unPAUSED with Dr. Mary Claire Haver21 Juli

The Ovary’s Job Doesn’t End at Menopause: A Top Neuroscientist Explains

In this episode of unPAUSED, Dr. Mary Claire Haver talks with Dr. Jennifer Garrison, a neuroscientist and entrepreneur, about why the ovary should never have been labeled a purely reproductive organ. Dr. Garrison explains that ovaries function like a second brain in the body, sending and receiving chemical signals to nearly every tissue system including the heart, bones, brain, immune system, and metabolism. She walks through her research on the hypothalamus and the brain ovary signaling network, describing how inflammation in this part of the brain may be one of the earliest drivers of aging across the whole body.

The conversation covers why the ovary ages roughly two and a half times faster than the rest of the body, a gap that helps explain the health span difference between women and men. Dr. Garrison and Dr. Haver discuss how poor ovarian function shows up across a woman's life, not only at menopause, contributing to conditions like polycystic ovarian syndrome, infertility, early menopause, depression, metabolic disease, and autoimmune disease. They also unpack why autoimmune conditions rise sharply after menopause and why women's immune systems respond differently to viruses than men's.

Guest links:

Jennifer Garrison, PhD (LinkedIn)

Jennifer Garrison (X)

Jennifer Garrison (Bluesky)

Jennifer Garrison (X Prize)
Jennifer Garrison (The Institute)

Books

“The New Perimenopause,” by Dr. Mary Claire Haver

“The New Menopause"⁠ by Dr. Mary Claire Haver

For full show notes, please click here.

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Avsnitt(56)

Menopause Sleep Reset: A Recovery Plan You Can Start Tonight with Dr. Kristen Holmes

In this episode of unPAUSED, Dr. Mary Claire Haver continues her conversation with Dr. Kristen Holmes, Vice President of Performance Science at Whoop and author of the new book Aligned, moving from th...

14 Aug 51min

Menopause and the 3AM Wake Up: What Light, Meal Timing and Hormones Do with Dr. Kristen Holmes

In this episode of unPAUSED, Dr. Mary Claire Haver sits down with Dr. Kristen Holmes, Vice President of Performance Science at Whoop and author of the new book Aligned, to unpack why sleep and circadi...

11 Aug 1h 7min

An ADHD and Menopause Toolkit: What Actually Helps with Dr. Sasha Hamdani

In this episode of unPAUSED, Dr. Mary Claire Haver continues her conversation with Dr. Sasha Hamdani, a board certified psychiatrist and ADHD clinical expert who wrote Self-Care for People with ADHD a...

7 Aug 41min

Brain Fog, Rage, Overwhelm: The ADHD and Menopause Overlap with Dr. Sasha Hamdani

In this episode of unPAUSED, Dr. Mary Claire Haver sits down with Dr. Sasha Hamdani, a board certified psychiatrist, ADHD clinical expert, and author of the forthcoming book Too Sensitive, for the fir...

4 Aug 51min

Menopause Masterclass: When "Normal Labs" Are Lying to You

In this episode of unPAUSED, Dr. Mary Claire Haver delivers a solo masterclass on the lab work every woman in perimenopause, menopause, and post menopause should understand and request from her doctor...

28 Juli 48min

Lift Heavy, Protect Your Brain: Strength, Creatine, and Sauna for Women with Dr. Stacy Sims

In this episode of unPAUSED, Dr. Mary Claire Haver continues her conversation with exercise physiologist and nutrition scientist Dr. Stacy Sims, moving from what does not work to what actually does fo...

17 Juli 42min

Why Women Gain Weight on the Same Diet as Men: Fueling, Fasting, and Biology with Dr. Stacy Sims

In this episode of unPAUSED, Dr. Mary Claire Haver sits down with exercise physiologist and nutrition scientist Dr. Stacy Sims to unpack why so much fitness and diet advice built on male physiology le...

14 Juli 1h 4min