#413 Longevity Scientist Breaks Down What Causes Aging of Cells - Matt Kaeberlein PhD

#413 Longevity Scientist Breaks Down What Causes Aging of Cells - Matt Kaeberlein PhD

Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland

Timestamps:

  • 01:00 Senescent Cells and Aging
  • 09:18 Bon Charge Sponsorship
  • 10:00 Immune System Aging
  • 15:08 What Triggers Cell Senescence
  • 18:50 How to Measure Cell Senescence
  • 22:58 Senolytic Supplements and Drugs
  • 35:50 mTOR, Rapamycin and Senescence
  • 38:25 Aging and Autoimmunity
  • 46:00 Recent Study on IL-11 and Life Extension
  • 55:00 Mice Living Pathogen Free in Labs

Matt Kaeberlein Optispan YouTube Channel: https://www.youtube.com/@optispan

Get my new book The Longevity Leap: https://www.siimland.co/thelongevityleap

Avsnitt(485)

#262 The 5 Longevity Breakthroughs That Will Help You Reverse Age - Dr Melissa Petersen

#262 The 5 Longevity Breakthroughs That Will Help You Reverse Age - Dr Melissa Petersen

Welcome to the Siim Land Podcast I’m your host Siim Land and our guest today is Dr. Melissa Petersen. Dr. Melissa is an epigenetic success coach and licensed chiropractic with board certification in holistic health. I was also speaking at Dr. Melissa’s free online event the Longevity Summit with other experts from the anti-aging field. Check out the free Longevity Summit at siimland.com/262 Timestamps: 03:00 What Does Longevity Mean 09:00 Understanding Aging Mechanisms 11:55 Epigenetics vs Genetics 17:08 Perception's Effect on Aging 23:58 Virtual Reality and Psychedelics 34:00 Do Traumas Pass On Through Genes 40:45 Wearable Technologies 45:45 Immune System Aging 51:40 What to Do With Increased Lifespan And much more... Here are the links to the podcast on all platforms Link to the Audio Podcast on iTunes and Stitcher Link to the podcast on Spotify Link to the podcast on CastBox Watch the Biohacking Bootcamp Videos on Patreon This episode is sponsored by BiOptimizers. They're giving the listeners of this podcast an exclusive offer on one of their best-selling products. It's called Magnesium Breakthrough and is the most full-spectrum magnesium supplement out there. Most supplements contain only 1 or 2 forms of magnesium... when in reality there are at least 7 that your body needs and benefits from. Magnesium is the master mineral that governs virtually all physiological processes in the body.  With volume discounts combined with our custom 10% coupon code, SIIM10, you can save up to 40% off select packages of Magnesium Breakthrough! That’s an AMAZING value. And I promise that deal is ONLY available on this specific website,  Click Here to Support the Show on Patreon!   Show Notes DoNotAge SIRT6 Activator - Use Code SIIM DoNotAge - Use Code SIIM Lucas Aoun's Natural Testosterone Optimization Course 10% OFF The Immunity Fix on Amazon Get Magnesium Breakthrough for a 10% Discount! Use Code SIIM for 10% Off Self Decode Use Code SIIM for a 10% Discount on the KAATSU Bands My New Book Stronger by Stress My NEW BOOK Metabolic Autophagy Metabolic Autophagy Audiobook Metabolic Autophagy Master Class Total Sleep Optimization Video Course Get the FULL GUIDE to INTERMITTENT FASTING FREE BOOK Get the Metabolic Autophagy Program Keto Adaptation Manual Book Watch the Biohacking Bootcamp Videos on Patreon Body Mind Empowerment Handbook Keto Fit Program Keto // IF Program Stay Empowered Siim

23 Aug 202157min

#261 Optimizing Physical and Mental Performance - Olli Sovijärvi, Teemu Arina and Siim Land Live Q&A

#261 Optimizing Physical and Mental Performance - Olli Sovijärvi, Teemu Arina and Siim Land Live Q&A

