How To Reap The Anti-Inflammatory and Longevity Benefits Of Astaxanthin with David M. Watumull
The Dr. Hyman Show19 Juli 2023

How To Reap The Anti-Inflammatory and Longevity Benefits Of Astaxanthin with David M. Watumull

This episode is brought to you by Rupa Health, Mitopure, Sunlighten, and Thrive Market. As we age, our body’s natural antioxidant defenses slow down, driving chronic inflammation and diminishing overall health. To combat inflammaging, scientists have been studying compounds that can reduce inflammation and oxidative stress in the body. One such compound is astaxanthin, a powerful, naturally occurring antioxidant with profound anti-inflammatory health benefits. Today on The Doctor’s Farmacy, I’m excited to talk to David M. Watumull all about astaxanthin and how it helps to combat some of the key hallmarks of aging—inflammaging, mitochondrial dysfunction, and cell signaling. David M. Watumull has more than twenty years of experience in product development, commercialization, and business management related to astaxanthin—a safe and powerful, naturally-occurring anti-inflammatory—for human health. He is the co-founder and CEO of AX3 Life, a consumer longevity company formed to help people be their best selves longer. AX3 Life targets inflammaging—a core hallmark of aging—at its source with AX3 bio-pure astaxanthin. He is also the COO of Cardax, a life sciences business focused on advancing pharmaceutical and nutraceutical applications of astaxanthin. This episode is brought to you by Rupa Health, Mitopure, Sunlighten, and Thrive Market. Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Mitopure is the first and only clinically tested pure form of a natural gut metabolite called urolithin A that clears damaged mitochondria away from our cells and supports the growth of new healthy mitochondria. Get 10% off at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. When it comes to infrared saunas, my number one brand is Sunlighten. Right now, you can save up to $600 on your purchase. Simply visit Sunlighten.com/mark-hyman and mention my name, Dr. Hyman, to save. Thrive Market is offering 30% off your first order and a free gift worth up to $60 if you sign up now at thrivemarket.com/Hyman. Here are more details from our interview (audio version / Apple Subscriber version): Steps to reduce and manage oxidative stress and inflammation (4:18 / 2:25) How astaxanthin targets key hallmarks of aging (7:02 / 4:35) Life span benefits of astaxanthin (13:34 / 11:32) How astaxanthin benefits joint, muscle, and cardiovascular health and cognitive function (15:09 / 13:26) Where astaxanthin is found in nature (22:38 / 18:47) The FOXO3 gene (27:54 / 24:05) Astaxanthin for longevity and healthy aging (37:23 / 34:45) Synthetic vs natural astaxanthin (39:54 / 36:03) Learn more about the astaxanthin supplement AX3.

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How to Love Better: Emotional Healing, Attachment, and Real Relationship Skills with Yung Pueblo

How to Love Better: Emotional Healing, Attachment, and Real Relationship Skills with Yung Pueblo

We all know emotional maturity is essential for a healthy relationship—but how do you actually get there? In this episode of The Dr. Hyman Show, I talk with Diego Perez, the #1 New York Times bestselling author known as Yung Pueblo, about the small mindset shifts that can make a huge difference in how you show up for yourself and your partner. Drawing from his new book, How to Love Better, Diego shares how to stop repeating the same old patterns and start building relationships grounded in awareness, honesty, and real emotional growth. In this conversation, we explore: Why emotional maturity is the #1 skill for resolving conflict How letting go of control can lead to more trust, connection, and ease in your relationship How your old emotional patterns might be causing tension you don’t even realize Why owning your emotions can help you avoid blame and grow together Simple mindset shifts that can make love feel more secure, stable, and honest Check out the episode for a practical, compassionate guide to loving better. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast This episode is brought to you by Sunlighten, Timeline Nutrition, Paleovalley, and LMNT.  Visit sunlighten.com and save up to $1400 on your purchase with code HYMAN. Support essential mitochondrial health and save 10% on Mitopure. Visit timeline.com/drhyman to get 10% off today. Get nutrient-dense, whole foods. Head to paleovalley.com/hyman for 15% off your first purchase. Get a free LMNT Sample Pack with any order—just head to drinklmnt.com/hyman.

