234 | Tobias Warnecke on Cellular Structure and Evolution

234 | Tobias Warnecke on Cellular Structure and Evolution

Eukaryotic cells manage to pull off a number of remarkable feats. One is packing quite a long DNA molecule, with potentially billions of base pairs, into a tiny central nucleus. A key role is played by histones, proteins that provide scaffolding for DNA to wrap around. Histones also appear in archaea (one of the other domains of life), but until recently there wasn't evidence for them in bacteria (the final of the three domains). Todays guest, Tobias Warnecke, is an author on a recent paper that claims to provide such evidence. We discuss this new result, as well as background questions of how cells evolved and what their current structure can teach us about their histories.

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Tobias Warnecke received his Ph.D. in biology from the University of Bath. He is currently a Programme Leader and MRC Investigator at the London Institute of Medical Sciences. He is a co-author on A. Hochner et al. (2023), "Histone-Organized Chromatin in Bacteria."


Avsnitt(419)

33 | James Ladyman on Reality, Metaphysics, and Complexity

33 | James Ladyman on Reality, Metaphysics, and Complexity

Reality is a tricky thing. Is love real? What about the number 5? This is clearly a job for a philosopher, and James Ladyman is one of the world's acknowledged experts. He and his collaborators have b...

11 Feb 20191h 7min

32 | Naomi Oreskes on Climate Change and the Distortion of Scientific Facts

32 | Naomi Oreskes on Climate Change and the Distortion of Scientific Facts

Our climate is in the midst of dramatic changes, driven largely by human activity, with potentially enormous consequences for humanity and other species. That's why science tells us, anyway. But there...

4 Feb 20191h 10min

31 | Brian Greene on the Multiverse, Inflation, and the String Theory Landscape

31 | Brian Greene on the Multiverse, Inflation, and the String Theory Landscape

String theory was originally proposed as a relatively modest attempt to explain some features of strongly-interacting particles, but before too long developed into an ambitious attempt to unite all th...

28 Jan 20191h 11min

30 | Derek Leben on Ethics for Robots and Artificial Intelligences

30 | Derek Leben on Ethics for Robots and Artificial Intelligences

It's hardly news that computers are exerting ever more influence over our lives. And we're beginning to see the first glimmers of some kind of artificial intelligence: computer programs have become mu...

21 Jan 20191h 28min

29 | Raychelle Burks on the Chemistry of Murder

29 | Raychelle Burks on the Chemistry of Murder

Sometimes science is asking esoteric questions about the fundamental nature of reality. Other times, it just wants to solve a murder. Today's guest, Raychelle Burks, is an analytical chemist at St. Ed...

14 Jan 20191h 15min

28 | Roger Penrose on Spacetime, Consciousness, and the Universe

28 | Roger Penrose on Spacetime, Consciousness, and the Universe

Sir Roger Penrose has had a remarkable life. He has contributed an enormous amount to our understanding of general relativity, perhaps more than anyone since Einstein himself -- Penrose diagrams, sing...

7 Jan 20191h 35min

Holiday Message 2018

Holiday Message 2018

There won't be any regular episodes of Mindscape this week or next, as we take a holiday break. Regular service will resume on Monday January 7, 2019. In the meantime, here is a special Holiday Messag...

24 Dec 201844min

27 | Janna Levin on Black Holes, Chaos, and the Narrative of Science

27 | Janna Levin on Black Holes, Chaos, and the Narrative of Science

It's a big universe out there, full of an astonishing variety of questions and puzzles. Today's guest, Janna Levin, is a physicist who has delved into some of the trippiest aspects of cosmology and gr...

17 Dec 20181h 8min

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