MSK History Taking: Osteoarthritis vs Rheumatoid Arthritis | OSCE Talk
OSCE Talk27 Nov 2025

MSK History Taking: Osteoarthritis vs Rheumatoid Arthritis | OSCE Talk

In this episode of OSCE Talk we focus on the history and clinical presentation of both rheumatoid and osteoarthritis, alongside its impact on patients.


Key aspects to highlight in this episode include:


  • Joint pain in osteoarthritis worsens with activity, while in rheumatoid arthritis, it can occur at rest.
  • Morning stiffness in rheumatoid arthritis lasts longer than in osteoarthritis.
  • Physical activity with weight loss can help manage osteoarthritis symptoms.
  • Diagnosis of osteoarthritis is often clinical, alongside using XRay to visualise the joint space.
  • LOSS mnemonic- loss of joint space, osteophytes, subchondral cysts, subchondral sclerosis.
  • Rheumatoid arthritis requires aggressive treatment to prevent joint damage, often requiring methotrexate, steroids and other DMARDs
  • Associated factors in RA include uveitis, urinary tract symptoms, gastrointestinal symptoms.
  • Family history plays a significant role in both conditions.
  • Management of osteoarthritis focuses on maintaining function and pain relief.


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