23 Apr 1h 10min

Mold, Lyme, Gut Health, and the Mystery of Histamine Intolerance

Mold, Lyme, Gut Health, and the Mystery of Histamine Intolerance

Many people struggle with mysterious symptoms like fatigue, brain fog, food sensitivities, and skin issues—only to be misdiagnosed or dismissed altogether. This conversation highlights how histamine intolerance and mast cell activation syndrome can be the hidden drivers behind a wide range of chronic conditions, and why they're often overlooked in conventional medicine. From the role of gut health, food triggers, and environmental toxins to deeper root causes like Lyme disease or mold exposure, it’s clear that personalized, Functional Medicine is key to uncovering real answers. Understanding the immune system’s role in histamine reactions—and how even “healthy” foods can be inflammatory for some—is a critical step toward healing. In this episode, I talk with Dr. Todd LePine, Dr. Elizabeth Boham, and Dr. Mark Pimentel about what histamine intolerance is, how it can be related to gut health, and why it’s important to address it. Dr. Todd LePine graduated from Dartmouth Medical School and is Board Certified in Internal Medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine Certified Practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine’s focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders. Dr. LePine enjoys skiing, kayaking, hiking, camping, and golfing in the beautiful Berkshires, and is a fitness enthusiast. Dr. Elizabeth Boham is Board Certified in Family Medicine from Albany Medical School, and she is an Institute for Functional Medicine Certified Practitioner and the Medical Director of The UltraWellness Center. Dr. Boham lectures on a variety of topics, including Women’s Health and Breast Cancer Prevention, insulin resistance, heart health, weight control and allergies. She is on the faculty for the Institute for Functional Medicine. Dr. Mark Pimentel is a Professor of Medicine and Gastroenterology through the Geffen School of Medicine and an Associate Professor of Medicine at Cedars-Sinai. Dr. Pimentel is also the Executive Director of the Medically Associated Science and Technology (MAST) program at Cedars-Sinai, an enterprise of physicians and researchers dedicated to the study of the gut microbiome in order to develop effective diagnostic tools and therapies to improve patient care.  Dr. Pimentel has over 150 publications in many high-profile journals, and he is the author of the book, The Microbiome Connection: Your Guide to IBS, SIBO, and low fermentation eating. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: Is Histamine Intolerance The Cause Of Your Mysterious Symptoms? What is Histamine Intolerance? Surprising Symptoms You Need to Know IBS: It’s Not In Your Head—Advances In Diagnosing And Treating, Bloating And Tummy Troubles

21 Apr 1h 1min

Ultra-Processed People: How Big Food Is Rewiring Our Brains | Chris Van Tulleken

Ultra-Processed People: How Big Food Is Rewiring Our Brains | Chris Van Tulleken

Ultra-processed food is the new cigarette—and it's fueling a global health crisis hiding in plain sight. In today’s episode, I’m joined by Dr. Chris van Tulleken—infectious disease physician, BBC broadcaster, and author of Ultra-Processed People—to expose the truth behind ultra-processed foods and the industries driving their consumption. To find out what this food is really doing to us, Dr. van Tulleken became the first subject in a groundbreaking clinical trial—eating 80% of his calories from ultra-processed food for a full month. We unpack what makes ultra-processed food fundamentally different from real food—even when the ingredients look similar, and why its impact on your brain, metabolism, and long-term health is far worse than anyone thought… You’ll learn: How ultra-processed food hijacks your brain’s reward system The science behind food addiction and satiety hormones Why food labels and front-of-package claims are designed to mislead you What the latest data says about UPFs and 32 chronic diseases The global policy movements and lawsuits now underway to fight back This episode is part science, part exposé, and a wake-up call for anyone who thinks food is just about calories and willpower. If you care about your health, your kids, or the future of our food system, you need to hear this. This episode is brought to you by Seed, Fatty15, PerfectAmino, BON CHARGE, and Pique. Visit seed.com/hyman and use code 25HYMAN for 25% off your first month of Seed's DS-01® Daily Synbiotic. Head to fatty15.com/hyman and use code HYMAN for 15% off your 90-day subscription Starter Kit. Get pure essential amino acids today. Go to bodyhealth.com and use HYMAN20 to get 20% off your first order. Go to boncharge.com and use code DRMARK to save 15% on your PEMF mat today. Head to piquelife.com/hyman to get 20% off + a free beaker and frother today. https://linktr.ee/ultraprocessedpeople View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast

16 Apr 1h 22min

The #1 Anti-Aging Tool You’re Ignoring (Hint: It’s Free and Happens at Night)

The #1 Anti-Aging Tool You’re Ignoring (Hint: It’s Free and Happens at Night)

