TWiV 1330: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Daniel Griffin and Vincent Racaniello opine on the recent executive order on the routine childhood vaccination schedule, the Ebola outbreak in the Congo and Uganda including the fast track trials for 2 vaccine candidates and antivirals, recent Hantavirus infections, use of quarantined "Hantavirus" patients for the governmental propaganda machine, use of ribavirin and other antivirals for Hantavirus associated cardiopulmonary disease, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the measles outbreak in Bangladesh, as well as in a daycare center in Texas in 2025, how to access and pay for Paxlovid, FDA approval of a second COVID-19 antiviral drug, where to go for answers about long COVID-19, use of convalescent sera for COVID-19 treatment and contacting your federal government representative to stop the assault on science and biomedical research.

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Links for this episode

• Childhood Vaccine Hesitancy (NEJM)
• One Year In: Public Views of a Changing Public Health Landscape (Harvard School of Public Health)
• Rotavirus Vaccine Coverage and Potential Barriers Among US Children Born From 2007 to 2024 (Pediatrics)
• Texas reports New World screwworm in 3-week-old calf (CIDRAP)
• USDA Confirms First Case of New World Screwworm in a Dog in Lea County, New Mexico, Fourth Case in Texas (USDA: Animal and Plant Health Inspection Service)
• Confirmed Detections of New World Screwworm (USDA: Animal and Plant Health Inspection Service)
• Mexico reports more human New World screwworm infections (CIDRAP)
• Frequency and persistence of post-acute symptoms after chikungunya, dengue, Zika and malaria in travellers: a prospective multi-centre study (Journal of Travel Medicine)
• Ebola dashboard (ebola.fyi)
• EBOLA:The Democratic Republic of the Congo, 2026 (WHO)
• Bundibugyo virus disease outbreak Democratic Republic of the Congo (WHO: Democratic Republic of Congo)
• Ebola Outbreak: Current Situation (CDC:Ebola)
• Modeled Scenario Projections for the Ebola Disease Outbreak Caused by Bundibugyo Virus, 2026 (CDC: MMWR)
• Assessment of Riskto the U.S. Population from the Ebola Disease Outbreak Caused by Bundibugyo Virus, 2026 (CDC: MMWR)
• How Ebola Disease Spreads (CDC: Ebola)
• Signs and Symptoms of Ebola Disease (CDC: Ebola)
• Hantavirusdashboard (Hantavirus.up)
• Hantavirus on board with Prof. VincentRacaniello (MicrobeTV)
• Some hantavirus-exposed cruise ship passengers return home to finish quarantine (CNN)
• Use of tocilizumab for severe hantavirus pulmonary syndrome: a MEURI case series with contextual comparisons (LANCET: Infectious Diseases)
• First reported case of Andes hantavirus cardiopulmonary syndrome treated with a combination of favipiravir, ribavirin, icatibant and baricitinib (Clinical Microbiology and Infection)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health)
• Utah measles outbreak response (Utah Department of Health and Human Services)
• Utah Measles Dashboard (Utah Department of Health and Human Services)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Anguished Parents, Crying Doctors: Life Amid Utah's Measles Outbreak (Wired)
• Characteristics of Patients Hospitalized with Measles During an Outbreak — West Texas, January–March 2025 (CDC:MMWR)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)
• WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP)
• FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP)
• Weekly surveillance report: cliff notes (CDC FluView)
• OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Respiratory Diseases (Yale School of Public Health)
• Real-world emergence of nirsevimab resistance in breakthrough infections with respiratory syncytial virus-B: a multicentre observational study in France (LANCET: Microbe)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national andregional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Shionogi Announces FDA Approval of XOCOVA® (ensitrelvir), the First and Only Oral Option to Help Prevent COVID-19 Following Exposure (Businesswire)
• SARS-CoV-2 viral shedding and vaccination‑modified effects of oral antivirals in older COVID-19 patients: a retrospective cohort study in Hong Kong (International Journal of Infectious Diseases)
• SARS-CoV-2 vaccination and attenuation of breakthrough infection severity: A systematic global review and meta-analysis (CID)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Metformin on the Presence of COVID-19 Symptoms 6 Months after Infection: The ACTIV-6 Randomized Clinical Trial (CID) Reaching out to US house representative
• Letters read on TWiV 1330
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.