226. Eating meat reverses aging

Dr. James DiNicolantonio, is a Doctor of Pharmacy and a cardiovascular research scientist. A well-respected and internationally known scientist and an expert on health and nutrition, he has contributed extensively to health policy and has testified in front of the Canadian Senate regarding the harms of added sugars. He serves as the associate editor of the British Medical Journal’s Open Heart, a journal published in partnership with the British Cardiovascular Society, and is on the editorial advisory boards of several other medical journals. Dr. DiNicolantonio is the author or coauthor of over 250 publications in the medical literature. He also is the author of three bestselling health books, The Salt Fix, Superfuel and The Longevity Solution. You can follow him on Instagram and Twitter @drjamesdinic and on Facebook at Dr. James DiNicolantonio. You can visit his website at drjamesdinic.com.   Time stamps:   10:25 Electrolytes. How much salt did we have evolutionary ?  13:05 How much salt do humans need? 16:00 Can we go too high on salt consumption? 21:20 Magnesium. 24:45 Insulin Resistance and sodium  27:45 Kidney function. Bumps in BUN and Creatinine. 29:00 How to measure for magnesium deficiency. 31:00 Vitamin C 39:15 Ideal vitamin C intake for humans. 59:45 Concerns of higher vitamin C intake. 1:02::25 Vitamin C and people with G6PD deficiency. 1:07::05 Cadmium and kidneys. 1:11:27 Chlorella and pollutant binding. 1:13:15 Fiber and dioxins. 1:16:35 James' diet. Is it cheaper to eat plant foods? 1:19:35 Molecular xenohormesis. 1:24:30 Are plants beneficial ? 1:32:30 The fear of glucose spikes. 1:34:35 Resistant starch. 1:39:14 Where to find James and the most radical thing he's done recently. Ancestral Supplements https://ancestralsupplements.com/   Code SALADINOMD on the shopify site to receive 10% off.   Use the code CARNIVOREMD at www.whiteoakpastures.com all month for 10% off your order!   JOOVV: www.joovv.com/paul INSIDER: carnivoremd.com   My contact information:   Book: www.thecarnivorecodebook.com   PATREON: <a href= "https://www.you

21 Jan 20201h 44min

James W. Clement is a lawyer and entrepreneur turned research scientist who has devoted the last two decades to understanding the science of life extension. He is best known for his Supercentenarian Research Study, which he started in 2010 with Professor George M. Church of Harvard Medical School and has received international press coverage. Through worldwide scientific collaborations and in his own laboratory, James focuses on advancing cutting-edge biomedical discoveries. He is the founder of the nonprofit Betterhumans biomedical research organization. Led by a collection of high-profile researchers, the organization focuses on bringing cutting edge scientific discoveries from the lab to the clinic. Clement was the 12th person in the world to have his whole genome sequenced and is Personal Genome Project participant #145   Time Stamps: 10:10 Start of podcast  10:50 What type of research is James doing and how does it relate to aging? 12:55 Compression of morbidity.  23:50 Feedlot meat and processed foods (23:50-24:35) 25:50 Super centenarian studies. 28:25 Observations on what super centenarians have in common. 31:40 Laron Dwarfs and IGF1 (22:00-22:45) 33:30 Should we over stimulate IGF1? 37:10 Measuring IGF1 39:40 Blue Zones and centenarian diets 42:50 Intermittent Hypoxia  46:40 Over fasting, finding a good balance. 51:40 Environmental hormesis  52:50 Okinawans  55:40 Confounding variables. 1:00:25 mTor/ketosis and glycogen depletion in the liver.  1:03:40 Animal based diets and intermittent ketosis. 1:06:10 James' thoughts on the carnivore diet. 1:10:55 Lack of nutrients in a plant based diet. 1:12:30 Benefits of prolonged ketosis in morbidly obese. 1:16:10 Protein sparing modified fast benefits. 1:20:10 Calorie restricted pure vegan diet. 1:22:00 Dexa scan. 1:25:50 James's insulin levels. 1:27:40 AGEs (advanced glycation end products) 1:34:10 Stress and glucose levels. 1:38:50 Does too much protein harm the kidneys? 1:45:10 Protein cycling. 1:46:34 Occasional long term fasting benefits. 1:47:35 Loma Linda sperm quality. 1:49:40 Carnivore diet for longevity. 1:52:20 Issues with studies comparing meat eaters vs. non meat eaters. 1:54:00 The most radical thing James has done rece