In this episode, we're on the Biohacker Summit Live Show with Teemu Arina and Dr Olli Sovijärvi.    Here are the links to the podcast on all platforms Link to the Audio Podcast on iTunes and Stitcher Link to the podcast on Spotify Link to the podcast on CastBox Watch the Biohacking Bootcamp Videos on Patreon This episode is sponsored by BiOptimizers. They're giving the listeners of this podcast an exclusive offer on one of their best-selling products. It's called Magnesium Breakthrough and is the most full-spectrum magnesium supplement out there. Most supplements contain only 1 or 2 forms of magnesium... when in reality there are at least 7 that your body needs and benefits from. Magnesium is the master mineral that governs virtually all physiological processes in the body.  With volume discounts combined with our custom 10% coupon code, SIIM10, you can save up to 40% off select packages of Magnesium Breakthrough! That’s an AMAZING value. And I promise that deal is ONLY available on this specific website,  Click Here to Support the Show on Patreon!   Show Notes DoNotAge SIRT6 Activator - Use Code SIIM DoNotAge - Use Code SIIM Lucas Aoun's Natural Testosterone Optimization Course 10% OFF The Immunity Fix on Amazon Get Magnesium Breakthrough for a 10% Discount! Use Code SIIM for 10% Off Self Decode Use Code SIIM for a 10% Discount on the KAATSU Bands My New Book Stronger by Stress My NEW BOOK Metabolic Autophagy Metabolic Autophagy Audiobook Metabolic Autophagy Master Class Total Sleep Optimization Video Course Get the FULL GUIDE to INTERMITTENT FASTING FREE BOOK Get the Metabolic Autophagy Program Keto Adaptation Manual Book Watch the Biohacking Bootcamp Videos on Patreon Body Mind Empowerment Handbook Keto Fit Program Keto // IF Program Stay Empowered Siim

18 Aug 20211h 3min

#260 Antifragility, Daily Routines and Stacking Biohacks - Siim Land on the Project Red Podcast

#260 Antifragility, Daily Routines and Stacking Biohacks - Siim Land on the Project Red Podcast

Welcome to the Siim Land podcast I’m your host Siim Land and today I’m playing you a replay of me being a guest on the Project Red Podcast. Project Red is run by my friends Bryan and James at Red Light Rising. We talk about all things biohacking, routines, and stress resilience. You can also check out Red Light Rising’s red light devices at redlightrising.co.uk and use the code REDSIIM for a 5% discount. Timestamps: 02:45 How Siim Got Into Health and Biohacking 07:00 What Is Biohacking 09:45 Siim's Daily Routines 14:34 Should You Have a Morning Routine 23:00 Antifragility and Fragility 26:30 Meal Timing and Circadian Rhythms 32:00 One Meal a Day 40:30 Getting Good Sleep 48:28 Blood Flow Restriction Training 52:00 Stacking Biohacks 58:00 Fasting After a Workout 01:01:40 Dangerous Things People Do 01:07:15 Biohacking Around Other People 01:12:45 Biohacks for Air Travel And much more Here are the links to the podcast on all platforms Link to the Audio Podcast on iTunes and Stitcher Link to the podcast on Spotify Link to the podcast on CastBox Watch the Biohacking Bootcamp Videos on Patreon This episode is sponsored by BiOptimizers. They're giving the listeners of this podcast an exclusive offer on one of their best-selling products. It's called Magnesium Breakthrough and is the most full-spectrum magnesium supplement out there. Most supplements contain only 1 or 2 forms of magnesium... when in reality there are at least 7 that your body needs and benefits from. Magnesium is the master mineral that governs virtually all physiological processes in the body.  With volume discounts combined with our custom 10% coupon code, SIIM10, you can save up to 40% off select packages of Magnesium Breakthrough! That’s an AMAZING value. And I promise that deal is ONLY available on this specific website,  Click Here to Support the Show on Patreon!   Show Notes DoNotAge SIRT6 Activator - Use Code SIIM DoNotAge - Use Code SIIM Lucas Aoun's Natural Testosterone Optimization Course 10% OFF The Immunity Fix on Amazon Get Magnesium Breakthrough for a 10% Discount! Use Code SIIM for 10% Off Self Decode Use Code SIIM for a 10% Discount on the KAATSU Bands My New Book Stronger by Stress My NEW BOOK Metabolic Autophagy Metabolic Autophagy Audiobook Metabolic Autophagy Master Class Total Sleep Optimization Video Course Get the FULL GUIDE to INTERMITTENT FASTING FREE BOOK Get the Metabolic Autophagy Program Keto Adaptation Manual Book Watch the Biohacking Bootcamp Videos on Patreon Body Mind Empowerment Handbook Keto Fit Program Keto // IF Program Stay Empowered Siim

10 Aug 20211h 23min

#259 Q&A - Best Exercises for Nutrient Partitioning, Red Light Therapy for Skin and More

#259 Q&A - Best Exercises for Nutrient Partitioning, Red Light Therapy for Skin and More

