Nobel Prizes 2014; Gauge; Genetics and Diabetes; UK Fungus Day

Nobel Prizes 2014; Gauge; Genetics and Diabetes; UK Fungus Day

Nobel Prizes 2014 The annual Nobel Prizes for Physiology or Medicine, Physics and Chemistry were announced this week.

The Nobel Prize for Physiology or Medicine has been awarded to UK-based researcher Prof John O'Keefe as well as May-Britt Moser and Edvard Moser who discovered the brain's "GPS system". They discovered how the brain knows where we are and is able to navigate from one place to another. Their findings may help to explain why Alzheimer's disease patients cannot recognise their surroundings.

The 2014 Nobel Prize for physics has been awarded to Professors Isamu Akasaki, Hiroshi Amano and Shuji Nakamura in Japan and the US, for the invention of blue light emitting diodes (LEDs). This enabled a new generation of bright, energy-efficient white lamps, as well as colour LED screens.

The 2014 Nobel Prize in Chemistry has been awarded to Eric Betzig, Stefan Hell and William Moerner for improving the resolution of optical microscopes. This type of microscope had previously been held back by the presumed limitation that obtaining a better resolution than half the wavelength of light would be impossible. But the laureates used fluorescence to extend the limits of the light microscope, allowing scientists to see things at much higher levels of resolution.

GAUGE The UK has a database for the amount of greenhouse gases we emit each year - usually measured in Gigatonnes of carbon. It's compiled by adding up emissions from various individual sources - be it a coal-fired power station or a wetland bog. This amount is used worldwide, but it is an estimate. A project called Greenhouse gas UK and Global Emissions, or GAUGE, is - for the first time - verifying these estimates by measuring what's in the atmosphere on a much larger scale.

Genetics and Diabetes Type 2 diabetes is globally the fastest growing chronic disease. The World Health Organisation estimates more than 300 million people are currently afflicted, rising to more than half a billion by 2030. It might seem on the surface to be a disease with a simple cause - eat too much & exercise too little - and the basic foundation is a relative lack of the hormone insulin. But as with most illnesses, it's much more complicated, not least because a large number of disease processes are happening all at once. In 2010, a particular gene variant was associated with around 40% of Type 2 diabetics - not directly causal, but this so-called 'risk variant' increases the chance of developing the condition if you have the wrong lifestyle. Research published in the journal Science Translational Medicine this week identifies a drug called yohimbine as a potential treatment to help Type 2 diabetics, one that targets this specific genetic make-up.

UK Fungus Day October 12th is UK Fungus Day, a chance for us to celebrate these cryptic, often microscopic, but essential organisms. Usually hidden away inside plants or in soil (or if you're unlucky, in between your toes), fungi have largely been growing below scientists' radars for centuries. Mycologists still don't know anything close to the true number of fungi that exist on the planet. About a hundred thousand have been formally identified, but it's estimated that anywhere from half a million to ten million species may exist. This dwarfs, by several orders of magnitude, how many mammals there are on Earth. And, increasingly, we're realising quite how crucial fungi are to the functioning of our ecosystems. Head of Mycology at The Royal Botanic Gardens Kew, Bryn Dentinger, explains how valuable fungi really are.

Producer: Fiona Roberts Assistant Producer: Jen Whyntie.

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Board Game Science

Board Game Science

It’s that time of the year when many of us are at home with friends and family, losing track of time, eating leftovers, and, of course, playing games. This festive season, we look at the science of games and, of course, play some ourselves. It’s presenter Marnie Chesterton versus producer Florian Bohr at Marnie's kitchen table.... Who will win the Inside Science games special?Irving Finkel from the British Museum tells Marnie about the Royal Game of Ur, one of the most ancient board games which is strikingly similar to more modern examples of race games. Also, why we play games with author and neuroscientist Kelly Clancy, and why we struggle to comprehend the randomness of dice with author Tim Clare. To finish it off, mathematician Marcus du Sautory explains the geometry behind the game Dobble and leaves listeners with a Christmas puzzle: Can you figure out the symbols on the two missing Dobble cards? If you think you’ve found the solution, please email insidescience@bbc.co.ukPresenter: Marnie Chesterton Producers: Florian Bohr Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth    To discover more fascinating science content, head to bbc.co.uk search for BBC Inside Science and follow the links to The Open University.

23 Jan 28min

The Year in Science

The Year in Science

We look back on 2024 in science, from billionaires in space, to record-breaking heat here on Earth, and the meteoric rise of new weight-loss drugs. From the biggest stories to the unsung and the plain fun, Inside Science presenter Victoria Gill hosts a special panel, featuring: - Libby Jackson, head of space exploration at the UK Space Agency - Penny Sarchet, managing editor of New Scientist - Mark Miodownik, a materials scientist from University College London Presenter: Victoria Gill Producers: Gerry Holt Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth  To discover more fascinating science content, head to bbc.co.uk search for BBC Inside Science and follow the links to The Open University.

