Gene Editing and Cholesterol: The Road Less Traveled

Gene Editing and Cholesterol: The Road Less Traveled

In this week's episode we explore gene therapies. We look at what genes are, why mutations can be dangerous, and what methods are being investigated to solve these problems. Then we focus on familial hypercholesterolemia as an example and look at what's being researched today to solve this problem. References: Hoekstra M, Van Eck M. Gene editing for the treatment of hypercholesterolemia. Current Atherosclerosis Reports. 2024 May;26(5):139-46. https://doi.org/verve10.1007/s11883-024-01198-3S...

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Avsnitt(138)

The Secret Box That Changed How Medicines Are Manufactured

The Secret Box That Changed How Medicines Are Manufactured

On this week's episode, we explore the history of one of the most ubiquitous manufacturing tools for producing medicine in living cells: Chinese hamster ovary (CHO) cells. We look at the history, prog...

12 Okt 5min

Why Is Agitation a Symptom of Alzheimer's Disease?

Why Is Agitation a Symptom of Alzheimer's Disease?

In this week's episode we explore the links between anxiety, Alzheimer's, and agitation. We look at how anxiety works, how agitation works, and how Alzheimer's may increase these two. We also jump int...

5 Okt 6min

Counterfeit Peptides, Cartels, and Crypto

Counterfeit Peptides, Cartels, and Crypto

In this week's episode, we look into the world of "grey market" peptides. We explore what peptides are, what the grey market is, and if these unsanctioned "medications" are safe for human use. Share w...

28 Sep 6min

Weight Loss Isn't the Only Thing That Matters for Heart Health

Weight Loss Isn't the Only Thing That Matters for Heart Health

In this week's episode, we review a recently released, randomized research paper that compared three different diets. The study looked at the Mediterranean diet, a low-fat plant-forward diet, and very...

22 Sep 7min

Clearing the Air Around Brain Fog

Clearing the Air Around Brain Fog

In this week's episode, we take a peek into the murky, hazy world of brain fog. This condition/syndrome/symptom is vague and nonspecific, and occurs alongside a wide variety of otherwise unrelated med...

14 Sep 6min

The Unexpected Benefits of Being Observed

The Unexpected Benefits of Being Observed

In this week's episode, written by guest writer Daniel Benton, we explore the Hawthorne Effect. This the phenomenon that people tend to do better in research studies just by being observed. We look in...

7 Sep 4min

When Your Bladder Can’t Take the Pressure

When Your Bladder Can’t Take the Pressure

In this week's episode, we look at the prevalence, pathophysiology, and progress towards a solution to urinary incontinence. We review what urinary incontinence is, look at the different types of inco...

31 Aug 7min

Is Low Testosterone Baked Into Aging?

Is Low Testosterone Baked Into Aging?

In this week's episode, we explore the world of hypogonadism, which typically manifests as low testosterone. We look at what testosterone is, the role it plays in the body, and what happens when testo...

24 Aug 5min

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