Welcome to the Siim Land podcast I’m your host Siim Land and today we have a YouTube live Q&A session. I answer different kinds of questions about health, fitness, and biohacking. Unfortunately, there was a bit of an echo in the live recording for some reason so I apologize for that but the information itself is pretty good. So, I hope you still enjoy this episode. This episode is brought to you by DoNotAge.org. DoNotAge offers different kinds of molecules as supplements that have been seen to have a longevity benefit, such as NMN, trimethylglycine, apigenin, and hyaluronic acid. They recently came out with the world’s first at-home NAD level testing kit as well as a SIRT6 activator. Dr. Vera is one of the advisors of DoNotAge and I’m taking their products as well. You can get a small 5% discount at donotage.org if you use the code SIIM.   Here are the links to the podcast on all platforms Link to the Audio Podcast on iTunes and Stitcher Link to the podcast on Spotify Link to the podcast on CastBox Watch the Biohacking Bootcamp Videos on Patreon This episode is sponsored by BiOptimizers. They're giving the listeners of this podcast an exclusive offer on one of their best-selling products. It's called Magnesium Breakthrough and is the most full-spectrum magnesium supplement out there. Most supplements contain only 1 or 2 forms of magnesium... when in reality there are at least 7 that your body needs and benefits from. Magnesium is the master mineral that governs virtually all physiological processes in the body.  With volume discounts combined with our custom 10% coupon code, SIIM10, you can save up to 40% off select packages of Magnesium Breakthrough! That’s an AMAZING value. And I promise that deal is ONLY available on this specific website,  Click Here to Support the Show on Patreon!   Show Notes DoNotAge SIRT6 Activator - Use Code SIIM DoNotAge - Use Code SIIM Lucas Aoun's Natural Testosterone Optimization Course 10% OFF The Immunity Fix on Amazon Get Magnesium Breakthrough for a 10% Discount! Use Code SIIM for 10% Off Self Decode Use Code SIIM for a 10% Discount on the KAATSU Bands My New Book Stronger by Stress My NEW BOOK Metabolic Autophagy Metabolic Autophagy Audiobook Metabolic Autophagy Master Class Total Sleep Optimization Video Course Get the FULL GUIDE to INTERMITTENT FASTING FREE BOOK Get the Metabolic Autophagy Program Keto Adaptation Manual Book Watch the Biohacking Bootcamp Videos on Patreon Body Mind Empowerment Handbook Keto Fit Program Keto // IF Program Stay Empowered Siim

3 Aug 202155min

#258 Artificial Intelligence for Genetic Testing and DNA Analysis - Joe Cohen

#258 Artificial Intelligence for Genetic Testing and DNA Analysis - Joe Cohen

Welcome to the Siim Land Podcast I’m your host Siim Land and today our guest is Joe Cohen. Joe is the founder and CEO of selfhacked.com and Self Decode. Self Decode is a genetics decoding company. You can get personalized health recommendations based on your DNA and the latest scientific research. They have numerous different DNA reports for different areas of focus like weight loss, longevity, gastrointestinal health, cognition, and even mood. Recently Self Decode came out with their 2.0 software that incorporates artificial intelligence in generating DNA reports. It’s the most advanced and comprehensive consumer DNA service in the world. You can get a 10% discount with the code SIIM at get.selfdecode.com/siim Head over to get.selfdecode.com/siim and use the code SIIM for a 10% discount on your personalized DNA reports. Timestamps: What's New in Genetic Testing 01:05 Artificial Intelligence for DNA Reports 06:30 How Big of a Role Do Genes Have 12:37 Biohacking Mood 16:28 New Things Joe Has Learned About His Genes 19:56 Joe's Mood Hacking Results 24:00 Do DNA Test Now or Later 30:58 Self Decode 2.0 Walkthrough 37:00 What Is Joe Working on His Genetics 41:45 Data Safety and Regulations 48:00 Understanding Your DNA Results 50:00 How Most DNA Companies Are Cutting Corners 56:00 And much more... Here are the links to the podcast on all platforms Link to the Audio Podcast on iTunes and Stitcher Link to the podcast on Spotify Link to the podcast on CastBox Watch the Biohacking Bootcamp Videos on Patreon   With SelfDecode you now have access to deep knowledge about your genetics and uniqueness. It's an invaluable tool for anyone wanting to custom tailor their diet, exercise, supplementation and self-care. You can get personalized health recommendations based on your DNA and the latest scientific research. They have numerous different DNA reports for different areas of focus like weight loss, longevity, gastrointestinal health, cognition, and even COVID19. I love SelfDecode and I advise everyone to get it. You can get a 10% discount with the code SIIM at get.selfdecode.com/siim Head over to get.selfdecode.com/siim and use the code SIIM for a 10% discount on your personalized DNA reports. Show Notes Use Code SIIM for 10% Off Self Decode Joe Cohen Instagram Use Code SIIM for a 10% Discount on the KAATSU Bands My New Book Stronger by Stress My NEW BOOK Metabolic Autophagy Metabolic Autophagy Audiobook Metabolic Autophagy Master Class Total Sleep Optimization Video Course Get the FULL GUIDE to INTERMITTENT FASTING FREE BOOK Get the Metabolic Autophagy Program Keto Adaptation Manual Book Watch the Biohacking Bootcamp Videos on Patreon Body Mind Empowerment Handbook Keto Fit Program Keto // IF Program Stay Empowered Siim

