GLP-1 Drugs... Are They Destroying Muscle? — What Semaglutide, Tirzepatide & Retatrutide Data Actually Shows

GLP-1 Drugs... Are They Destroying Muscle? — What Semaglutide, Tirzepatide & Retatrutide Data Actually Shows

A clinical deep dive into the muscle loss problem on GLP-1 medications. Semaglutide, tirzepatide, and the investigational triple agonist retatrutide all produce remarkable weight loss — but clinical trial data shows that a significant fraction of that loss is lean body mass, not fat. This episode covers the mechanism behind GLP-1-induced muscle wasting, the body composition data from STEP 1 and SURMOUNT trials, who carries the highest risk, and where the next generation of obesity pharmacology — bimagrumab combinations, pemvidutide, and retatrutide's glucagon receptor pathway — is trying to solve the problem. For clinicians, patients, and anyone paying attention to where obesity medicine is actually going.

This podcast is for informational purposes only and is not medical advice.

Det här avsnittet är hämtat från ett öppet RSS-flöde och publiceras inte av Podme. Det kan innehålla reklam.

Avsnitt(66)

The Secretome Explained: Could Cellular Signaling Transform Medicine?

The Secretome Explained: Could Cellular Signaling Transform Medicine?

True-Sciences.com use code Pep20 for 20% off your first order What if some of the most important discoveries in regenerative medicine come not from replacing damaged cells, but from understanding how ...

11 Nov 16min

Monkeys Got Shredded On Peptides?!!

Monkeys Got Shredded On Peptides?!!

Weight loss is not the same thing as fat loss. A 2025 monkey study combining semaglutide with experimental myostatin and activin A antibodies raised the possibility of protecting lean mass while losin...

9 Nov 12min

Where Do Peptides Fit in Pain and Recovery? | Dr. Hany Demian

Where Do Peptides Fit in Pain and Recovery? | Dr. Hany Demian

True-Sciences.com use code Pep20 for 20% off your first order Dr. Hany Demian joins John Garrett for a conversation about chronic pain, injury recovery, regenerative medicine, and where peptides may f...

4 Nov 1h 5min

BPC-157 Update: HHS Policy, Human Evidence & WADA Status

BPC-157 Update: HHS Policy, Human Evidence & WADA Status

BPC-157 is back in the compounding-policy conversation—but what does HHS's new notice actually change, and what does the human evidence show? In this revisit, John Garrett looks at BPC-157's proposed ...

2 Nov 19min

Beyond Stem Cells: Secretomes, Cellular Repair & Longevity | Sanjiv Lal

Beyond Stem Cells: Secretomes, Cellular Repair & Longevity | Sanjiv Lal

What if the future of regenerative medicine isn't just about stem cells—but the biological messages those cells send? In this episode of Peptides Explained, John Garrett sits down with Sanjiv Lal, fou...

28 Okt 1h

CJC-1295 Deep Dive: What the Human Evidence Actually Shows

CJC-1295 Deep Dive: What the Human Evidence Actually Shows

True-Sciences.com Use Code Pep20 for 20% off. A careful look at CJC-1295: the growth-hormone pathway, the distinction between DAC and no-DAC naming, what small human studies measured, the terminated P...

26 Okt 14min

The Silent Killer in Your Kitchen? Seed Oils, Inflammation & What to Cook With Instead with Cherie Calbom

The Silent Killer in Your Kitchen? Seed Oils, Inflammation & What to Cook With Instead with Cherie Calbom

Seed oils may be hiding in more of your everyday foods than you realize. In this episode of Peptides Explained, host John talks with Cherie Calbom, MS—known as the Juice Lady—about seed oils, cooking ...

21 Okt 44min

Retatrutide: Is It Time to Panic? Lilly's Lawsuits, the Science, and What Happens Next

Retatrutide: Is It Time to Panic? Lilly's Lawsuits, the Science, and What Happens Next

Eli Lilly is taking legal action against businesses selling products labeled retatrutide. What do the lawsuits actually establish—and what don't they? John Garrett separates pending legal allegations ...

19 Okt 13min

Populärt inom Hälsa

husmodern-med-amanda-schulman
somna-med-henrik
inga-beiga-morsor
rss-bara-en-till-om-beroende-medberoende
rss-jossan-nina
rss-viktmedicinpodden
not-fanny-anymore
sexnoveller-deluxe
angestpodden
sova-med-dan-horning
rss-ronden
rss-hos-psykologen
rss-vuxna-pa-latsas
sa-in-i-sjalen
rss-basta-livet
johannes-hansen-podcast
tyngre-traningssnack
till-sangs
rss-traningsklubben
rss-lyckopodden