Sleep is not just a luxury—it’s a foundational pillar of health that influences nearly every aspect of our well-being. Sleep deprivation doesn’t just cause fatigue; it disrupts hormones, drives inflammation, damages metabolism, and accelerates aging. From the gut microbiome to stress hormones like cortisol, sleep is deeply intertwined with brain, immune, and metabolic health. Yet our modern world—filled with late-night screens, ultra-processed foods, and chronic stress—works against quality rest.  In this episode, I discuss, along with Dr. Matt Walker and Shawn Stevenson, why we need to address sleep as a core health priority to unlock healing, prevention of chronic disease, and renewed vitality. Matthew Walker earned his PhD in neuroscience from the Medical Research Council in the UK, and subsequently became a Professor of Psychiatry at Harvard Medical School. He is currently a Professor of Neuroscience and Psychology at the University of California, Berkeley, and director of the Center for Human Sleep Science. Matt’s research focuses on the effect of sleep on human health and disease, brain, and body. He has published more than 100 scientific research studies and has received numerous funding awards from the National Science Foundation and the National Institutes of Health. Matt has given a main-stage TED Talk that has been viewed over 13 million times, has also created several TED Miniseries on sleep, a MasterClass series on sleep, and is author of the New York Times bestseller, Why We Sleep. Matt is also the host of the 5-star-rated, The Matt Walker Podcast. Shawn Stevenson is the author of the USA Today National bestseller Eat Smarter, and the international bestselling book Sleep Smarter. He’s also the creator of The Model Health Show, featured as the number #1 health podcast in the U.S. with millions of listener downloads each month. A graduate of the University of Missouri–St. Louis, Shawn studied business, biology, and nutritional science and became the cofounder of Advanced Integrative Health Alliance. Shawn has been featured in Forbes, Fast Company, The New York Times, Muscle & Fitness, ABC News, ESPN, and many other major media outlets. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: How to Optimize Your Sleep with Dr. Matthew Walker How To Stay Asleep And Sleep More Deeply Hack Your Sleep

14 Apr 59min

Food dye, ADHD, and Corporate Lies: How Big Food Targets Your Kids | Vani Hari

Food dye, ADHD, and Corporate Lies: How Big Food Targets Your Kids | Vani Hari

Are U.S. food companies cutting corners at the expense of your health? Vani Hari, known to many as the Food Babe, thinks so—and she’s spent over a decade sounding the alarm. In this episode of The Dr. Hyman Show, she shares why she believes many American products are still made with harmful additives and dyes, even though companies have found ways to remove them in versions sold abroad. In our conversation, she explains: Why she believes Kellogg’s and other U.S. brands aren’t doing enough to protect American consumers. The FDA loophole she says allows companies to self-approve food chemicals without oversight. How food dyes could be contributing to rising rates of behavioral issues in kids. The labeling gaps and industry tactics she says are keeping consumers in the dark. How everyday people can push back—and why she believes activism still works. Don’t miss this insightful episode! View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast This episode is brought to you by Sunlighten, Timeline Nutrition, Big Bold Health, and PaleoValley. Visit sunlighten.com and save up to $1400 on your purchase with code HYMAN. Support essential mitochondrial health and save 10% on Mitopure. Visit timeline.com/drhyman to get 10% off today. Try HTB Immune Energy Chews: visit bigboldhealth.com and use code DRMARK25 at checkout to get 25% off your purchase today. Get nutrient-dense, whole foods. Head to paleovalley.com/hyman for 15% off your first purchase. Head to piquelife.com/hyman to get 20% off + a free beaker and frother today.

