk How inflammation, leaky gut, and disrupted neurotransmitter production contribute to early awakenings Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow Cynthia’s Menopause Gut Book is on presale now! Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Research Links Progesterone for treatment of symptomatic menopausal women Sympathetic activity and hypothalamo-pituitary-adrenal axis activity during sleep in post-traumatic stress disorder: a study assessing polysomnography with simultaneous blood sampling Progesterone prevents sleep disturbances and modulates GH, TSH, and melatonin secretion in postmenopausal women [EMPLOYMENT OF THE ELDERLY PEOPLE IN THE EUROPEAN UNION AND UKRAINE: REALITIES, PROBLEMS AND PROSPECTS] Obesity and its implications on oncological urological surgery Metastatic phenotype is regulated by estrogen in thyroid cells Soy protein isolate increases urinary estrogens and the ratio of 2:16alpha-hydroxyestrone in men at high risk of prostate cancer NMR at pressures up to 90 GPa

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Ep. 624 Hormone Replacement Therapy: Timing, Safety, and Treatment | Menopause, Perimenopause, Hormone Replacement Therapy

Ep. 624 Hormone Replacement Therapy: Timing, Safety, and Treatment | Menopause, Perimenopause, Hormone Replacement Therapy

Welcome to this week’s Midlife Minute. This episode is dedicated to the overwhelming number of HRT-related questions I’ve received from my community in 2026. Hormone replacement therapy has generated...

30 Juli 27min

Ep. 623 How Your Nervous System Shapes Hormones and Healing with Dr. Tabatha Barber | Menopause, Perimenopause, Hormones

Ep. 623 How Your Nervous System Shapes Hormones and Healing with Dr. Tabatha Barber | Menopause, Perimenopause, Hormones

Today, I’m delighted to reconnect with Dr. Tabatha Barber, also known as The Gutsy Gynecologist. She is a triple board-certified OB-GYN specializing in perimenopause, menopause, and functional medicin...

29 Juli 1h 27min

BONUS: AMA: Creatine's Impact on Metabolic Health and Wellness with Dr. Darren Candow

BONUS: AMA: Creatine's Impact on Metabolic Health and Wellness with Dr. Darren Candow

Today, I am delighted to reconnect with Dr. Darren Candow. Dr. Candow is a distinguished professor and an internationally renowned researcher on creatine monohydrate, nutrition, and physical activity...

27 Juli 53min

Ep. 622 Brain Fog, Cognitive Reserve, and Dementia Prevention with Dr. Tommy Wood | Menopause, Perimenopause, Brain Health

Ep. 622 Brain Fog, Cognitive Reserve, and Dementia Prevention with Dr. Tommy Wood | Menopause, Perimenopause, Brain Health

Today, I’m honored to reconnect with Dr. Tommy Wood. He is a neuroscientist, a performance coach, and an elite-level professional nerd. He's also currently an associate professor of pediatrics and neu...

25 Juli 1h

Ep. 621 Cortisol, Belly Fat, and the Fasting Mistake Most Women Make with Ben Azadi, FDN-P | Menopause, Perimenopause, Keto

Ep. 621 Cortisol, Belly Fat, and the Fasting Mistake Most Women Make with Ben Azadi, FDN-P | Menopause, Perimenopause, Keto

I’m delighted to reconnect with my dear friend Ben Azadi today, in honor of his newly revised book, Keto Flex. Ben is a leading authority on metabolic health, an international Keystone speaker, and t...

22 Juli 52min

BONUS: A Fresh Perspective on Aging: Dr. Youn's Expert Insights

BONUS: A Fresh Perspective on Aging: Dr. Youn's Expert Insights

I am thrilled to connect with my friend and colleague, Dr. Anthony Youn today. Dr. Youn is a nationally recognized board-certified plastic surgeon and the author of many best-selling books. He has a...

20 Juli 1h 12min

Ep. 620 Menopause, Hormones, and the Body’s Terrain with Dr. Sharon Stills | Menopause, Perimenopause, Lymphatic Health

Ep. 620 Menopause, Hormones, and the Body’s Terrain with Dr. Sharon Stills | Menopause, Perimenopause, Lymphatic Health

I am honored to connect with Dr. Sharon Stills today. She is a graduate of naturopathic medical school with extensive training in European biological medicine, bioidentical hormone replacement, and an...

18 Juli 1h 3min

Ep. 619 The Elimination Diet Myth! – Why Blanket Restriction Backfires in Perimenopause | Menopause, Perimenopause & Diet

Ep. 619 The Elimination Diet Myth! – Why Blanket Restriction Backfires in Perimenopause | Menopause, Perimenopause & Diet

Welcome to the latest Midlife Minute episode. Today, we’re talking about elimination diets, iron, and ferritin. I share my personal experience with prolonged antibiotic and antifungal use, clarify wh...

16 Juli 28min

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