#83: The Maverick of Brain Optimization

#83: The Maverick of Brain Optimization

"My lab is interested in pursuing how we can enhance cognition to improve quality of life." - Adam Gazzaley Dr. Adam Gazzaley (@adamgazz) obtained an M.D. and a Ph.D. in Neuroscience at the Mount Sinai School of Medicine in New York, then postdoctoral training in cognitive neuroscience at UC Berkeley. He is now the director of the Gazzaley Lab at UC San Francisco, a cognitive neuroscience laboratory. His recent studies go far beyond mere description — he and his lab are exploring neuroplasticity and how we can optimize cognitive abilities, even in healthy adults. So, what happens when you combine cognitive-focused video games with neurofeedback, magnetic and electrical stimulation, and even performance-enhancing drugs? Well, that’s just one of many things we cover in this conversation. As someone with Alzheimer's disease and Parkinson's disease on both sides of my family, I find Adam's work to be of incredible importance and promise. I hope this discussion blows your mind, in the best way possible. Enjoy! Show notes, links, and resources can be found at fourhourworkweek.com/podcast This podcast is brought to you by a new sponsor, LegalZoom. Matt Mullenweg (CEO of Automattic - now worth more than a billion dollars) first incorporated his company on LegalZoom. LegalZoom, which I've used myself, can help you with almost anything legal, including setting up a will, doing a proper trademark search, forming an LLC, setting up a non-profit, or finding simple cease-and-desist letter templates. LegalZoom is not a law firm, but they do have a network of independent attorneys available in most states. They can give you advice on the best way to get started, provide contract review, and otherwise help you run your business. Use the code "Tim" at checkout to get $10 off your next order. Take a gander at everything you can get for a fraction of what you'd expect -- LegalZoom.com This podcast is also brought to you by 99Designs, the world’s largest marketplace of graphic designers. Did you know I used 99Designs to rapid prototype the cover for The 4-Hour Body? Here are some of the impressive results. Click this link and get a free $99 upgrade. Give it a test run.. Thanks for listening!

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#847: Steve Young, from Super Bowl MVP to Managing Billions – Hall of Fame 49ers Quarterback on High Performance, Reinvention, Faith, and How to Blend Dreams and Plans

#847: Steve Young, from Super Bowl MVP to Managing Billions – Hall of Fame 49ers Quarterback on High Performance, Reinvention, Faith, and How to Blend Dreams and Plans

Steve Young (@steveyoung) is a Hall of Fame NFL quarterback who played more than 15 seasons, primarily with the San Francisco 49ers. Steve co-founded HGGC, which manages more than $6.9B in capital com...

14 Jan 1h 49min

#846: Permission to Do Nothing — Guided Meditation with Zen Master Henry Shukman

#846: Permission to Do Nothing — Guided Meditation with Zen Master Henry Shukman

This episode is part of a series called Meditation Monday. The teacher, Henry Shukman, has been on my podcast twice before. He is one of only a few dozen masters in the world authorized to teach Sanbo...

12 Jan 9min

#845: How to Use Ketosis for Enhanced Mood, Cognition, and Long-Term Brain Protection — A Practical and Tactical Guide with Dr. Dominic D'Agostino (Plus: Deconstructing Tim’s Latest Keto Experiment)

#845: How to Use Ketosis for Enhanced Mood, Cognition, and Long-Term Brain Protection — A Practical and Tactical Guide with Dr. Dominic D'Agostino (Plus: Deconstructing Tim’s Latest Keto Experiment)

Dr. Dominic D’Agostino (@DominicDAgosti2) is a tenured associate professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine and...

7 Jan 2h 21min

#844: Be Still — Guided Meditation with Zen Master Henry Shukman

#844: Be Still — Guided Meditation with Zen Master Henry Shukman

This episode is part of a series called Meditation Monday. The teacher, Henry Shukman, has been on my podcast twice before. He is one of only a few dozen masters in the world authorized to teach Sanbo...

5 Jan 8min

#843: Tactics and Strategies for a 2026 Reboot — Essentialism and Greg McKeown (Repost)

#843: Tactics and Strategies for a 2026 Reboot — Essentialism and Greg McKeown (Repost)

Greg McKeown is the author of two New York Times bestsellers, Essentialism: The Disciplined Pursuit of Less and Effortless: Make It Easier to Do What Matters Most. 200,000 people receive his weekly 1-...

1 Jan 1h 47min

#842: The Story Behind EpiPen, The Rise of Food Allergies, and What Doctors Got Wrong

#842: The Story Behind EpiPen, The Rise of Food Allergies, and What Doctors Got Wrong

This time around, we have an experimental format, featuring the first episode of a brand-new podcast launching next week, Drug Story. I rarely feature episodes from other shows, but I think this one i...

30 Dec 202558min

#841: Arthur Brooks — Finding The Meaning of Your Life, The Poet's Protocol, The Holy Half-Hour, and Why Your Suffering is Sacred

#841: Arthur Brooks — Finding The Meaning of Your Life, The Poet's Protocol, The Holy Half-Hour, and Why Your Suffering is Sacred

Arthur C. Brooks is a professor at the Harvard Kennedy School and the Harvard Business School, where he teaches courses on leadership and happiness. His next book, The Meaning of Your Life: Finding Pu...

23 Dec 20252h 10min

#840: Bill Gurley — Investing in The AI Era, 10 Days in China, and Important Life Lessons from Bob Dylan, Jerry Seinfeld, MrBeast, and More

#840: Bill Gurley — Investing in The AI Era, 10 Days in China, and Important Life Lessons from Bob Dylan, Jerry Seinfeld, MrBeast, and More

Bill Gurley (@bgurley) is a general partner at Benchmark, a leading venture capital firm in Silicon Valley. His new book is Runnin’ Down a Dream: How to Thrive in a Career You Actually Love.This episo...

17 Dec 20252h 10min

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