234 | Tobias Warnecke on Cellular Structure and Evolution

234 | Tobias Warnecke on Cellular Structure and Evolution

Eukaryotic cells manage to pull off a number of remarkable feats. One is packing quite a long DNA molecule, with potentially billions of base pairs, into a tiny central nucleus. A key role is played by histones, proteins that provide scaffolding for DNA to wrap around. Histones also appear in archaea (one of the other domains of life), but until recently there wasn't evidence for them in bacteria (the final of the three domains). Todays guest, Tobias Warnecke, is an author on a recent paper that claims to provide such evidence. We discuss this new result, as well as background questions of how cells evolved and what their current structure can teach us about their histories.

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Tobias Warnecke received his Ph.D. in biology from the University of Bath. He is currently a Programme Leader and MRC Investigator at the London Institute of Medical Sciences. He is a co-author on A. Hochner et al. (2023), "Histone-Organized Chromatin in Bacteria."


Avsnitt(418)

293 | Doyne Farmer on Chaos, Crashes, and Economic Complexity

293 | Doyne Farmer on Chaos, Crashes, and Economic Complexity

A large economy is one of the best examples we have of complex dynamics. There are multiple components arranged in complicated overlapping hierarchies, out-of-equilibrium dynamics, nonlinear coupling ...

21 Okt 20241h 11min

292 | Jonathan Birch on Animal Sentience

292 | Jonathan Birch on Animal Sentience

It's not immoral to kick a rock; it is immoral to kick a baby. At what point do we start saying that it is wrong to cause pain to something? This question has less to do with "consciousness" and more ...

14 Okt 20241h 10min

AMA | October 2024

AMA | October 2024

Welcome to the October 2024 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Pat...

7 Okt 20244h 29min

291 | Venki Ramakrishnan on the Biology of Death and Aging

291 | Venki Ramakrishnan on the Biology of Death and Aging

Aging and death happen to the best of us, but there are increasing efforts to do something about it. That effort requires that we have some reasonable understanding of why aging happens, and what proc...

30 Sep 20241h 20min

290 | Hahrie Han on Making Multicultural Democracy Work

290 | Hahrie Han on Making Multicultural Democracy Work

It's a wonder democracy works at all -- a collection of people with potentially different interests have to agree to abide by majority vote even when it goes against their desires. But as we know, it ...

23 Sep 20241h 15min

289 | Cari Cesarotti on the Next Generation of Particle Experiments

289 | Cari Cesarotti on the Next Generation of Particle Experiments

As an experimental facility, the Large Hadron Collider at CERN in Geneva has been extraordinarily successful, discovering the Higgs boson and measuring multiple features of particle-physics interactio...

16 Sep 20241h 21min

288 | Max Richter on the Meaning of Classical Music Today

288 | Max Richter on the Meaning of Classical Music Today

It wasn't that long ago, historically speaking, that you might put on your tuxedo or floor-length evening gown to go out and hear a live opera or symphony. But today's world is faster, more technologi...

9 Sep 20241h 6min

AMA | September 2024

AMA | September 2024

Welcome to the September 2024 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by P...

2 Sep 20243h 50min

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