Universal flu vaccine; Science games; AllTrials; Penguin camera

Universal flu vaccine; Science games; AllTrials; Penguin camera

Influenza causes up to five million cases of severe illness and half a million deaths globally every year. Yet, as Adam Rutherford finds out, our current vaccination strategy is a seasonal game of chance, based on guessing the strain that will appear next. Research published this week in Science Translational Medicine, by a team from Mount Sinai Hospital in New York, offers hope for a universal flu vaccine, based on newly discovered antibodies.

Earlier this week, a game to help combat ash dieback was launched on Facebook, called Fraxinus. Reporter Gaia Vince looks at the growing trend for using games to solve scientific problems. Is this new way of gathering and analysing data changing the way science is done?

Currently half of all clinical trials are not published worldwide. Adam talks to Ben Goldacre, author of Bad Pharma, about his new campaign 'AllTrials', which aims to change that.

Finally this week, physicist Peter Barham shows us his instrument - a spy camera system that he's designed to recognise penguins.

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Rock traces of life on Mars, Desert fireball network, Gut microbes and Parkinson's Disease, Science Museum's maths exhibition

Rock traces of life on Mars, Desert fireball network, Gut microbes and Parkinson's Disease, Science Museum's maths exhibition

Could rocks studied by the Mars rover Spirit in Gusev Crater in 2007 contain the hallmarks of ancient life? Geologist Steve Ruff of Arizona State University talks about what he found in hot springs in Chile which begs that question. He says the evidence is intriguing enough for NASA to send its next and more sophisticated Mars robot back to the same spot on the Red Planet in 2020.Adam also talks to Phil Bland of Curtin University in Australia - one of the creators of the Desert Fireball Network - an array of automated cameras across Australia, built to locate where shooting stars land as meteorites and also pinpoint from where they came in the solar system. Boosting the chances of collecting these meteorites and knowing their space origins should helps us to better understand how the Earth and other planets formed 4.5 billion years ago.There's new compelling evidence that microbes in the gut play a role in the development of Parkinson's disease. Tim Sampson of Caltech in the US outlines his experiments which raise this possibility and Patrick Lewis, another Parkinson's researcher at the University of Reading, puts the new findings into a wider context.Adam takes a tour of the spectacular new mathematics gallery at the Science Museum in London. The Winton Gallery's exhibited objects and design by the celebrated architect Zaha Hadid focusses on mathematics in the real world. Adam's guide is lead curator David Rooney.

8 Dec 201636min

Alzheimers research, Lucy in the Scanner, Smart bandages, From supernovae to Hollywood

Alzheimers research, Lucy in the Scanner, Smart bandages, From supernovae to Hollywood

Alzheimers disease is now the leading cause of death in the UK, but there are as yet no treatments to halt or reverse it. There was huge disappointment last week when the drug company Eli Lilly announced that a large, phase 3 clinical trial had failed to show any benefit to mild dementia sufferers from its antibody therapy, solanezumab. So where does this leave our basic understanding of biology of Alzheimers disease and how we might most effectively treat or cure it? Adam Rutherford talks to Alzheimers researcher Tara Spires-Jones of the University of Edinburgh.Also in the programme: The skeleton of the world's most famous fossil, Lucy, has received a body scan which revealed she spent a considerable portion of her life climbing trees. Researchers at the University of Bath are making smart bandages for burns patients which glow when their wounds become infected. Adam also talks to the astrophysicist who gave up studying exploding stars to apply his maths to Hollywood stars in the movie business.

1 Dec 201633min

Predator bacteria therapy, New money for UK science, Stick-on stethoscope, Taming fears in the brain scanner

Predator bacteria therapy, New money for UK science, Stick-on stethoscope, Taming fears in the brain scanner

Bdellovibrio is a small bacterium which preys and kills other bacteria. A team of researchers in the UK has shown in animal experiments that injections of the predator microbe can successfully treat infections. So how close does this take us to Bdellovibrio therapy for human patients and what part might it play in tackling the growing crisis of antibiotic resistance? Adam Rutherford talks to Professor Liz Sockett of the University of Nottingham. The British government has announced that it will be spending an additional £2 billion on research and development by 2020. Commentators say it is the largest hike in public funding for science in a very long time. Dr Sarah Main of the Campaign for Science and Engineering, and Dr Arnab Basu, physicist and CEO of Kromek, discuss the new money and how it would be best used.Also in the programme, materials and electronics engineers in the US have devised a small wearable heart monitor - the size and thickness of a sticking plaster. Adam talks to its lead designer Professor John Rogers of Northwestern University in Chicago. And could phobias be cured without exposure to the thing which frightens people? Dr Ben Seymour outlines an intriguing experiment which involved reading people's thoughts in a brain scanner, which suggests ultimately it may be possible.

