220. Is plant-based dead? Paul Saladino MD on Radical Health Radio

Will an mRNA vaccine save us from COVID? Doubt it, and it certainly won’t save us from the massive amount of metabolic dysfunction that is driving severe COVID outcomes. In this Controversial Thoughts episode I describe recent research with both vaccines (Moderna/Pfizer), what looks good, things we still don’t know, and major potential problems possible in the future. How do you fix metabolic dysfunction? Listen until the end of the video in which I describe a striking interventional study with a carnivore-ish diet! #theremembering

27 Nov 202029min

This stuff is technical but critically important to understanding the possible underlying mechanisms by which excess PUFA may be hurting you. If this is confusing you may want to start with the first episode Peter and I did, all of which are at heartandsoil.co.    Petro Dobromylskyj is a veterinarian, trained at the RVC, London University. He was fortunate enough to intercalate a BSc degree in physiology into his veterinary degree. He was even more fortunate to study under Patrick Wall at UCH, who set me on course to become a veterinary anaesthetist, mostly working on acute pain control. That led to the Certificate then Diploma in Veterinary Anaesthesia and enough publications to allow him to enter the European College of Veterinary Anaesthesia and Analgesia as a de facto founding member. Anaesthesia teaches you a lot. Basic science is combined with the occasional need to act rapidly. Wrong decisions can reward you with catastrophe in seconds. Thinking is mandatory. He stumbled onto nutrition completely by accident. Once you have been taught to think, it's hard to stop. Time Stamps:   0:14:04    Podcast Begins 0:14:46    Last Episode Recap 0:17:20    Why PUFAs drive obesity 0:22:43    Inappropriate insulin sensitivity 0:31:14    Why we have mitochondria 0:41:26    Being right on Q: shaping eukaryotic evolution    https://pubmed.ncbi.nlm.nih.gov/27834740/ 0:44:14    Mitochondrial satiety signaling 0:50:38    The glycerol phosphate shuttle 1:08:54    Reverse electron transport generating ROS 1:13:58    The Krebs cycle explained 1:22:59    Iatrogenic Hyperinsulinemia, Not Hyperglycemia, Drives Insulin Resistance in Type 1 Diabetes as Revealed by Comparison With GCK-MODY (MODY2)    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692813/ 1:23:58    Are carbs the root-cause of metabolic dysfunction? 1:30:31    Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase    https://www.researchgate.net/publication/262529290_Metformin_suppresses_gluconeogenesis_by_inhibiting_mitochondrial_glycerophosphate_dehydrogenase 1:38:47    Metformin (01) Insulinhttps://high-fat-nutrition.blogspot.com/2017/07/metformin-01-insulin.html 1:44:29    Optimizing satiety with saturated fat and glucose 1:49:50    Where to Find Peter    https://high-fat-nutrition.blogspot.com/ 1:50:34    The fates of Pyruvate 1:52:02    Diets could

23 Nov 20201h 58min

If you missed yesterday's controversial thoughts podcast/video, you might also want to check that one out. I had a few ideas I wanted to discuss on COVID after I finished recording and knew I had to do another. The concept of "long COVID" is increasingly discussed today, but I'm not convinced this is anything new. First, it was "healthy" people (sadly) suffering from COVID who were obese or likely had metabolic dysfunction, and I think it's the same issue now. The majority of those with underlying metabolic dysfunction DON'T know they have it, which is why discussions of this are so important.   If you're new here and don't know what I mean by metabolic dysfunction, this might be thought of as insulin resistance, though that terminology is imprecise. Listen to the podcast next Tuesday (Fundamental Health) for part 2 with Peter from Hyperlipid to hear more discussion of this, or listen to the many podcasts I've done discussing it previously.   Take away: Long COVID is an underlying, undiagnosed metabolic illness IMO. Be metabolically healthy.#thremembering

21 Nov 20209min

If you are curious about connections between metabolic dysfunction and the strength of your immune system but don't have time to listen to this video you disappoint me! 🤣 JK! But you should listen to this one and share it with someone in your life who is obese (and likely pre-diabetic) who doesn't think they are at risk of a bad COVID outcome, or maybe they are terrified but don't know what they can do about it other than cowering in their homes and continue eating junk. Nothing changes without a spark. Maybe you showing these ideas to someone will be the spark that saves their life. Or not, which is why I'll keep doing what I'm doing even amidst worsening censorship. Can't hold the truth down forever. #theremembering

