#257 Slowing Aging with Sirtuins, NAD and Others - Dr Vera Gorbunova
Siim Land Podcast19 Juli 2021

#257 Slowing Aging with Sirtuins, NAD and Others - Dr Vera Gorbunova

Welcome to the Siim Land Podcast I’m your host Siim Land and today our guest is Dr. Vera Gorbunova. Vera is a Professor of Biology at the University of Rochester and a co-director of the Rochester Aging Research Center. She has published over 100 publications about longevity, sirtuins, and aging. This episode is brought to you by DoNotAge.org. DoNotAge offers different kinds of molecules as supplements that have been seen to have a longevity benefit, such as NMN, trimethylglycine, apigenin, and hyaluronic acid. They recently came out with the world’s first at-home NAD level testing kit as well as a SIRT6 activator. Dr. Vera is one of the advisors of DoNotAge and I’m taking their products as well. You can get a small 5% discount at donotage.org if you use the code SIIM. Timestamps: 01:10 How Vera Became a Longevity Scientist 05:00 What Causes Aging 08:45 What Speeds Up Aging 10:39 Telomeres and DNA Repair 13:00 Sirtuins and Longevity 16:35 How Sirtuins Work 19:05 Human Research in Sirtuins 26:56 NAD+ and Sirtuins 32:17 How the Body Produces NAD 38:08 Hyaluronic Acid Benefits 44:45 New Compounds for Aging 47:20 Rapamycin and Metformin And much more Here are the links to the podcast on all platforms Link to the Audio Podcast on iTunes and Stitcher Link to the podcast on Spotify Link to the podcast on CastBox Watch the Biohacking Bootcamp Videos on Patreon This episode is sponsored by BiOptimizers. They're giving the listeners of this podcast an exclusive offer on one of their best-selling products. It's called Magnesium Breakthrough and is the most full-spectrum magnesium supplement out there. Most supplements contain only 1 or 2 forms of magnesium... when in reality there are at least 7 that your body needs and benefits from. Magnesium is the master mineral that governs virtually all physiological processes in the body. With volume discounts combined with our custom 10% coupon code, SIIM10, you can save up to 40% off select packages of Magnesium Breakthrough! That’s an AMAZING value. And I promise that deal is ONLY available on this specific website, Click Here to Support the Show on Patreon! Show Notes DoNotAge SIRT6 Activator - Use Code SIIM DoNotAge - Use Code SIIM Lucas Aoun's Natural Testosterone Optimization Course 10% OFF The Immunity Fix on Amazon Get Magnesium Breakthrough for a 10% Discount! Use Code SIIM for 10% Off Self Decode Use Code SIIM for a 10% Discount on the KAATSU Bands My New Book Stronger by Stress My NEW BOOK Metabolic Autophagy Metabolic Autophagy Audiobook Metabolic Autophagy Master Class Total Sleep Optimization Video Course Get the FULL GUIDE to INTERMITTENT FASTING FREE BOOK Get the Metabolic Autophagy Program Keto Adaptation Manual Book Watch the Biohacking Bootcamp Videos on Patreon Body Mind Empowerment Handbook Keto Fit Program Keto // IF Program Stay Empowered Siim

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#483 Q&A Training fast twitch muscle fibers instead of lifting weights, How much protein for longevity, My all out supplement stack

#483 Q&A Training fast twitch muscle fibers instead of lifting weights, How much protein for longevity, My all out supplement stack

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 What level of sports performance is unhealthy04:15 How much protein is bad for aging...

13 Dec 202551min

#482 Why Scientists Believe Lithium May Be a Longevity Molecule

#482 Why Scientists Believe Lithium May Be a Longevity Molecule

Jon Berner, MD PhD is a board certified Psychiatrist from Seattle with 27 years of experience. He's also published several scientific papers.Check out Bon Charge wellness products (Code SIIM for 15% d...

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#481 The Anti-Aging Pill Chinese Scientists Are Developing - Aiming for 120+ Lifespans - Yip Tszho

#481 The Anti-Aging Pill Chinese Scientists Are Developing - Aiming for 120+ Lifespans - Yip Tszho

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandYip (Zico) Tszho is the Chief Executive of Lonvi Biosciences, a longevity-drug start-up, in Shenzhen,...

29 Nov 202559min

#480 The Science of Saunas: How Heat Boosts Fitness & Longevity - Brady Holmer MSc

#480 The Science of Saunas: How Heat Boosts Fitness & Longevity - Brady Holmer MSc

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandBrady Holmer is a science writer and researcher with a Master's degree in Human Performance from the ...

21 Nov 202559min

#479 Longevity Testing 101: What Really Matters (with Siim Land and Dr. Joy Kong)

#479 Longevity Testing 101: What Really Matters (with Siim Land and Dr. Joy Kong)

Join our upcoming retreat in January 2026: https://www.siimland.co/retreat Timestamps:Introduction (00:00)Discussion on longevity clinics and testing (01:52)Essential health tests and biomarkers (05:4...

14 Nov 20251h 4min

#478 Mitochondria Scientist: The Only Proven Way to Extend Human Lifespan - Dr Mark Tarnopolsky

#478 Mitochondria Scientist: The Only Proven Way to Extend Human Lifespan - Dr Mark Tarnopolsky

Dr. Mark Tarnopolsky is a Professor and Division Head of Neuromuscular and Neurometabolic Disorders in the Department of Pediatrics at McMaster University. He completed a PhD in Cell Biology and Metab...

8 Nov 202559min

#477 The Science of Longevity Genes: What We’ve Learned from Centenarians - Dr Tyler Panzner

#477 The Science of Longevity Genes: What We’ve Learned from Centenarians - Dr Tyler Panzner

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:48 The genetics of a 117-year-old woman08:16 Resilience, immunity and longev...

31 Okt 20251h

#476 Siim Land on Human Immortality, Gene Editing, Biomarkers - The Beyond Tomorrow Podcast

#476 Siim Land on Human Immortality, Gene Editing, Biomarkers - The Beyond Tomorrow Podcast

Timestamps0:00 – Introduction4:12 – Humans adapt, and that changes the rules9:58 – Diet diversity, sensitivities, and n of 116:51 – Assess first: biomarkers that predict disease risk18:27 – Fixing sle...

24 Okt 20251h 6min

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