16 Jan 28min

The rising threat of bird flu

The rising threat of bird flu

More species infected than ever, an uptick in human cases, and some concerning biological modifications. How close are we to a bird flu pandemic? We digest the last year of bird flu changes with virologist Tom Peacock and public health journalist Melody Schreiber. Also this week, we address the absurd problem of transporting something that can't be touched, we find out how animals make their epic migratory journeys, and Victoria Gill visits a town which has learnt to ward off a fearsome predator, polar bears.Presenter: Victoria Gill Producers: Ella Hubber & Gerry Holt Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth  & Josie HardyTo discover more fascinating science content, head to bbc.co.uk search for BBC Inside Science and follow the links to The Open University.

9 Jan 28min

Fact-checking the Bovaer backlash

Fact-checking the Bovaer backlash

Some social media users have been pouring milk down the drain and chucking their butter in the bin in protest over a new additive in cow feed that claims to reduce methane emissions. The online posts, attacking Arla Food’s trial of Bovaer with three big supermarkets and 30 farms in the UK, have had millions of views. So, what do we know – what is this additive and how is it going to tackle burpy cows? And what is the evidence it is safe? We interrogate the science with Sharon Huws, professor in animal science, and food scientist Dr Stuart Farrimond... Also this week, are billionaires really deserting Earth for space? What is the upshot for our plastic waste problem after global talks on a treaty ended in failure? And why, just why, are orcas being spotted wearing salmon hats? Presenter: Victoria Gill Producers: Sophie Ormiston, Ella Hubber & Gerry Holt Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth  To discover more fascinating science content, head to bbc.co.uk search for BBC Inside Science and follow the links to The Open University.

2 Jan 28min

Is flood forecasting failing?

Is flood forecasting failing?

The south Wales town of Pontypridd saw cars submerged, people bailing floodwater out of their homes using bins, and the beautiful park and lido transformed into a brown mess, as parts of the UK were flooded. But, it's nothing new. Pontypridd was severely flooded just four and a half years ago – and these are scenes that play out around the UK every winter. So, is the way we warn people about floods failing? We’re going to unpick exactly how floods are forecast – and what went wrong – with natural hazards researcher and hydrologist, Professor Hannah Cloke. Also this week, sharing your microbiome with friends, alternative plastics, and was the most recent climate summit good COP or bad COP? Presenter: Victoria Gill Producers: Gerry Holt, Sophie Ormiston & Ella Hubber Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth  To discover more fascinating science content, head to bbc.co.uk search for BBC Inside Science and follow the links to The Open University.

26 Dec 202428min

The climate cost of war

The climate cost of war

As conflicts in the Middle East and Ukraine continue to dominate the news, many Inside Science listeners have been in touch with the same question: What is the carbon footprint of war? How significant is the impact – and is it crass to even talk about it? We’re joined by Benjamin Neimark from Queen Mary University in London. Also this week, we chat to the incoming DG of Europe’s particle-smashing facility Cern, what have we learnt by defrosting an extinct big cat and, the beetle that could ruin Christmas... Presenter: Marnie Chesterton Producers: Florian Bohr, Ella Hubber & Gerry Holt Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth  If you want to test your climate change knowledge, head to bbc.co.uk search for BBC Inside Science and follow the links to The Open University to take the quiz.

19 Dec 202427min

Nuclear medicine shortages and Jane Goodall on COP29

Nuclear medicine shortages and Jane Goodall on COP29

A shortage of medical isotopes used to detect cancer has experts concerned that the shortfall could be delaying diagnosis and could even be costing lives. Exactly what these nuclear medicines are and how they are made is key to understanding the national scarcity. So, we’re going back to basics and learning all about medical isotopes. We also speak to world-famous conservationist and primatologist Jane Goodall who, now aged 90, continues to travel the globe campaigning to protect the natural world. Dame Goodall reflects on a life of studying our closest living animal relatives, chimpanzees, and as COP29 gets under way, speaks about the “closing window of time” to turn the tide on climate change and nature loss. Also this week, we answer the listener question “Why don’t we just throw nuclear waste into volcanoes?” and can Marnie spot AI vs real poetry? Presenter: Marnie Chesterton Producers: Ella Hubber & Gerry Holt Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth  To discover more fascinating science content, head to bbc.co.uk search for BBC Inside Science and follow the links to The Open University.

12 Dec 202428min

COP29: Are climate summits working?

COP29: Are climate summits working?

This year is set to be the world’s hottest on record, likely shattering the aspiration to limit global warming to 1.5C above pre-industrial levels. So where does this leave COP29, the upcoming UN climate conference in Azerbaijan? This week Inside Science is asking, are climate summits really working? What is the point of them - and are they doing enough? Joining Marnie Chesterton to discuss this are: - Joanna Depledge, expert on international climate negotiations at the University of Cambridge - Mark Maslin, climate change professor from University College London (UCL) - Jim Watson, professor of energy policy, also from UCL Presenter: Marnie Chesterton Producers: Ella Hubber, Sophie Ormiston & Gerry Holt Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth If you want to test your climate change knowledge, follow the links on this page to The Open University to take a quiz.

5 Dec 202428min

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