#113 Appetite, Insulin, Leptin, and mTOR with Omar Mohtar MD PhD

#113 Appetite, Insulin, Leptin, and mTOR with Omar Mohtar MD PhD

You might have heard conflicting opinions about what causes obesity and overeating. Part of it is blamed on calories, part of it on satiety signaling through this hormone called leptin. However, there is so much more context to how these pathways take effect. Welcome to the Body Mind Empowerment Podcast I’m your host Siim Land and our guest today is Omar Mohtar. Omar is an MD PhD student at the Boston University in Molecular Medicine. He’s published papers on treating lung cancer, cell disease, leptin, and mTOR. Timestamps: How Omar Started Researching Leptin 01:30 How Does mTOR Affect Satiety 04:00 Context of mTOR Activation in Different Diets 10:50 How Processed Food Hijack Your Brain 16:30 How Does Insulin Regulate Leptin 20:30 Ketogenic Diets and Appetite 28:02 The Brain's Role in Regulating Appetite 34:30 Fasting and Leptin Sensitivity 42:15 Fasting and Overeating 50:55 Danger of Interpreting Animal Studies 01:05:00 And much more... Here are the links to the podcast on all platforms Link to the Audio Podcast on iTunes and Stitcher Link to the podcast on Spotify Link to the podcast on CastBox If you want to support this podcast, then I'd greatly appreciate if you could join my Patreon community. You'll be able to get access to unique worksheets about Body Mind Empowerment, a lot of exclusive videos about my routines, biohacking workshops, and a privilege for your questions on the next Q&A. Click Here to Support the Show on Patreon! Show Notes Omar's Paper on mTOR and Leptin Metabolic Autophagy Master Class Video Course My NEW BOOK Metabolic Autophagy Get the FULL GUIDE to INTERMITTENT FASTING FREE BOOK Get the Metabolic Autophagy Program Keto Adaptation Manual Book Watch the Biohacking Bootcamp Videos on Patreon Use the Code SIIM for a 10% discount on BluBlox Glasses Use the Code redsiim at Redlightrising.co.uk Body Mind Empowerment Handbook Keto Fit Program Keto // IF Program P.S. The HD video recordings of all the Biohacker Summit Tallinn speeches are now released. Incredible information about optimizing your health and well-being. My own speech talks about doing fasting with training for longevity and muscle growth. Check it out! Stay Empowered Siim

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#478 Mitochondria Scientist: The Only Proven Way to Extend Human Lifespan - Dr Mark Tarnopolsky

#478 Mitochondria Scientist: The Only Proven Way to Extend Human Lifespan - Dr Mark Tarnopolsky

Dr. Mark Tarnopolsky is a Professor and Division Head of Neuromuscular and Neurometabolic Disorders in the Department of Pediatrics at McMaster University. He completed a PhD in Cell Biology and Metab...

8 Nov 202559min

#477 The Science of Longevity Genes: What We’ve Learned from Centenarians - Dr Tyler Panzner

#477 The Science of Longevity Genes: What We’ve Learned from Centenarians - Dr Tyler Panzner

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:48 The genetics of a 117-year-old woman08:16 Resilience, immunity and longev...

31 Okt 20251h

#476 Siim Land on Human Immortality, Gene Editing, Biomarkers - The Beyond Tomorrow Podcast

#476 Siim Land on Human Immortality, Gene Editing, Biomarkers - The Beyond Tomorrow Podcast

Timestamps0:00 – Introduction4:12 – Humans adapt, and that changes the rules9:58 – Diet diversity, sensitivities, and n of 116:51 – Assess first: biomarkers that predict disease risk18:27 – Fixing sle...

24 Okt 20251h 6min

#475 Q&A: Biggest things that contribute to my health, does caffeine age the brain, can you make up for lost sleep and more

#475 Q&A: Biggest things that contribute to my health, does caffeine age the brain, can you make up for lost sleep and more

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Does exercise increase inflammation03:03 Melatonin megadosing research04:23 NOVOS vs...

18 Okt 202547min

#474 Longevity Supplements Ranked From Best to Worst

#474 Longevity Supplements Ranked From Best to Worst

Get my 2025 supplement guide: https://www.siimland.co/supplement-list-2025Timestamps:00:00 Intro00:14 Taurine01:19 Apigenin01:55 Resveratrol03:20 Rapamycin04:55 Metformin06:11 Calcium AKG07:30 Melaton...

10 Okt 202537min

#473 Tech Expert: Why Life Speeds Up As You Age (And How To Slow It Down!)

#473 Tech Expert: Why Life Speeds Up As You Age (And How To Slow It Down!)

Chris Dancy is called 'the most connected man on Earth' because of his pioneering use of technology in everyday life and health optimization.Check out Bon Charge wellness products (Code SIIM for 15% d...

4 Okt 20251h 2min

#472 Scientist Reveals the Hidden Program of Aging and How to Control It - Josh Mitteldorf PhD

#472 Scientist Reveals the Hidden Program of Aging and How to Control It - Josh Mitteldorf PhD

Josh Witteldorf is a PhD in physics who pivoted to researching aging and investigated the evolutionary reasons for aging and human lifespan. He's written the book Cracking the Aging Code.Check out Bon...

26 Sep 20251h 20min

#471 Ranking 100 Health Biomarkers (Most to Least Important)

#471 Ranking 100 Health Biomarkers (Most to Least Important)

Get my free bloodwork cheat sheet: https://www.siimland.co/bloodwork-cheat-sheetTimestamps:00:00 Intro00:32 Resting heart rate02:27 hsCRP03:32 VLDL03:52 LDL particle count04:31 Homocysteine 05:26 Resp...

20 Sep 20251h 43min

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