24 Nov 201627min

Does Pluto have an ocean, Antarctica's oldest ice, Meat emissions, Swifts fly ten months non-stop

Does Pluto have an ocean, Antarctica's oldest ice, Meat emissions, Swifts fly ten months non-stop

Does the distant dwarf planet Pluto have an ocean beneath its thick crust of ice? It's certainly possible, according to a group of researchers who are analysing the data from the New Horizons Pluto flyby last year. They argue that a deep ocean of water would best explain the position of the great heart shaped depression on Pluto's surface. Adam Rutherford quizzes planetary scientist Francis Nimmo about this new hypothesis.Adam also talks to glaciologist Robert Mulvaney of the British Antarctic Survey, who is now setting off for the frozen south to prospect for the oldest ice in Antarctica. He's part of a European project which aims to drill deep into the ice sheet of East Antarctica and chart the climate and atmosphere history of Antarctica back to 1.5 million years ago. Are grass-fed cattle better for the global climate than cattle fed on grain-based feeds? Dr Tara Garnett of the Food Climate Research Network at Oxford University responds to listeners comments on carbon emissions and diet.Swifts can fly for 10 months non-stop, never touching the ground. Anders Hedenstrom of Lund University discovered this remarkable fact by fitting birds with a tiny electronic backpack which recorded their location and flight activity across a whole year.

17 Nov 201628min

Climate change questions, Animal computer interaction, Sounds and meaning across world's languages

Climate change questions, Animal computer interaction, Sounds and meaning across world's languages

Climate change is in the news this week. The international Paris agreement to curb global temperature rise has just come into effect but President Elect Donald Trump has said he would take the United States out of the process. In BBC Inside Science, Adam Rutherford puts listener's questions and views about climate change to experts, such as the emissions reduction impact of becoming a vegan to a proposed technology to remove carbon dioxide from the planet's atmosphere. Myles Allen and Peter Scarborough of the University of Oxford, and Anna Harper of the University of Exeter are consulted.The programme also visits a lab at the Open University which studies the way animals interact with computer technology. Research includes technology to enable dogs to phone the emergency services if humans get into trouble, and using dogs to detect cancer. Reporter Marnie Chesterton meets researcher Clara Mancini and dogs Ozzie and Tory.Are there commonalities across the world's languages between the sounds in particular words and the meanings of those words? The traditional thinking in linguistics says no. But new research surveying the meaning and sounds of words across 6,000 languages from the Americas, Asia, Europe and Australasia finds otherwise. The 'r' sound is used in words for the colour 'red' all around the world at frequencies much higher than by chance. The case is the same for the words for 'nose' and other parts of the body. Morten Christiansen of Cornell University talks to Adam Rutherford about the research.

10 Nov 201628min

Italy's quakes, Ebola virus, Accidental rocket fuel, China in space

Italy's quakes, Ebola virus, Accidental rocket fuel, China in space

In the past three months, central Italy has been shaken by several large earthquakes. The quake near Norcia on 30th October was the most powerful for decades. In late August, another struck near Amatrice, causing 300 lost lives. Adam Rutherford talks to seismologist Ross Stein about why this part of the Italian peninsula is so prone to shaking, whether there is a pattern in the recent activity and whether the scientists are getting any better at earthquake forecasting.The recent Ebola epidemic in West Africa was the largest and most deadly of its kind so far. More than 11,000 people were killed by the virus. Now two groups of virologists have discovered that early in the epidemic's course, the Ebola virus underwent a genetic change which allowed it to infect human cells more easily. Could this mutation explain the terrible scale of the outbreak of 2013 to 2016?Also in the show, the chemists who are aiming to make ammonia fertiliser production more environmentally friendly but made rocket fuel instead; and the past and future of the Chinese space programme.

3 Nov 201627min

Making mozzies safe with a microbe, CO2 at 400 ppm, Chixculub crater rocks, Why Mars Lander failed

Making mozzies safe with a microbe, CO2 at 400 ppm, Chixculub crater rocks, Why Mars Lander failed

Adam Rutherford meets the Australian scientist behind a radical new technique to prevent mosquitoes from spreading the zika and dengue fever viruses to people. The method involves infecting mosquitoes with a harmless bacterium. The microbe doesn't kill the mosquitoes but stops the viruses multiplying inside them and spreads rapidly through wild mosquito populations. After 15 years of research, the mosquito control method is about to be deployed in large scale trials in urban areas in South America.Also in the programme, the world's atmosphere crosses an iconic threshold as measured by the concentration of the greenhouse gas carbon dioxide: scientists get their hands on the rocks at the centre of the extinction of the dinosaurs: and details emerge of why the European Space Agency's recent Mars lander crashed onto the Red Planet.

27 Okt 201631min

HFC Ban; Human Cell Atlas; Origin of Hunting with Dogs

HFC Ban; Human Cell Atlas; Origin of Hunting with Dogs

Biologists are to begin a 10 year international project to map the multitude of different kinds of cell in the human body. The average adult is built of 37 trillion cells and if you look in a text book, it will say there are about 200 distinct varieties of cells. But this is a grand underestimate. There could in fact be 10,000. The Human Cell Atlas project aims to identify every type and subtype of cell in every tissue of the body - a massive endeavour which, the cell mappers argue, will have profound benefits for medicine.Adam Rutherford also talks to zoological archaeologist Angela Perri whose research is aimed at discovering when our ancestors first started to use dogs as 'hunting' technology. Her work involves joining hunts with dogs in the modern day as well as traditional archaeological field work.He also explores the science behind exploding smart phone batteries and the new international climate agreement to rid the world of hydrofluorocarbons.

20 Okt 201630min

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