The Natural GLP-1 Alternative

In this episode of Hormone Heroines, we sit down with Sarah Kennedy, founder and CEO of Calocurb, to explore the science behind natural GLP-1 activation and appetite regulation.

Sarah explains how our bodies naturally produce GLP-1 and other appetite-regulating hormones after eating, why these signals can become less effective with age and modern eating habits, and how prescription GLP-1 medications differ from the body's normal physiology.

We discuss how Calocurb was developed through more than 16 years of New Zealand government-funded research and uses a proprietary bitter hop extract to stimulate bitter taste receptors in the intestines, encouraging the body's own release of GLP-1, CCK, and PYY. Sarah reviews the early clinical research showing increased appetite-regulating hormone release and reduced calorie intake, as well as an upcoming larger clinical trial evaluating weight loss and body composition that had not yet been published at the time of this interview.

The conversation also explores how clinicians are using Calocurb for individuals seeking a natural option, those unable to tolerate GLP-1 medications, and patients transitioning off prescription GLP-1 therapy. Throughout the episode, Sarah and the hosts emphasize that appetite support works best when combined with healthy nutrition, regular movement, and sustainable lifestyle changes.

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About the Guest:

Sarah Kennedy is the founder and CEO of Calocurb, a New Zealand company focused on developing evidence-based, plant-derived solutions for appetite regulation and weight management. Working alongside research supported by the New Zealand government, Sarah has helped commercialize Calocurb after more than 16 years of scientific development. She is passionate about translating nutritional science into practical tools that support healthy weight management through the body's natural appetite-regulating mechanisms.

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10% off discount code: BLOSS10
https://www.calocurb.com/BlossLong
Calocurb is a clinically proven, plant-based nutraceutical that reduces hunger by 30%, cravings by 40% and calorie intake by 18%. All natural, Calocurb contains no stimulants, nothing synthetic and is caffeine-free, vegan and certified non-GMO. The active ingredient in Calocurb is a unique extract from the hops flower developed and clinically tested by leading New Zealand scientists from Plant & Food Research over 14 years and with $30m investment. Calocurb gets to work in just one hour so you can feel full faster.

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The Hormone Heroines

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