HealthTree Podcast for AML: Gabriela Hobbs, MD, Massachusetts General Hospital

HealthTree Podcast for AML: Gabriela Hobbs, MD, Massachusetts General Hospital

Allogeneic stem cell transplantation is the only curative option for patients battling acute myeloid leukemia. However, a significant number of patients will relapse after transplant. Innovative research and therapies are needed in order to improve outcomes in AML patients. The drug Jakafi (ruxolitinib), a kinase inhibitor, is being explored in a current clinical trial as it may help reduce the risk of relapse. Other therapies such as pre-emptive donor lymphocyte infusions, hypomethylating agents and FLT3 inhibitors combined with donor lymphocyte infusions, CAR T-cell and CAR-NK cells are some of the options being explored. Join us live on Wednesday, October 5th at 1:30 pm EST to hear from Dr. Gabriela Hobbs with Massachusetts General Hospital who will be discussing her clinical trial using Jakafi (ruxolitinib) after allogeneic stem cell transplant as well as other therapies to reduce relapse risk. There will be time at the end of the show to ask Dr. Hobbs your questions directly! Thank you to our episode sponsor, Bristol Myers Squibb.

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HealthTree Podcast for AML: Eytan Stein, MD, Memorial Sloan Kettering

HealthTree Podcast for AML: Eytan Stein, MD, Memorial Sloan Kettering

The IDH mutation can be found in approximately 20% of adult AML cases. Isocitrate dehydrogenase isoform 1 and 2 or IDH1 and IDH2 mutations are typically found in older AML patients and have an interme...

24 Aug 202258min

Digging Deeper Into the TP53 Mutation in AML with Rory Shallis, MD, Yale

Digging Deeper Into the TP53 Mutation in AML with Rory Shallis, MD, Yale

The TP53 mutation in AML is considered to be a high risk mutation and occurs in approximately 5-10% of patients. This genetic mutation has been difficult to treat, often being chemoresistant with a po...

14 Juli 20221h 1min

HealthTree Podcast for AML: Dr. Jane Liesveld, University of Rochester

HealthTree Podcast for AML: Dr. Jane Liesveld, University of Rochester

The FLT3 gene mutation is the most common mutation seen in acute myeloid leukemia patients. It occurs in up to 37% of adult patients with AML. FLT3 mutations have been harder to treat with poor outcom...

29 Juni 20221h

HealthTree Podcast for AML: Dr. Kendra Sweet, Moffitt Cancer Center

HealthTree Podcast for AML: Dr. Kendra Sweet, Moffitt Cancer Center

Immunotherapy continues to be an expanding and evolving area of research for AML with many drugs in development. One drug currently being studied is IMGN632, an antibody drug conjugate, that targets C...

9 Juni 202258min

HealthTree Podcast for AML: Dr. Joseph Jurcic, Columbia University

HealthTree Podcast for AML: Dr. Joseph Jurcic, Columbia University

Immunotherapy is one of the most promising areas of cancer research. Drugs like checkpoint inhibitors, monoclonal and bispecific anitbodies, antibody drug conjugates and CAR-T cell therapy are all ext...

26 Maj 20221h 1min

HealthTree Radio for AML:  Margaret Kasner, MD, Thomas Jefferson University

HealthTree Radio for AML: Margaret Kasner, MD, Thomas Jefferson University

About 30% of acute myeloid leukemia patients have developed a mutation in the FLT3 gene. Up until recently, this specific mutation usually resulted in poor treatment outcomes. Today, we have several d...

7 Feb 202256min

HealthTree Radio for AML: Eytan Stein, MD, Memorial Sloan Kettering

HealthTree Radio for AML: Eytan Stein, MD, Memorial Sloan Kettering

There is a tremendous amount of progress being made in AML. It was remarkable to see the significant work being done in the field of AML at the recent American Society of Hematology (ASH) conference i...

2 Feb 20221h 5min

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