14 Jan 20201h 59min

Dr. Gabrielle Lyon is a functional medicine physician specializing in Muscle-Centric Medicine. She leverages evidence-based medicine with emerging cutting-edge science to restore metabolism, balance hormones and optimize body composition. Dr. Lyon has brought unparalleled results to her patients with personalized advanced nutritional interventions, metabolic and genetic testing, and behavioral action plans that leave no stone unturned. When you work with Dr. Lyon, you will enter into a partnership that will bring you long-term success and life-changing breakthroughs in every aspect of your life. She will help you gain clarity and a deeper understanding of what aspects of your body, mind and health need healing—and then customize a strategic action plan to put you on the healing path so you can get your life back. Dr. Lyon attended the Arizona College of Osteopathic Medicine and is board-certified in Family Practice. She also completed her research fellowship in Nutritional Science and Geriatrics at Washington University in St. Louis. Prior to her foray into medicine, Dr. Lyon was a national semifinalist in Fitness America, a professional fitness model and nationally ranked figure competitor. Dr. Lyon's ongoing work is focused on metabolism, muscle, and body composition optimization. As a nationally recognized authority, Dr. Lyon is a regular speaker, sought after expert and educator. Dr. Lyon sees patients in New York City.   Time Stamps:    8:31 Start of podcast 9:28 Gabrielle's backstory. 10:26 Protein requirements.  11:31 Why to eat enough protein. 12:56 Why plant proteins are problematic for older people. 15:17 Muscle protein synthesis thresholds. 19:01 Leucine in plants. High quality proteins.. 19:11 What is a high quality protein? 21:31 Dangers of limiting your protein intake as you age. 23:31 Muscle loss as you age. 24:31 mTor. 26:11 Is there legit evidence that excess protein can lead to cancer? 28:54 The anti-animal narrative. 29:11 Mental flexibility. 31:11 The false narrative of mTor and cancer. 32:49 Difference between protein and carbohydrate insulin stimulating. 35:54 Gluconeogenesis  37:54 Gabrielle's take on the ketogenic diet. 42:01 Cortisol triggering. 44:54 Protein Sparing Fast. 46:41 Why women fail on a ketogenic diet. 48:16 How do some people do well on plant based diets? 51:08 The dishonesty and biases of TH Chang  55:54: Gabrielle's time at Washington University  57:16 Neuro cognitive testing. B12 and b

