Ep 205 Cancer Part 4: Where do things stand today?

Ep 205 Cancer Part 4: Where do things stand today?

For the entirety of our species’ history, our approach to cancer has largely been to react, to design new therapies and better combinations of treatments. This energy has certainly been well-spent, but what if we didn’t have to use treatment at all? Or what if we could minimize the use of aggressive therapies? Prevention and screening represent two under-appreciated pillars of cancer care, and we’re using this final installment in our cancer miniseries to show some appreciation. To grasp the impact that screening and prevention can have, we also need to consider the global landscape of cancer prevalence and incidence - where is it decreasing? Where is it on the rise? Where can intervention or prevention make an impact? As we’ve shown over these four episodes, science and medicine has accumulated a wealth of information about cancer - but the striking racial and socioeconomic disparities in cancer incidence and mortality in the US and around the world demonstrates that that knowledge has not been applied equally. Any proposal to reduce the global cancer burden must address the systemic issues driving these disparities. Tune in for a thought-provoking reflection on the status of cancer today.

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Ep 186 Hypothermia Part 1: How it hurts

Ep 186 Hypothermia Part 1: How it hurts

For all our wondrous adaptations as a species - our big brains, our capacity for language, our opposable thumbs - we humans are not well-equipped to deal with the cold. Take us out of our insulated dw...

2 Sep 202557min

Special Episode: Lina Zeldovich & The Living Medicine

Special Episode: Lina Zeldovich & The Living Medicine

The development of antibiotics was one of the greatest turning points in the history of medicine. Bacterial infections that were once death sentences were cured within a matter of days after administr...

26 Aug 202551min

Ep 185 The Great Smog of London: “Thick, drab, yellow, disgusting”

Ep 185 The Great Smog of London: “Thick, drab, yellow, disgusting”

Some things just go together: peanut butter and jelly, bacon and eggs, milk and cereal, London and smog. Or at least, that’s the way things used to be until the Great Smog of 1952. (Don’t worry, the f...

19 Aug 20251h 14min

Ep 184 The Gallbladder: Humor us

Ep 184 The Gallbladder: Humor us

For most of us, there probably hasn’t been a good reason for you to think about your gallbladder. Ever. Much of the time, it sits there, silently storing, concentrating, and, when needed, churning out...

12 Aug 20251h 22min

Special Episode: Carl Zimmer & Airborne

Special Episode: Carl Zimmer & Airborne

In the first years of the COVID pandemic, a debate raged: was the virus transmitted via respiratory droplets, or was it airborne? For some, this distinction seemed overly technical, pedantic even. But...

5 Aug 202549min

Ep 183 SSRIs Part 2: Action

Ep 183 SSRIs Part 2: Action

Last week, we took you on a journey of discovery and innovation, and this week we’re gonna tell you how the heck it all works. That means a deep dive into the nitty gritty of SSRIs, from what serotoni...

29 Juli 20251h 10min

Ep 182 SSRIs Part 1: Origin

Ep 182 SSRIs Part 1: Origin

Since first hitting the shelves nearly 40 years ago, SSRIs have become one of the most commonly prescribed classes of antidepressants around the world, as well as one of the most discussed and misunde...

22 Juli 20251h 2min

Special Episode: Wendy Chin-Tanner & King of the Armadillos

Special Episode: Wendy Chin-Tanner & King of the Armadillos

We’ve got a very special episode of the TPWKY book club this week! We’re featuring our very first fiction book: King of the Armadillos by Wendy Chin-Tanner. This novel tells the story of a young man n...

15 Juli 202556min

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