391: The Kaufmann Protocol — Why We Age and How to Stop It

Dr. Sandra Kaufmann, The Kaufmann Anti-Aging Institute - Dr. Sandra Kaufmann — physician, scientist and athlete — set out to understand aging and fight it with science. This episode is a guided overview of her book, featured with the author's permission: why our cells age (mitochondria, genetic information systems, quality control and maintenance, immunity, and waste management) and the families of anti-aging molecules she reviews (resveratrol, astaxanthin, NAD, curcumin, metformin, melatonin and more) — framed as an informed, individualized approach rather than a quick fix. Key terms: aging, longevity, anti-aging molecules, cellular biology, Kaufmann Protocol.

Study Highlights:
The book maps aging onto cellular causes — declining mitochondria, genetic information systems, cellular quality control and maintenance, immune changes, and waste management — and then reviews the leading molecules and adjuvants that target these pathways. Dr. Kaufmann turns the science into the basis for an informed, personalized plan, stressing that it is not a diet or quick fix and that decisions about supplements should be made together with a physician.

Conclusion:
Aging has identifiable biological drivers, and a science-literate, individualized approach — discussed with a physician — can help people age more deliberately rather than passively. Presented as Dr. Kaufmann's perspective, featured with the author's permission.

Title: The Kaufmann Protocol: Why We Age and How to Stop It
Reference: Kaufmann, S.C. The Kaufmann Protocol: Why We Age and How to Stop It. Jacob Cerny (Ed.), Ross Goldstein (Illus.). Kaufmann Anti-Aging Institute, 2018. ISBN 978-0-692-08904-0.
ISBN: 978-0-692-08904-0

License:
This episode is a guided overview of the book "Why We Age and How to Stop It: The Kaufmann Protocol" by Dr. Sandra Kaufmann, featured and adapted with the kind permission of the author.

Support:
Base by Base – Stripe donations: https://donate.stripe.com/7sY4gz71B2sN3RWac5gEg00

Official website https://basebybase.com

On PaperCast Base by Base you'll discover the latest in genomics, functional genomics, structural genomics, and proteomics.

Episode link: https://basebybase.castos.com/episodes/kaufmann-protocol-why-we-age

QC:
This episode is a guided overview of the book "Why We Age and How to Stop It — The Kaufmann Protocol" by Dr. Sandra Kaufmann, featured with the author's kind permission and reviewed for editorial accuracy.

QC Summary:
- verdict: pass
- review mode: book overview (author-authorized)
- framing: presented as the author's perspective and synthesis
- note: educational content only — not medical advice; decisions about supplements should be made with a physician

Det här avsnittet är hämtat från ett öppet RSS-flöde och publiceras inte av Podme. Det kan innehålla reklam.

Avsnitt(462)

461: Adult Ank3 loss quiets neurons and lowers a myelin protein

Yoon et al., Proceedings of the National Academy of Sciences - ANK3, which encodes the scaffolding protein ankyrin-G, is a major risk gene for bipolar disorder and schizophrenia, yet what it does in a...

24 Sep 24min

460: The lupus variant that also sharpens antiviral defense

Virolainen et al., The American Journal of Human Genetics - A lupus signal on chromosome 11p15 narrows to a coding haplotype in IRF7 that most people in the world carry. This study shows the risk form...

21 Sep 24min

459: Cerebral palsy genetics: 515 candidate genes, evidence for 89

Arterbery et al., The American Journal of Human Genetics - Hundreds of genes have been reported as causes of cerebral palsy, yet there is no agreed model of what a pathogenic variant in a child with C...

13 Sep 24min

458: Somatic or inherited? Reading TP53 risk from shared DNA

MacGregor et al., The American Journal of Human Genetics - Pathogenic TP53 variants found in blood have long been read as inherited Li-Fraumeni alleles, but many turn out to be somatic clones that gre...

10 Sep 25min

457: A deletion that raises Alzheimer risk, a duplication that lowers it

Quenez O et al., The American Journal of Human Genetics - Rare copy-number variants were called from 22,319 exomes covering early-onset Alzheimer disease, late-onset disease and unaffected controls, t...

9 Sep 24min

456: Beyond exons: where heritability hides as traits get more polygenic

Fuhrer J et al., The American Journal of Human Genetics - Across 34 complex traits and disorders, a MiXeR-based framework partitions SNP heritability over 74 functional annotations and finds that exon...

8 Sep 45min

455: Agentic genomics: the bottleneck moves from code to judgment

Corpas M et al., Cell Genomics - A Perspective arguing that autonomous AI agents which discover, configure and chain bioinformatics operations from natural-language instructions have shifted the bottl...

7 Sep 13min

454: Efavirenz retarda a doença priônica mexendo no colesterol do cérebro [PT]

Ali T et al., JCI Insight - Um antirretroviral aprovado para HIV, dado por via oral em microdose, prolongou a sobrevida de camundongos que carregam a proteína priônica humana e foram infectados com pr...

2 Sep 17min