ExpeRimental; Rosetta; MOOCs

In a major advance in the field of embryology, scientists this week have kept human embryos alive in petri dishes for record amounts of time. The legal limit for keeping fertilised human embryos in the lab is 14 days, a cut-off point set in 1979. Back then, scientists were able to keep embryos alive for only a few days, meaning the limit was only a theoretical one. Advances mean that this week, in 2 papers, researchers have reached that limit. Professor Ali Brivanlou, Robert and Harriet Heilbrunn Professor of Stem Cell biology and molecular embryology at Rockefeller University is lead author on one of the papers, and Professor Bobbie Farsides is a clinical and biomedical ethicist at Brighton and Sussex Medical School. They join Adam to discuss the next steps for embryology. Should this limit curtail research?Next Monday is the transit of Mercury. 13 times a century, Mercury passes directly between us and the Sun, and creates a pinprick shadow, a pixel of black for about 8 hours. This strange planet has no atmosphere, but a lot explosive volcanic activity. It has an eccentric orbit - meaning its distance from the sun fluctuates wildly. A Mercury year is 88 Earth days, but a Mercury day lasts almost two mercury years. David Rothery is a professor of Planetary Sciences at the Open University. He reveals how scientists study this planet and explains how, and how not to view the transit of Mercury.Overfishing is one of the biggest threats to the health of our oceans. According to the UN, up to a third of the world's fisheries are overexploited or depleted. It is a huge complex problem with many inputs and outputs to compute. So who better to tackle it than a team of hackers? Recently, coders around the globe gathered to take on the challenge, in a 48-hour Fishackathon. Reporter Anand Jagatia went along and reports back to AdamMost dog lovers will know that Labradors are particularly keen to eat anything, all the time, at any time. As a result, some are a bit corpulent, even obese. The cause is likely to be in their genes. A new study in the current issue of Cell Metabolism has identified that genetic basis for the perpetual hunger. Eleanor Raffan from Cambridge University, geneticist and vet, led the study. She explains to Adam how she gathered a cohort of dogs.

5 Maj 201628min

30 years ago this week an explosion at the Chernobyl nuclear plant. A fire raged for 10 days, spewing radioactive materials on the surrounding area and was detected throughout much of a continent. Yet, so many decades on, why is it so difficult to accurately measure the impacts on human health? Richard Wakeford of the University of Manchester is an epidemiologist who has looked at the research done over the years, and he explains why making definitive connections between the Chernobyl explosion and long-term illnesses or premature deaths is so very difficult.In the last few days there have been reports that a drone hit a plane on its way into Heathrow. Investigators say there is so little evidence either way it is not possible to say whether it really was a drone, but either way, the story has raised concerns. BBC Inside science spoke to Dr Sue Wolfe of ARPAS, to find out how our increasingly crowded air space is regulated. And Adam goes drone flying with BBC innovations producer, Derrik Evans, to see how easy these things are to use.If the hum of drones is annoying, imagine the constant din of the rain forest, especially tricky if you're a cricket and you're trying to find a mate. We have a listen to the strategies they use to be heard above the cacophony in the company of Dr Tim Cockerill. Scientists at CERN have also been trying to sort out the wheat from the chaff, continuing their efforts to understand a blip in their data identified and scrutinised over the last few months. Jon Butterworth of UCL and CERN dons the Cloak of Speculation and talks about the possible implications for physics if it does indeed turn out to be a new, unpredicted, particle.

