Neanderthals; Plague; Wind Tunnel; Music Timing; Stem Cells

Neanderthals; Plague; Wind Tunnel; Music Timing; Stem Cells

We now know that Neanderthals and our ancestors interbred over 40,000 years ago. Recent research has shown that most people of European or East Asian descent carry a small percentage of Neanderthal DNA - about 2%. But two new papers this week examine some of the physical characteristics we may have got from the genes of our ancient cousins. They include some disease susceptibilities and hair and skin characteristics, which may have helped our forebears survive in northern climes.

There have been many sensationalist headlines in the news this week suggesting that the deadly bubonic plague could return, when really, it never went away. And while it can still be deadly, it can be treated early with antibiotics. In the Middle Ages the Black Death is thought to have killed up to half of the European population and so too did the Justinian Plague 800 years earlier. Now scientists have compared these two plague genomes to find that they were both caused by distinct strains of the same bacterium, Yersinia Pestis. Knowing how the pathogen evolved in the past is crucial to our understanding of possible future strains of plague. Lead author Dr David Wagner from the University of Arizona tells Dr Adam Rutherford that it's very unlikely the plague will return on a mass scale.

It's a windy Show Us Your Instrument this week - Prof Konstantinos ('Kostas') Kontis, Professor of Aerospace Engineering shows us around his wind tunnel. It's used to help develop more effective plane wings, helicopter rotors, and wind turbine blades, but cyclist Sir Chris Hoy has also been a test sample. Glasgow University is currently building a hypersonic wind tunnel, which can test air flow at speeds of up to Mach 10.

We all unconsciously synchronise our movements and researchers at the University of Birmingham have shown how professional musicians make tiny adjustments in their playing to keep time with their colleagues. Alan Wing, Professor of Human Movement in Psychology tells Adam how this research about minute synchronisation is helping to inform how robots can be designed to interact with humans.

Stem cells can become any other cell in the body from nerve to bone to skin, and they are touted as the future of medicine. Embryos are one, often ethically charged, source of stem cells and in 2006 Nobel prize winning research showed that skin cells could be "genetically reprogrammed" to become stem cells. These were called induced pluripotent stem cells. Scientists in Japan have now shown, in mice, that this previous painstaking method of making the versatile cells can be replaced by little more than a short dip in acid. Professor Chris Mason from University College London tells Adam that this major breakthrough could be faster, cheaper and possibly safer than other cell reprogramming technologies.

Producer: Fiona Hill.

Avsnitt(614)

Lab-grown leather; Goal line technology; Bacteria outrage; Marine buoy

Lab-grown leather; Goal line technology; Bacteria outrage; Marine buoy

Cultured meat was on the menu earlier this week, but Mark Post's public tasting of his lab-grown burger marks the culmination of decades of research on producing artificial meat. Adam Rutherford talks to one of the other major players in the world of manmade animal products, Gabor Forgacs. However, his company, Modern Meadow, is concentrating on launching a different product first - cultured leather.The football season is about to start, and for the first time electronic Goal Line Technology will be introduced. This year will see the Hawk-Eye system deployed at all Premier League grounds in an attempt to help referees make more informed decisions. But how will it work, and how accurate can it be? Inside Science speaks with the inventor, Paul Hawkins, and the engineers who are testing it to international standards.A bacteria or a bacterium? We sparked a controversy on last week's programme by using bacteria to describe a singular microbe. Adam talks to evolutionary biologist Mark Pagel about how words evolve and whether scientists can halt their adaptation.This week on 'Show Us Your Instrument', oceanographer Helen Czerski introduces her giant marine buoy. She'll be sailing into the eye of a storm just off the south coast of Greenland later this year, where the buoy will measure bubbles to help refine climate models.

