Exploring the Limitations and Potentials of RCTs: Beyond the Gold Standard

Exploring the Limitations and Potentials of RCTs: Beyond the Gold Standard

Are Randomised Controlled Trials (RCTs) always the definitive 'gold standard' in research? In the latest episode of In Silico Trials, Real Impacts!, we explore the nuanced landscape of RCTs, questioning their universal applicability and examining the complexities they often obscure. While RCTs are celebrated for their rigour, this discussion delves into their limitations, particularly when findings are applied across diverse contexts.

Drawing on seminal work by Deaton and Cartwright (2018), this episode highlights the critical role that RCTs play in the medical and social sciences, while underscoring the importance of complementing them with observational studies and theoretical frameworks. Ethical considerations and the need for a more integrated approach to research take centre stage, offering a fresh perspective on evidence generation.

Whether you're a researcher, healthcare professional, or simply curious about scientific methodologies, this episode provides thought-provoking insights into the evolving landscape of research.

Source: Deaton A, Cartwright N. Understanding and misunderstanding randomized controlled trials. Soc Sci Med. 2018 Aug;210:2-21.

Det här avsnittet är hämtat från ett öppet RSS-flöde och publiceras inte av Podme. Det kan innehålla reklam.

Avsnitt(43)

Digital Twins & Virtual Patients: Revolutionising Paediatric Clinical Trials

Digital Twins & Virtual Patients: Revolutionising Paediatric Clinical Trials

Join us for an eye-opening exploration of how virtual patient data is revolutionising paediatric clinical trials. In our upcoming episode, we delve into groundbreaking research that addresses one of h...

30 Juni 202528min

Beyond the Scalpel: How Computer Models Are Rewriting Paediatric Heart Surgery

Beyond the Scalpel: How Computer Models Are Rewriting Paediatric Heart Surgery

This episode explores groundbreaking research from Boston Children's Hospital and Harvard Medical School that demonstrates how multiphysiologic state computational fluid dynamics (CFD) modelling is tr...

23 Juni 202522min

Future-Proofing the UK Life Sciences Sector

Future-Proofing the UK Life Sciences Sector

Are you prepared for the seismic shift transforming UK life sciences careers? This latest "In Silico Trials, Real Impacts!" episode reveals how AI and in silico technologies are creating unprecedented...

16 Juni 202517min

Simpler or Complex: Rethinking Occam's Razor in Modelling Science

Simpler or Complex: Rethinking Occam's Razor in Modelling Science

Is simplicity always the smartest choice in science? Or could complexity be the key to groundbreaking discoveries? This episode explores the evolving role of simplicity and complexity in scientific mo...

2 Juni 202527min

Evaluating Continuous Glucose Monitoring Sensors with in Silico Trials: A Real-World Exemplar

Evaluating Continuous Glucose Monitoring Sensors with in Silico Trials: A Real-World Exemplar

Could computer simulations redefine diabetes care? In this episode, we focus on a real medical product and the role of in silico trials in the transition from the Medtronic Guardian Sensor 3 to the Gu...

25 Maj 202515min

Unveiling Evidence-Based Medicine Plus and Mechanistic Reasoning

Unveiling Evidence-Based Medicine Plus and Mechanistic Reasoning

What is Evidence-Based Medicine Plus? This podcast episode explores the transformative power of computational modelling and simulated clinical trials in medical innovation. Discover the significance o...

19 Maj 202516min

What Underpins Model Credibility? Three Philosophical Perspectives

What Underpins Model Credibility? Three Philosophical Perspectives

How do philosophers of science think about model evaluation? Dive deep into the crucial process of model evaluation, a fundamental step in digital science that determines the effectiveness and precisi...

12 Maj 202519min

Populärt inom Vetenskap

p3-dystopia
dumma-manniskor
allt-du-velat-veta
kapitalet-en-podd-om-ekonomi
doden-hjarnan-kemisten
medicinvetarna
rss-kriminologerna
rss-vetenskapsradion-2
rss-ufobortom-rimligt-tvivel
svd-nyhetsartiklar
rss-vetenskapsradion
sexet
rss-spraket
bildningspodden
rss-ronden
dumforklarat
rss-odla
vetenskapsradion
rss-broccolipodden-en-podcast-som-inte-handlar-om-broccoli
rss-lara-fran-larda-en-fackbok-och-en-forfattare