28 Apr 201632min

The UK science community draws vital benefits from EU membership and could lose influence in the event of an exit, says a House of Lords report out this week. UK researchers placed a high value on collaboration opportunities afforded by EU membership. A number also believe the UK would lose its ability to influence EU science policy in the event of leaving - something that's disputed by pro-Brexit campaigners. To debate the ins and outs of being in or out of the EU, Adam is joined by Viscount Matt Ridley, a member of the committee, and Professor Paul Boyle, the Vice Chancellor of Leicester University and former president of Science Europe.Scientists at Aarhus University in Denmark are developing a quantum computer. To help them solve a particular problem, they have turned to human brain power, harnessing our ability to play computer games. The team have designed video games, such as Quantum Moves - that are helping them to understand the problem of 'slosh'- that atoms move about, when moved, like water sloshing in a cup.Many diseases are caused by a particular type of DNA error called a 'point mutation'. In our genomes, the substitution of a single letter of genetic code can be the root cause of diseases such as Alzheimer's, sickle cell anaemia, and a whole range of cancers. Recently, a new technique for editing DNA, called CRISPR, a precise genetic engineering tool, was developed, which might help combat these diseases. The problem is that the cell often reacts to this editing; trying to mend what it perceives as damage to its DNA. This week, David Liu, from Harvard University, published new research showing how his team have managed to switch out a single letter, a base pair, whilst tricking the cell into not correcting this edit.

21 Apr 201627min

This week Russian internet billionaire Yuri Milner announced a project to send tiny spaceships to Alpha Centauri. Milner, alongside Stephen Hawking, announced a $100 million project to develop and launch a cloud of spaceships with sails. They'll be powered by giant lasers based on earth, and will fly at one fifth the speed of light. The Breakthrough Starshot project sounds like science fiction - Adam is joined by Professor Andrew Coates from UCL's Mullard Space Science Laboratory to sort the feasible from the fantasy.Space travel is expensive. Scientists and engineers met recently to discuss a way of making it cheaper. Sending men back to the moon to mine it may sound like a hugely costly process, but as reporter Roland Pease discovers, when it comes to future space missions, it might become an essential part of the process.Closer to home than the moon is a section of the atmosphere called the thermosphere that is poorly understood. A European project called QB50 plans to change this, by sending 50 small satellites, known as CubeSats, into orbit this summer. Most of them will sport sensors that can probe the properties of the upper atmosphere. The group building these sensors is led by UCL's Mullard Space Science Laboratory, which will build 14 spectrometers. These will analyse the relative proportions of different types of particles in the thermosphere. Marnie Chesterton finds out how scientists cope with the challenge of building their gadgets smaller and lighter.Many listeners wrote in after a recent piece on solar panels. We had queries about how to store the electricity, and whether PV panels are worth the energetic cost of producing them and what units to use. We put all these questions to Jenny Nelson, Professor of Physics at Imperial College and author of 'The Physics of Solar Cells.'.

14 Apr 201628min

This week a "Faraday Discussion" - a unique way of presenting and sharing cutting edge science - is underway at the Royal Society of Chemistry in London looking specifically at Chemistry in the Urban Atmosphere. As Prof Ally Lewis of York University tells Adam Rutherford, atmospheric chemistry is so complex, and detector standards so variable - in particular the cheaper commercial brands - that it can be hard to check whether our environmental policies are working. Whilst local and national governments spend precious public money checking for compliance with a number of common pollutants, atmospheric chemists would like a more investigative approach, looking at the chemistry in action, rather than the end products.Do you suffer in the spring and summer? Allergies are on the increase in the UK. And scientists don't know why. But the environment, and what we breathe from it, is thought to be key. A new app for smartphones called Britain Breathing has been developed by scientists at Manchester University working with allergy sufferers. Hay fever affects millions of Britons but is under-reported and poorly understood. Combining large numbers of reports of symptoms with their location and time could lead to valuable insights.Last December, BBC Inside Science reported on the mothballing of several Carbon Capture and Storage pilot schemes, following withdrawal of government funding. But some work continues. Doug Connelly of the National Oceanographic Centre in Southampton tells Adam about a scheme currently trialling carbon storage in the North Sea, to see whether disused oil and gas fields can be used to store our dangerous emissions.A little over 2200 years ago, Carthaginian general Hannibal Barca infamously led a huge army of elephants and horses across the Alps, almost to the gates of Rome. It has been celebrated as one of the most audacious military campaigns in history, but his exact route has always been subject to debate. This week further results from a consortium of disparate scientists have been published, supporting their preferred route taken by the grand army. Microbiologist Chris Allen from Queen's University talks Adam Rutherford through the "deposition of data", marking the passage of thousands of animals. What is the new evidence? A microbially recalcitrant, precisely dated, phylogenetically relevant layer of euphemism.