7 Jan 20201h 27min

Dr Jaime Seeman is a board certified Obstetrician and Gynecologist practicing in Omaha, Nebraska. Born and raised in the state she played collegiate softball for the Cornhuskers. She has a Bachelor of Science degree in Nutrition, Exercise and Health Sciences. She then went on to graduate from medical school and completed her OBGYN residency at The University of Nebraska Medical Center. She currently is in private practice at Mid City OBGYN offering a full range of services in obstetrics, gynecology, robotic surgery and primary care. She is a fellow in Integrative Medicine at The University of Arizona School of Medicine. She is a board certified ketogenic nutrition specialist through The American Nutrition Association. She has a passion for fitness, preventative medicine and ketogenic therapy not only in her medical practice but in her own life. She is married to her husband Ben, a police Sergeant and has three young daughters.  Time Stamps: 6:59 Start of the Podcast 7:44 Jaime's story  11:44 Athletes and nutrition  13:24 When did Jamie become insulin resistant/low carb pushback? 18:49 Jamie's vegan/carnivore experiments and postprandial glucose.  20:29 Blood Sugars on carnivore/keto/vegan. 27:59 Was Jaime eating junk food before going keto? 31:33 What is Jaime eating ? 33:14 Hormones on a ketogenic/carnivore diet(women). 46:59 Estrogen dominance  54:29 Methylation. 57:14 If healthy do we need DIM supplements? 1:01:19 What causes high beta glucuronidase? 1:02:59 Thyroid. Do we need carbs for a healthy thyroid? 1:13:29 Postprandial rise in insulin when you eat protein. 1:19:34 How to fix estrogen dominance. 1:23:14 Troubleshooting for hormones  1:31:19 Is low carb safe during pregnancy? 1:42:59 Where to find Jamie.  1:43:44 The most radical thing Jaime has done recently. Dr. Seeman’s contact information:   www.doctorfitandfabulous.com Instagram: @doctorfitandfabulous Ancestral Supplements https://ancestralsupplements.com/   Code SALADINOMD on the shopify site to receive 10% off.   Use the code CARNIVOREMD at www.whiteoakpastures.com all month for 10% off your order!   JOOVV: www.joovv.com/paul INSIDER:

31 Dec 20191h 48min

Dr. Will Cole, leading functional-medicine expert, consults people around the world via webcam and locally in Pittsburgh. He specializes in clinically investigating underlying factors of chronic disease and customizing health programs for thyroid issues, autoimmune conditions, hormonal dysfunctions, digestive disorders, and brain problems. Dr. Cole was named one of the top 50 functional-medicine and integrative doctors in the nation and is a health expert and course instructor for the world’s largest wellness brands such as mindbodygreen and goop.   Dr. Cole’s contact information:    www.drwillcole.com Instagram: @drwillcole Ancestral Supplements https://ancestralsupplements.com/   Code SALADINOMD on the shopify site to receive 10% off.   Use the code CARNIVOREMD at www.whiteoakpastures.com all month for 10% off your order!   JOOVV: www.joovv.com/paul INSIDER: carnivoremd.com   My contact information:   Book: www.thecarnivorecodebook.com   PATREON: https://www.patreon.com/paulsaladinomd   SOCIAL MEDIA  Instagram: @carnivoremd Website: carnivoremd.com Twitter:@carnivoremd  Facebook: Paul Saladino MD email: drpaul@carnivoremd.com

24 Dec 20191h 20min

These two are truly amazing individuals!  Alyse is a former raw vegan who gathered a following of over 1 million people on YouTube and Instagram by sharing her message of positivity and self love. She received significant criticism from the vegan community earlier this year when she announced that she had begun eating meat and felt much better because of it! She is now thriving on a carnivore-ish diet and was recently featured on Good Morning America telling her story. Tim is a world champion parkour (free running) athlete who experienced significant decline in his health after eating a vegan diet for 6 years, and has similarly found much better health since including meat in his diet. He was filmed for the Game Changers movie but asked to be taken out after his health suffered. Can we please get James Wilks to comment on that???   Alyse contact info: Ig/twitter: @alyseparkerr Tim contact info: Ig/twitter@humantimothy Ancestral Supplements https://ancestralsupplements.com/   Code SALADINOMD on the shopify site to receive 10% off.   Use the code CARNIVOREMD at www.whiteoakpastures.com all month for 10% off your order!   JOOVV: www.joovv.com/paul INSIDER: carnivoremd.com   My contact information:   Book: www.thecarnivorecodebook.com   PATREON: https://www.patreon.com/paulsaladinomd   SOCIAL MEDIA  Instagram: @carnivoremd Website: carnivoremd.com Twitter:@carnivoremd  Facebook: Paul Saladino MD email: drpaul@carnivoremd.com