9 Apr 1h 17min

Fatty Liver Is the New Smoking—And 90 Million Americans Have It

Fatty Liver Is the New Smoking—And 90 Million Americans Have It

What if your fatigue, weight gain, hormone imbalances, and brain fog all traced back to a silent disease that affects 1 in 3 people—and you didn’t even know you had it? In today’s episode, I’m joined by Dr. Elizabeth Boham and Dr. Yousef Elyaman to talk about a condition that’s quietly becoming one of the biggest threats to our health: fatty liver disease—now renamed Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). It’s not just a liver issue. It’s deeply connected to heart disease, cancer, infertility, type 2 diabetes, dementia, and even hormone dysfunction. The most alarming part is it’s often missed in traditional medicine because there’s no easy drug to prescribe. We break down: The real root causes—from sugar and starch overload to gut imbalances, toxins, alcohol, and chronic inflammation The surprising early warning signs your body might be giving you Why standard labs often miss it, and the tests you actually need The step-by-step functional medicine approach to reverse fatty liver naturally—using targeted nutrition, lifestyle upgrades, and proven supplements I also share the latest science on inflammation, why it’s the common thread between fatty liver and nearly every chronic disease, and how to calm it down at the root. This is the episode I wish every patient (and doctor) could hear—because fatty liver is reversible when you catch it early, and the ripple effects of healing it are massive. If you care about your energy, hormones, brain health, or longevity… this one’s for you. Dr. Elizabeth Boham is Board Certified in Family Medicine from Albany Medical School, and she is an Institute for Functional Medicine Certified Practitioner and the Medical Director of The UltraWellness Center. Dr. Boham lectures on a variety of topics, including Women’s Health and Breast Cancer Prevention, insulin resistance, heart health, weight control and allergies. She is on the faculty for the Institute for Functional Medicine. Dr. Yousef Elyaman is the founder and Medical Director of Absolute Health, a primary care functional medicine practice in Ocala, Florida. He is the 100th President of the Marion County Medical Society and the Functional Medicine Director at The Guest House Ocala, a trauma and substance abuse center. Dr. Elyaman also serves as the Medical Director for HumanN, a leading nutraceutical company, and is a Consultant for Quest Diagnostics Laboratory in their Wellness Division. He is teaching Faculty for the Institute for Functional Medicine on their Cardiometabolic module. Dr. Elyaman belongs to the first graduating class of the Institute for Functional Medicine. He is Board-certified in Internal Medicine and holds certifications in functional and integrative medicine as well. His leadership and expertise are reflected in his diverse roles, demonstrating his commitment to advancing medical knowledge and improving patient care. When not at work, Dr. Elyaman loves spending time with his wife and seven children where they live on a cattle and horse ranch. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: How To Prevent And Reverse Fatty Liver Disease with Functional Medicine The Best Diet to Reverse Fatty Liver Disease with Dr. Yousef Elyaman Why Fatty Liver Is So Common And How To Heal It

7 Apr 49min

Are You Nutrient Deficient? The Hidden Factors of Accelerated Aging | Rhonda Patrick

Are You Nutrient Deficient? The Hidden Factors of Accelerated Aging | Rhonda Patrick

We’re overfed, but undernourished. Despite having access to more food than ever, most people are walking around with nutrient deficiencies that could be accelerating aging, increasing disease risk, and depleting energy levels. That’s why I sat down with Dr. Rhonda Patrick, a leading expert in nutritional science and aging, to break down what we’re missing—and why it matters. In this episode of The Dr. Hyman Show, we explore: Why nearly 70% of Americans are deficient in vitamin D and what that means for longevity. The overlooked role of magnesium in metabolism, blood sugar, and brain function. Why our food system leaves us malnourished—even if we eat a “healthy” diet. The best way to assess and correct micronutrient imbalances for optimal health. Your body can’t function properly without the right nutrients. This episode will show you how to fill the gaps and take control of your health. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal This episode is brought to you by Seed, BON CHARGE, Pique, Perfect Amino, and AirDoctor. Visit seed.com/hyman and use code 25HYMAN for 25% off your first month of Seed's DS-01® Daily Synbiotic. Go to boncharge.com and use code DRMARK to save 15% on your PEMF mat today. Head to piquelife.com/hyman to get 20% off + a free beaker and frother today. Get pure essential amino acids today. Go to bodyhealth.com and use HYMAN20 to get 20% off your first order. Get cleaner air. Right now, you can get up to $300 off at airdoctorpro.com/drhyman.

2 Apr 1h 28min

From Inflammation to Conception: Solving the Fertility Puzzle

From Inflammation to Conception: Solving the Fertility Puzzle

Fertility challenges are increasingly linked to lifestyle and environmental factors that go far beyond reproductive organs. Emerging science reveals that metabolic health, inflammation, diet, and exposure to environmental toxins all play a profound role in hormonal balance, egg and sperm quality, and even early embryo development. Key drivers of dysfunction—such as ultra-processed food, insulin resistance, gut imbalances, and mitochondrial damage—are rarely addressed in conventional fertility care, despite their deep impact. Paying attention to these overlooked root causes offers not only a powerful path to improving fertility but also the foundation for lifelong health in both parents and their future children. In this episode, I discuss, along with Kelly LeVeque, what we can do to improve our fertility, which ultimately impacts the future health of our children. Kelly LeVeque is a holistic nutritionist, celebrity health coach, the best-selling author of Body Love and Body Love Every Day, and most importantly, mom of three little boys. Kelly LeVeque is passionate about the science of human nutrition and is always guided by a practical and optimistic approach to wellness. Kelly helps clients improve their health, achieve goals, and develop sustainable habits to live a healthy and balanced life. Kelly is a regular contributor to numerous health, wellness, and lifestyle publications. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: Fertility in Crisis: Exploring the Toxic Threats to Fertility and the Rise in Infertility The Fertility Crisis: Why it’s Happening and How to Fix it Boost Fertility Naturally: Top Foods to Eat

31 Mars 41min

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