Professor Tim Spector - Perimenopause Mood Swings? Fix Your Gut First (3 Simple Steps)

Prof. Tim Spector and I talk about gut health, mood, inflammation and fermented foods in perimenopause, and the three diet changes he recommends to start today. Microbiome pioneer, ZOE co-founder and Good Mood Food author Prof. Tim Spector explains why midlife mood changes are not psychosomatic: shifting hormones alter your gut microbes, which changes the inflammation and metabolic signals reaching your brain through the vagus nerve. He shares why serotonin was never the real lever, why inflammation and stable metabolism are, and why people in ZOE’s studies report better mood and energy within two weeks of changing their diet. His three changes: 30 plants a week, three fermented foods a day and an overnight gut rest. We also cover ultra-processed food, protein versus fiber, HRT and dementia risk. WHAT YOU’LL LEARN - How perimenopause changes your gut and your mood - Why inflammation matters more than serotonin - Which ultra-processed foods to cut first - His three gut changes to start today TIMESTAMPS 00:00 Intro: Is Perimenopause Changing Your Gut and Your Mood? 07:20 Mood and Energy Lift Within Two Weeks of Changing Your Diet 09:32 How Shifting Hormones Change Your Gut Microbes 13:34 Why Serotonin Was the Wrong Target, and What Replaces It 19:07 30 Plants a Week, Gut Health and Dementia Risk 23:40 The Best Fermented Foods (and Is Cheese Good for You?) 30:32 Ultra-Processed Food, Diet Coke and What to Ignore on a Label 39:31 Protein vs Fiber: Why Chasing Protein Can Backfire 40:31 Diet, HRT and Exercise: What Each Does to Your Microbiome 45:39 Organic Food, Pesticides and What Actually Matters 48:48 His 3 Gut Changes to Start and 3 Things to Stop VALUABLE RESOURCES - Follow Prof. Tim on Instagram: https://www.instagram.com/tim.spector/ - Want to see what your gut microbes are doing? Try ZOE’s app and gut test: https://zoe.com/ - Explore Prof. Tim’s books, research and latest work: https://www.tim-spector.com/ - Prof. Tim’s new book has over 100 recipes, packed with plants and ferments, designed to lift your mood: https://www.amazon.co.uk/Good-Mood-Food-friendly-bestselling/dp/1787336476 ABOUT THE GUEST Tim Spector, MD, is Professor of Epidemiology at King’s College London and co-founder of ZOE, the nutrition science company leading the gut health revolution. He is the bestselling author of The Diet Myth, Spoon-Fed, Food for Life, Food for Life Cookbook and Ferment. With a focus on cutting-edge science, and honoured with an OBE for his impactful work in fighting Covid-19, Tim stands at the forefront of his field. The original pioneer of microbiome research, he is among the top 100 most-cited scientists in the world.