20 Nov 202026min

This podcast will likely be censored on YouTube, but the video will be available at heartandsoil.co if this happens. We are only presenting facts in this podcast, but we’ll see what sort of nonsense the “fact checkers” come up with.  This is the second podcast I have done with Ivor on COVID. We’ve also done a podcast on LDL and cholesterol. All of these can be found under the “learn” tab at heartandsoil.co.    Bio: Ivor Cummins BE(Chem) CEng MIEI PMP completed a Biochemical Engineering degree in 1990. He has since spent over 25 years in corporate technical leadership and management positions. His career specialty has been leading large worldwide teams in complex problem-solving activity.  Time Stamps   0:09:08   Podcast Begins 0:11:08   Ivor's predictions came true 0:12:32   The Mainstream covid messaging is missing the mark 0:14:58   Why lockdowns are ineffective 0:18:17   Do masks work? 0:19:51   The Who are science deniers 0:20:54   Do Lockdowns work? 0:25:28   This is a Case-demic, not a pandemic  0:26:08   Why PCR tests are bogus 0:37:07   The WHO redefines the word "pandemic" and positions themselves for profit 0:39:47   What about Sweden? 0:45:28   Herd immunity is the ONLY way forward 0:50:34   Effect of school closures on mortality from coronavirus disease 2019: old and new predictions   https://www.bmj.com/content/371/bmj.m3588 0:51:15   A country level analysis measuring the impact of government actions, country preparedness and socioeconomic factors on COVID-19 mortality and related health outcomes   https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(20)30208-X/fulltext 1:04:07   Some thoughts on vaccines 1:13:49   We'll never conquer nature 1:15:42   The invisible blood of the "pandemic" nonsense 1:25:42   Is metabolic health a risk factor for covid-19 1:27:12   Is metabolic health a risk factor for covid-19DEAN 1:32:24   Metabolic Syndrome and COVID-19 Mortality Among Adult Black Patients in New Orleans   https://care.diabetesjournals.org/content/early/2020/08/18/dc20-1714 1:32:56   COVID-19: underlying metabolic health in the spotlight   https://www.thelancet.com/journals/landia/article/PIIS2213-8587(20)30164-9/fulltext 1:45:12   The mainstream

16 Nov 20202h 1min

Last week’s Controversial Thoughts was on The Carnivore Diet for Beginners. This week, I wanted to discuss the spectrum of plant toxicity a bit more. Thinking about this from the perspective of plants makes it a whole lot easier. Plants don’t want their seeds (nuts, grains, seeds, legumes), leaves, stems, or roots eaten. Avoid these foods while focusing on the least toxic parts of plants (fruit- sweet and non-sweet) while making meat and organs the centerpiece of your diet and you will thrive. #theremembering

13 Nov 202017min

Part 1 of “Is a Carnivore Diet the Real Paleo Diet” is my friendly debate with Loren Cordain et al., which can be found here. Nora Gedgaudas is a widely recognized expert on the “Paleo diet”. She is the author of the international best-selling book, Primal Body, Primal Mind: Beyond the Paleo Diet for Total Health and A Longer Life. She maintains a private practice in Portland, Oregon as both a Board-Certified nutritional consultant and a Board-Certified clinical Neurofeedback Specialist. Her latest book Primal Fat Burner was released in January 2017 by Simon & Schuster (Atria).   Time Stamps:   0:09:58   Podcast Begins 0:10:58   How Nora became a godmother of paleo 0:19:51   Why Primal? 0:24:49   Nora's time with the wolves 0:29:42   Humans are fat-eaters  0:32:28   Humans are designed to eat meat  0:38:34   Animal fat: the most precious nutrient 0:47:40   The protein sweet spot 0:52:22   Why you want cyclic mTOR activation 1:01:32   Prioritizing your digestive health 1:09:36   Dietary diversity does not equate to alpha diversity 1:14:49   Fiber is not required for a healthy gut 1:17:00   High fat or high protein? 1:27:52   Where to Find Nora Gedgaudas 1:29:38   Nora's Radical primitive skills Heart & Soil: www.heartandsoil.co    Cinder: cindergrill.com/pages/carnivoremd,   Chilipad/ Ooler: https://www.chilitechnology.com//CarnivoreMD   White Oak Pastures: www.whiteoakpastures.com code CarnivoreMD for 10% off first order Belcampo: www.belcampo.com code CarnivoreMD for 20% off

9 Nov 20201h 36min

Most of my podcasts are pretty detailed and technical. I wanted to do a high level discussion of how to think about a Carnivore Diet and how to get started with this. There’s lots more info about this at heartandsoil.co on the about us page. The basics, eat well raised animal foods from nose to tail including organs and connective tissue. You can include less toxic plant foods if you’d like to depending on your goals. Welcome to #TheRemembering   Check out heartandsoil.co if you need more nose to tail nutrition in your life. The JRE show notes are there as well.

6 Nov 202013min