17 Dec 20191h 25min

Did James Wilks win the debate with Chris Kresser in defense of the Game Changers? Not a chance. Listen to Brian I break this one down in detail as we illustrate how he fell far short of his goal while mis representing data and using shady tactics to make Chris look bad. And guess what? I know how to read a forest plot!  Brian Sanders is the host of the Peak Human podcast and the man behind the anticipated movie Food Lies- a film examining human nutrition, evolution and regenerative agriculture.    Time Stamps:  [12:20] Wilks complains how the meat industry research is largely funded by interest groups, but this is the case with all industries [14:40] Dairy products and cancer association  [18:45] James Wilks completely misinterpreted the Dairy Product Consumption and Prostate Cancer RIsk in the United States  [16:20] The issue with epidemiological studies  [20:19] Does dairy cause inflammation? [24:50] Dairy has actually been proven to have health promoting components [26:25] Wilks falsely claims that Richard Wrangham, British primatologist and Harvard Anthropologist, believes that ancestors were primarily plant eaters throughout evolution [29:20] The reliance or sudden ability to get meat allowed our brains to grow [38:40] Wilks claims that meat consumption causes inflammation [53:50] Does a high protein diet cause kidney problems? [55:02] High protein does not cause problems with bone density [56:50] Heme iron and N-nitroso compounds  [1:08:30] If red meat is so bad for you why do some cultures live longer while eating lots of meat? [1:09:10] Meat intake and cause-specific mortality: a pooled analysis of Asian prospective cohort study  [1:10:25] Athletes and carbohydrates  [1:17:45] Forest Plots  [1:19:00] Vitamin B12 in lake water [1:22:40] Vitamin B12 from unwashed vegetables [1:24:03] Vitamin B12 supplements and cattle [1:26:58] James claims it’s because of the pesticides that the soils are depleted but this is not true  [1:28:17] Wilks brings up a point about omnivores and how some are deficient in B12 [1:30:22] Fiber and the microbiome  [1:31:45] Meat and inflammation   [1:34:02] Magnitude and timing of the postprandial inflammatory response to a high-fat meal in healthy adults: a systematic review [1:37:45] Vegetables, inflammation, and oxidative stress <span

10 Dec 20192h 30min

Stan Efferding is an IFBB Professional bodybuilder and World Record Holding Powerlifter. He is one of only 10 men in the world to ever total over 2,300 pounds raw in competition. Stan holds the title as the World’s Strongest Bodybuilder. Stan studied Exercise Science at the University of Oregon and has been training high school, collegiate, and professional athletes for over 25 years. Stan conducts seminars all over the country for various sports and nutrition and training techniques. He has appeared in many magazines and writes for Muscular Development, Flex Magazine and Power Magazine.Stan is also a successful entrepreneur having built three different start-up businesses into multi-million dollar companies.   Time Stamps Start of Podcast: 5:28 6:28 Stan's story  11:28 Importance of maintaining muscle mass  14:58 Biggest muscle building pitfalls. 16:58 Introducing Damon 17:48: Hafþór Björnsson 24:38 Paul's thoughts on insulin resistance and choline. 27:28 Cholesterol myth  28:58 Calcium  33:28 The Samoa indigenous diet. 36:48 The issues with the combination of fats and carbohydrates in the diet.  39:28 Seed oils. 43:28 Salts 47:58 muscle "pump" 48:58 Keto Adaptation for greater athletic performance. 55:38 Muscle glycogen on a keto diet. 1:00:28 The Carnivore diet for strength athletes.  1:01:58 Protein requirements for performance 1:05:28 Protein quality. 1:07:58 "Hard gainers" 1:17:58 Protein sparing modified fasting. 1:21:28 Aerobic activity requirements. 1:31:28 Problem with oils and rendered fats  1:35:28 Where to find Stan and Damon  1:36:58 The most radical things Stan and Damon have done recently.  Stan’s contact info:   www.stanefferding.com Instagram: @stanefferding Ancestral Supplements https://ancestralsupplements.com/   Code SALADINOMD on the shopify site to receive 10% off.   Use the code CARNIVOREMD at www.whiteoakpastures.com all month for 10% off your order!   JOOVV: www.joovv.com/paul INSIDER: carnivoremd.com   My contact information:

3 Dec 20191h 42min