8 Aug 201327min

Crash risk; Mary Rose bacteria; History of Science; Greenwich telescope

Crash risk; Mary Rose bacteria; History of Science; Greenwich telescope

July has seen train crashes in Canada, Pakistan, France, Spain and Switzerland. Inside Science asks if this is a trend or just a coincidence. Professor David Spiegelhalter, an expert in the public perception of risk, explains whether there is such a thing as a 'crash season'. Microbiologists working on the Mary Rose in Portsmouth have discovered a new type of metal-eating bacteria which is damaging the ship's wooden timbers. Reporter Gaia Vince goes behind the scenes at Portsmouth's Historic Dockyards to find out how conservation scientists have saved the ship. Last week Manchester hosted the 2013 International Congress of History of Science Technology and Medicine, the biggest ever meeting of historians of science from around the world. The keynote speech was given by Prof Hasok Chang of the University of Cambridge, urging his colleagues to put "Science back in History of Science". Inside Science asked him if there should also be more history in the practice of science... Finally, Dr Marek Kukula Public Astronomer at the Greenwich Observatory shows us his instrument - the 28inch refracting telescope which historians at the time likened to a Spanish onion, or the Taj Mahal.

1 Aug 201327min

2D supermaterials; Inside an MRI; Antarctic architecture

2D supermaterials; Inside an MRI; Antarctic architecture

Nobel Prize and - as of this week, Copley Medal - winner Andre Geim outlined in Nature today his vision for the next generation of super-materials. Chemist Prof Andrea Sella joins Adam to explain how the discovery of graphene may have been the start of a remarkable new class of tailor made materials technically known as 'Van der Waals heterostructures'.This week on Show Us Your Instrument, Prof Sophie Scott introduces the MRI machine and explains why you never press the 'quench' button, unless you want to blow the roof off.Finally, an exhibition on Antarctic architecture opens on Friday 26th July in Glasgow, commissioned by the British Council and curated by The Arts Catalyst. We talk to Hugh Broughton who designed the new Halley VI base, a Thunderbirds inspired building, perched on top of stilts, on top of skis.Plus, Adam calls the current Halley Base Commander, Agnieszka Fryckowska, to find out what it's like to live and work during three months of darkness.Producer: Michelle Martin.

25 Juli 201327min

Animal research; Astronaut selection; Show us your instrument

Animal research; Astronaut selection; Show us your instrument

This week saw the publication of the annual government statistics on scientific research on animals. Overall, it again shows an increase, but does that tell the whole story? Wendy Jarrett of the organisation Understanding Animal Research shares her thoughts.We hear from amateur and professional would-be astronauts about their training regime and selection process from Major Tim Peake, the UK’s next astronaut, to science broadcaster, Sue Nelson.Plus, the first in our new series ‘Show Us Your Instrument’. Material scientist Mark Miodownik introduces the wonders of the Transmission Electron Microscope, with music composed by the New Radiophonic Workshop.

18 Juli 201329min

Bioscience to bioweapons; Synthetic diamonds; Stem cell transplants

Bioscience to bioweapons; Synthetic diamonds; Stem cell transplants

Scientists investigate viruses in order to save lives. But could that same knowledge also help other people create dangerous viruses to use as weapons of terror?This Thursday evening, a public debate is being held by the Society of Biology around these issues of "Dual Use" research. In an age of synthetic biology, mail order genes, and open access publication, what are the pros and cons of sharing virology research?Also this week, a new centre for research into synthetic diamonds was opened by UK Science Minister David Willetts. Inside Science reporter Marnie Chesterton took a tour of the new facility to find out how diamonds might be a quantum computer's best friend.Plus, the first formal trial of a stem cell based organ transplant is happening in the UK. Martin Birchall from University College London is working on replacing the larynx. But if a patient receives a new voicebox from a donor, whose voice will they have?

11 Juli 201328min

Bovine TB; Coral sunscreen; Space junk

Bovine TB; Coral sunscreen; Space junk

Today the government announced a plan to rid England of bovine TB within 25 years. Adam Rutherford looks back at how this issue has evolved and the extent to which scientific evidence has informed the eradication strategies, from culling badgers to vaccination programs.Pharmacognosy is the study of medicines found in nature. Reporter Gaia Vince travels to the seaside to find out how corals could save us from sunburn in summers to come.There are an estimated 23,000 pieces of space junk around the size of a tennis ball floating above us. But there are millions of smaller bits of flotsam and jetsam, from the exploded rocket debris to fleck of paints. Even a 1cm bit of space debris could deliver the same energy as a car impacting on a concrete wall at 30 miles per hour.

4 Juli 201327min

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