Ep. 39 - I'm All Right, JAK! (feat. Stephen Shaw)

Ep. 39 - I'm All Right, JAK! (feat. Stephen Shaw)

In this episode of Skinflints, we are joined by veterinary dermatologist Dr Stephen Shaw to discuss the role of JAK inhibitors in managing canine atopic dermatitis. Stephen explains the underlying disease process, highlighting the key cytokines involved in itch and inflammation, and how JAK inhibitors provide rapid, broad-spectrum control by blocking these signalling pathways.

The discussion explores how treatment should be tailored to each individual dog, considering disease severity, secondary infections and long-term management goals. Stephen also explains the benefits of using JAK inhibitors during food trials, their role alongside other therapies, and practical considerations such as monitoring, vaccination and managing concurrent disease.

The episode concludes by emphasising the importance of evidence-based treatment, informed owner discussions and regular clinical assessment, reinforcing that successful management relies on selecting the right therapy for each patient rather than adopting a one-size-fits-all approach.

This episode is kindly sponsored by MSD Animal Health

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Avsnitt(40)

Ep.40 - The Real Sheep Detective (feat. Stephen D. White)

Ep.40 - The Real Sheep Detective (feat. Stephen D. White)

In this month's episode, Sue, John and Paul welcome Professor & Chief of Service (Dermatology) at UC Davis, Stephen D White to the podcast. Chapter 1: Sheep Skin Detectives (03:09) Sue sets the scope:...

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Episode 38 - Cat.exe Has Stopped Working; FOPS and the Furious Face (Clare Rusbridge)

Episode 38 - Cat.exe Has Stopped Working; FOPS and the Furious Face (Clare Rusbridge)

(00:00:00) John introduces a new episode on Feline Orofacial Pain Syndrome (FOPS) — a baffling condition where cats can flip from calm to frantic self-injury around the mouth and face in seconds.   Ch...

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Episode 37 - Bow Ties and Blink Reflexes (David Williams)

Episode 37 - Bow Ties and Blink Reflexes (David Williams)

Bow Ties and Blink Reflexes: Periocular Perils on SkinFlint   In this month's episode, Sue & John invite a well known vet with his eye on pet eyes - David Williams. (00:00) John opens SkinFlint. Toda...

21 Feb 43min

Episode 36 - Hives, Lesions and Lumps; Urticaria in Horses (Valerie Fadok)

Episode 36 - Hives, Lesions and Lumps; Urticaria in Horses (Valerie Fadok)

Episode Overview Join us as we venture into the stables to explore urticaria in horses - those mysterious swellings that appear seemingly out of nowhere and may disappear just as suddenly. Expert gues...

7 Jan 38min

Episode 35 - Ferrets, Fur and Fun; Taming The Beastmasters (Madonna Livingstone)

Episode 35 - Ferrets, Fur and Fun; Taming The Beastmasters (Madonna Livingstone)

In this month's episode, Sue John and Paul invite exotics guru Madonna Livingstone onto the podcast to discuss general and skin issues in ferrets.   Overview of ferrets as pets:    - Ferrets have been...

29 Nov 202548min

Episode 34 - Short Noses, Big Problems: Lumps, Chins and Comorbidities in Brachycephalics (Laura Buckley)

Episode 34 - Short Noses, Big Problems: Lumps, Chins and Comorbidities in Brachycephalics (Laura Buckley)

Chapter 1 – “Lumps, Not Bugs: Cracking the ‘Sterile’ Case” 03:22 – John welcomes Dr Laura Buckley back for part two on brachycephalic skin disease and tees up two topics: Sterile Granuloma/Pyogranulom...

3 Nov 202536min

Episode 33 - Bulldogs, Pugs and Plenty of Folds; A Deep Dive into Brachy Skin (Laura Buckley)

Episode 33 - Bulldogs, Pugs and Plenty of Folds; A Deep Dive into Brachy Skin (Laura Buckley)

Chapter 1 – Intertrigo: Prevention, Work-Up, and When (Not) to Use Antibiotics (00:11) John introduces the podcast episode and the hosts. (02:39) John welcomes Dr Laura Buckley (Senior Lecturer, Veter...

21 Okt 202543min

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