EP 92 Integrins: The Conversation Between Cells and Fascia

Cells are constantly receiving information not only through chemical messengers such as hormones, neurotransmitters, and growth factors, but also through their physical environment. In this episode, we explore integrins: specialized cell-surface receptors that help link the extracellular matrix to the cell’s internal scaffolding. I discuss how integrins participate in adhesion, movement, cellular organization, and mechanosensing and why a cell’s local environment, including matrix composition, structure, stiffness, and loading, can influence its behavior. All this gives us one more reason to keep fascia healthy!

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References mentioned:

Anderson, L. R., Owens, T. W., & Naylor, M. J. (2014). Structural and mechanical functions of integrins. Biophysical reviews, 6(2), 203–213. https://doi.org/10.1007/s12551-013-0124-0

Fagerholm S. C. (2022). Integrins in Health and Disease. The New England journal of medicine, 387(16), 1519–1521. https://doi.org/10.1056/NEJMcibr2209679

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Avsnitt(92)

EP 91 Thermography and Fascia-Informed Care: What Can Skin Temperature Tell Us?

EP 91 Thermography and Fascia-Informed Care: What Can Skin Temperature Tell Us?

Thermography is increasingly marketed as a painless, noninvasive way to look at what may be happening in the body, but what can it actually tell us? In this episode, I explore infrared thermography th...

14 Sep 30min

EP 90 An Encore and an Opportunity for You

EP 90 An Encore and an Opportunity for You

In this episode, I'm replaying one of the most popular topics from EP 78. Most of us can improve on our understanding of stress and how it affects the body. The article by Huston (2022) presents a com...

17 Aug 40min

EP 89 Is Fascia a System? Not everyone thinks so. What do you think?

EP 89 Is Fascia a System? Not everyone thinks so. What do you think?

Each discipline operates from different rules and definitions. A system can be defined as "a set of things working together as parts of a mechanism or an interconnecting network; a complex whole". So,...

20 Juli 14min

EP 88 Self-Treatment and Chronic Hand Pain (Altahif & Davis, 2026)

EP 88 Self-Treatment and Chronic Hand Pain (Altahif & Davis, 2026)

This episode explores lessons from Altahif and Davis (2026), a survey of hand therapy practitioners on self-management strategies for clients with chronic hand pain. The survey examined what clients w...

15 Juni 38min

EP 87 OTs Don’t Cut: We Get Curious and Ask Questions

EP 87 OTs Don’t Cut: We Get Curious and Ask Questions

In this episode I share a real‑life phone call from a very young potential client who reached out about a tongue‑tie release and frenectomy, expecting a quick surgical solution. Instead of rushing to ...

1 Juni 20min

EP 86 The Future of Fascia: A Scoping Review Yields Research Directions

EP 86 The Future of Fascia: A Scoping Review Yields Research Directions

In this episode of The Fascia Informed Therapist, we unpack a recent scoping review on the future of fascia research and translate its findings into practical clinical direction for occupational thera...

18 Maj 22min

EP 85 Lessons from a New Client: We see the body differently.

EP 85 Lessons from a New Client: We see the body differently.

In this episode I review the case of a new client who really made it hit home how we, as fascia-informed practitioners see the body differently. We engage with our clients differently and it gives the...

4 Maj 27min

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