TWiP 100: Driving past a milestone

TWiP 100: Driving past a milestone

Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin

The TWiP trifecta solves the case of the Woman from Bolivia with Belly Pain, and discuss a method for population modification of malaria mosquitoes using a Cas9-mediated driver gene.

Links for this episode: Case study for TWiP 100

This week's case is a 27 yo female, native NY, referred to outpatient at CU after seeing OBGYN, told had seen worms in stool and underwear. Inch or two in length, pale white, round, moving, 2-3 weeks of constant abdominal bloating. Sexually active. No particular diet. Travel: works for NGO, refugee camp in Ethiopian-Sudan border, southern Sudan. Last visit month ago. Noticed worms when she got back from last trip. Eats what local people eat. Raw food popular there: kitfo, raw steak tartare, with melted butter. Made from local beef. Did not take malaria prophylaxis, did not avoid local water, does wear sandals. College graduate. Nothing remarkable in family. CBC, liver, metabolic: all normal. Stool not normal: loose, no mucus or blood.

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Avsnitt(285)

TWiP 285: Why Is Cyclospora So Hard to Contain? Parasitologists Explain the 2026 US Outbreak

TWiP 285: Why Is Cyclospora So Hard to Contain? Parasitologists Explain the 2026 US Outbreak

TWiP reviews our current understanding of the biology of Cyclospora, the parasite currently causing a large multistate outbreak in the US traced to contaminated lettuce, and why it is so difficult to ...

6 Aug 52min

TWiP 284: It's not the pork

TWiP 284: It's not the pork

TWiP solves the case of the 39-year-old man originally from Guatemala, who moved to one of the NYC boroughs in 2023 and presented with headaches for nearly 1 year. Hosts: Vincent Racaniello, Daniel Gr...

27 Juli 50min

TWiP 283: Warming up to cryptosporidiosis

TWiP 283: Warming up to cryptosporidiosis

TWiP reviews the projected impact of climate change on the burden of Cryptosporidium in Mali, Kenya, and The Gambia. Hosts: Vincent Racaniello and Christina Naula Subscribe (free): Apple Podcasts, Goo...

7 Juli 1h

TWiP 282: Does he live in New York?

TWiP 282: Does he live in New York?

TWiP solves the case of the nonbinary patient in his 30s with a history HIV/AIDS presenting with 3 weeks of subjective fevers, chills, generalized weakness and voluminous ostomy output. Hosts: Vincent...

24 Juni 53min

TWiP 281: Ants under the influence

TWiP 281: Ants under the influence

TWiP reviews gene expression in wood ants infected with the larval lancet fluke, which causes them to leave their nest and attach to a flower until they are eaten by a grazing mammal. Hosts: Vincent R...

22 Juni 58min

TWiP 280: The wriggling diagnosis

TWiP 280: The wriggling diagnosis

TWiP solves the case of the 3 yo child, who recently immigrated to the US from Central America, in the ER with acute right lower quadrant abdominal pain and a rather active serpiginous wormlike 'thing...

29 Maj 57min

TWiP 279: Tolling for hookworms

TWiP 279: Tolling for hookworms

TWiP reviews a phase 2 clinical trial of a recombinant vaccine against N. americanus glutathione S-transferase-1, an enzyme that performs a crucial enzymatic step in hookworm blood feeding. Hosts: Vin...

1 Maj 50min

TWiP 278: Trichinella from eating bear eyeballs

TWiP 278: Trichinella from eating bear eyeballs

TWiP solves the case of the male in his 20s from Hokkaido, Japan, who developed fatigue and rash, followed by fever and myalgia 6 days later, after eating a raw bear eyeball. Hosts: Vincent Racaniello...

24 Apr 56min

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