The MS Show4 Aug 2020

020 Multiple Sclerosis - Laura Piccio Latest Research on Intermittent Fasting and MS

Laura (and team)'s research in animal models of Multiple Sclerosis has revealed some interesting benefits of diet - specifically intermittent fasting.

This research progressed to a small-group human pilot study which produced outcomes akin to the animal study. It identified that intermittent fasting, if done under the observation of a dietician, is safe for people with MS. In this case the approach taken was alternate day fasting.

The improvement in blood markers seen in the animal study which are associated with inflammation, was also evidenced in the human pilot.

Laura is presently involved in a larger scale human study which is exploring caloric-reduced intermittent fasting, similar in approach to the 5:2 approach. Once again this is under the watchful eye of a dietician. The team is looking at the gut microbiome and blood inflammatory markers.

What becomes clear as we talk is the difficulty of conducting research amongst patients who are experiencing MS symptoms. There is clearly a desire on behalf of both the patient and researcher to ensure recovery from a relapse is not prevented. This makes it difficult to identify the degree to which, if any, fasting contributes to the improvement (or maybe the steroid treatment brought about the improvement).

Laura is keen to point out that she doesn't believe diet can cure MS. Diet is a part of the range of beneficial approaches. You cannot base all your decisions on the stories of others that have no scientific backing.

Epidemiological studies show obesity in children and young adults is associated with an increased risk to develop MS.

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Copyright : Multiple Success 2020

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