7 Apr 201627min

The world's second largest floating solar farm has just started generating power. Built on the Queen Elizabeth II reservoir in West London, it's the size of eight football pitches and can provides enough power for 1,800 homes. Its construction was a race against time, because the UK government cuts subsidies for new solar farms from April. Adam Rutherford talks to Leev Harder from Lightsource Renewable Energy about the project. Dr Iain Staffel is a sustainable energy expert at Imperial College London and he explains the main issue with solar: the difficulties in storing the electricity produced until it's needed.A team from Glasgow University has invented a portable gravity detector. Volcanologist Hazel Rymer from the Open University discusses how this cheap and portable device can detect tiny changes in gravity in the ground. She hopes to use this kind of device to monitor what's happening inside volcanoes soon.In New Zealand, the near-extinct kakapo will become the first species to have the genome of every single member sequenced, thanks to a crowd-funded conservation project. Adam Rutherford meets geneticist Peter Dearden, in the Zealandia conservation area in Wellington, to chat about these charming but daft birds, and efforts to save them from extinction.Producers: Marnie Chesterton and Jen Whyntie.

31 Mars 201631min

The flu season is running later this year. And it has been unusually virulent. Professor Wendy Barclay, virologist at Imperial College London, tells Tracey Logan about the constant race to keep up with flu mutations in order to build an effective vaccine.Wine has a microbial terroir which is thought to affect its taste. A new paper suggests coffee and chocolate might do too. Aimee Dudley from the Pacific Northwest Diabetes Research Institute in Seattle has studied global populations of yeast found on cacao and coffee beans. She explains that these yeast varieties are genetically diverse. Tracey Logan travels to coffee supplier Union, to meet scientist-turned-coffee-buyer, Steve Macatonia, and unpick the flavours of coffee.In Delft, the world's biggest artificial waves are pitted against a new kind of super-strong sea wall. The Delta Flume team, led by Mark Klein Breteler, has created a giant concrete channel with a wave generator. Reporter Roland Pease turns up in time to see the team testing their artificial waves against a 10 metre dyke.People with cochlear implants hear a degraded version of speech. Using subtitles helps train the brain to understand it faster. Matt Davis and Ed Sohoglu from the Medical Research Council's Cognition and Brain Science Unit in Cambridge suggest that this feeds into a model of how the brain learns called Perception Learning.

24 Mars 201627min

Research in Nature this week shows that lost memories in mice can be rescued by reactivating a group of memory cells in the brain called 'engram' cells. The team suggests that their research might prove useful for Alzheimer's patients in the future. Professor John Hardy, neuroscientist at University College London and Dr Prerana Shrestha from the Center for Neural Science at New York University discuss the work with Tracey.The migrating white stork is well-known in folklore as the bringer of babies. In recent years, large numbers of them have decided to stop flying to Africa for winter, and live all year round, feasting on food from landfills in Portugal. Dr Aldina Franco from the University of East Anglia has been studying these birds and talks to Tracey about these adapting birds.A scientist at Royal Holloway University in London has discovered the oldest-known fossil of a pine tree. Howard Falcon-Lang discovered the fossils in Nova Scotia, Canada, and brought some back to his office. 5 years later, he dissolved a sample of what looked like charcoal in acid and discovered charred pine twigs. These date back 140 million years to a time when fires raged across large tracts of land. Reporter Roland Pease visits his lab to look at the samples close up. The research suggests the tree's evolution was shaped in the fiery landscape of the Cretaceous, where oxygen levels were much higher than today, fuelling intense and frequent wildfires. UK Gardeners may have noticed summer flowers blooming at unusual times this winter. Tracey meets up with seed scientist Steve Penfield and crop geneticist Judith Irwin in a greenhouse at the John Innes Centre. They explain how seeds and flowering times are affected temperature changes.

17 Mars 201627min