Feedback scales the spatial tuning of cortical responses during both visual working memory and long-term memory
The Journal Club28 Apr 2025

Feedback scales the spatial tuning of cortical responses during both visual working memory and long-term memory

We demonstrate that remembering a visual stimulus evokes responses in visual cortex that differ in spatial extent compared to seeing the same stimulus. Perception evokes tuned responses in early visual areas that increase in size up the visual hierarchy. Prior work showed that feedback inputs associated with long-term memory originate from later visual areas with larger receptive fields resulting in uniformly wide spatial tuning even in primary visual cortex. We replicate these results and show that the same pattern holds when maintaining in working memory a recently viewed stimulus. That trial-to-trial difficulty is reflected in the accuracy and precision of these representations suggests that visual cortex is flexibly used for processing visuospatial information, regardless of where that information originates.


Woodry R, Curtis CE, Winawer J. Feedback scales the spatial tuning of cortical responses during both visual working memory and long-term memory. bioRxiv [Preprint]. 2024 Dec 2




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