234 | Tobias Warnecke on Cellular Structure and Evolution

234 | Tobias Warnecke on Cellular Structure and Evolution

Eukaryotic cells manage to pull off a number of remarkable feats. One is packing quite a long DNA molecule, with potentially billions of base pairs, into a tiny central nucleus. A key role is played by histones, proteins that provide scaffolding for DNA to wrap around. Histones also appear in archaea (one of the other domains of life), but until recently there wasn't evidence for them in bacteria (the final of the three domains). Todays guest, Tobias Warnecke, is an author on a recent paper that claims to provide such evidence. We discuss this new result, as well as background questions of how cells evolved and what their current structure can teach us about their histories.

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Tobias Warnecke received his Ph.D. in biology from the University of Bath. He is currently a Programme Leader and MRC Investigator at the London Institute of Medical Sciences. He is a co-author on A. Hochner et al. (2023), "Histone-Organized Chromatin in Bacteria."


Avsnitt(418)

64 | Ramez Naam on Renewable Energy and an Optimistic Future

64 | Ramez Naam on Renewable Energy and an Optimistic Future

The Earth is heating up, and it's our fault. But human beings are not always complete idiots (occasional contrary evidence notwithstanding), and sometimes we can even be downright clever. Dare we imag...

16 Sep 20191h 16min

63 | Solo -- Finding Gravity Within Quantum Mechanics

63 | Solo -- Finding Gravity Within Quantum Mechanics

I suspect most loyal Mindscape listeners have been exposed to the fact that I've written a new book, Something Deeply Hidden: Quantum Worlds and the Emergence of Spacetime. As I release this episode o...

9 Sep 20191h 50min

62 | Michele Gelfand on Tight and Loose Societies and People

62 | Michele Gelfand on Tight and Loose Societies and People

Physicists study systems that are sufficiently simple that it's possible to find deep unifying principles applicable to all situations. In psychology or sociology that's a lot harder. But as I say at ...

2 Sep 20191h 12min

61 | Quassim Cassam on Intellectual Vices and What to Do About Them

61 | Quassim Cassam on Intellectual Vices and What to Do About Them

All of us have been wrong about things from time to time. But sometimes it was a simple, forgivable mistake, while other times we really should have been correct. Properties that systematically preven...

26 Aug 20191h 10min

60 | Lynne Kelly on Memory Palaces, Ancient and Modern

60 | Lynne Kelly on Memory Palaces, Ancient and Modern

Memory takes different forms. Memories can be encoded in the strength of neural connections in our brains, but there's a sense in which photographs and written records are memories as well. What did p...

19 Aug 20191h 15min

59 | Adam Becker on the Curious History of Quantum Mechanics

59 | Adam Becker on the Curious History of Quantum Mechanics

There are many mysteries surrounding quantum mechanics. To me, the biggest mysteries are why physicists haven't yet agreed on a complete understanding of the theory, and even more why they mostly seem...

12 Aug 20191h 40min

58 | Seth MacFarlane on Using Science Fiction to Explore Humanity

58 | Seth MacFarlane on Using Science Fiction to Explore Humanity

Fiction shines a light on the human condition by putting people into imaginary situations and envisioning what might happen. Science fiction expands this technique by considering situations in the fut...

5 Aug 20191h 12min

57 | Astra Taylor on the Promise and Challenge of Democracy

57 | Astra Taylor on the Promise and Challenge of Democracy

"Democracy may not exist, but we'll miss it when it's gone" — or so suggests the title of Astra Taylor's new book. We all know how democracy falls short, in practice, of its lofty ideals; but we can a...

29 Juli 20191h 23min

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