27 Juli 20211h 3min

#257 Slowing Aging with Sirtuins, NAD and Others - Dr Vera Gorbunova

#257 Slowing Aging with Sirtuins, NAD and Others - Dr Vera Gorbunova

Welcome to the Siim Land Podcast I’m your host Siim Land and today our guest is Dr. Vera Gorbunova. Vera is a Professor of Biology at the University of Rochester and a co-director of the Rochester Aging Research Center. She has published over 100 publications about longevity, sirtuins, and aging. This episode is brought to you by DoNotAge.org. DoNotAge offers different kinds of molecules as supplements that have been seen to have a longevity benefit, such as NMN, trimethylglycine, apigenin, and hyaluronic acid. They recently came out with the world’s first at-home NAD level testing kit as well as a SIRT6 activator. Dr. Vera is one of the advisors of DoNotAge and I’m taking their products as well. You can get a small 5% discount at donotage.org if you use the code SIIM. Timestamps: 01:10 How Vera Became a Longevity Scientist 05:00 What Causes Aging 08:45 What Speeds Up Aging 10:39 Telomeres and DNA Repair 13:00 Sirtuins and Longevity 16:35 How Sirtuins Work 19:05 Human Research in Sirtuins 26:56 NAD+ and Sirtuins 32:17 How the Body Produces NAD 38:08 Hyaluronic Acid Benefits 44:45 New Compounds for Aging 47:20 Rapamycin and Metformin And much more Here are the links to the podcast on all platforms Link to the Audio Podcast on iTunes and Stitcher Link to the podcast on Spotify Link to the podcast on CastBox Watch the Biohacking Bootcamp Videos on Patreon This episode is sponsored by BiOptimizers. They're giving the listeners of this podcast an exclusive offer on one of their best-selling products. It's called Magnesium Breakthrough and is the most full-spectrum magnesium supplement out there. Most supplements contain only 1 or 2 forms of magnesium... when in reality there are at least 7 that your body needs and benefits from. Magnesium is the master mineral that governs virtually all physiological processes in the body.  With volume discounts combined with our custom 10% coupon code, SIIM10, you can save up to 40% off select packages of Magnesium Breakthrough! That’s an AMAZING value. And I promise that deal is ONLY available on this specific website,  Click Here to Support the Show on Patreon!   Show Notes DoNotAge SIRT6 Activator - Use Code SIIM DoNotAge - Use Code SIIM Lucas Aoun's Natural Testosterone Optimization Course 10% OFF The Immunity Fix on Amazon Get Magnesium Breakthrough for a 10% Discount! Use Code SIIM for 10% Off Self Decode Use Code SIIM for a 10% Discount on the KAATSU Bands My New Book Stronger by Stress My NEW BOOK Metabolic Autophagy Metabolic Autophagy Audiobook Metabolic Autophagy Master Class Total Sleep Optimization Video Course Get the FULL GUIDE to INTERMITTENT FASTING FREE BOOK Get the Metabolic Autophagy Program Keto Adaptation Manual Book Watch the Biohacking Bootcamp Videos on Patreon Body Mind Empowerment Handbook Keto Fit Program Keto // IF Program Stay Empowered Siim

19 Juli 202152min

#256 Testosterone Replacement Therapy and Optimization - Saad Alam

#256 Testosterone Replacement Therapy and Optimization - Saad Alam

Welcome to the Siim Land Podcast I’m your host Siim Land and our guest today is Saad Alam. Saad is an entrepreneur from the US and the founder and CEO of Hone. Hone is an online clinic specialized in male hormone optimization and health. In this episode, we’re going to talk about how to improve your testosterone and vitality. This episode is brought to you by Kaatsu Training. Kaatsu Bands incorporate blood flow moderation training that tricks the body into thinking it’s lifting heavier weights than it actually is. When traditional weightlifting requires you to reach 70-80% of your 1 repetition maximum to stimulate muscle hypertrophy, then Kaatsu bands achieve that effect only at 20-30%. So, it’s perfect for treating injuries or used when you don’t have access to heavier weights. Research about Kaatsu bands also shows it lowers blood pressure, speeds up recovery from injuries, releases stem cells, builds muscle, burns fat, and prevents age-related muscle loss. These things are amazing and I use them almost every day to recover from my heavier workouts. If you want to try out the Kaatsu bands, then use the code SIIM for a 10% discount at kaatsu-global.com. That’s SIIM at kaatsu-global.com. Timestamps: 01:45 How Saad Started Hone 03:45 Saad's Discovery of Low Testosterone 10:59 Healthspan and Lifespan Difference 14:05 How Saad Fixed His Testosterone Levels 17:35 Thomas Delauer Coaching Saad 22:57 Siim's Current Carb Intake Strategies 24:35 Saad's Workout While Adapting to Keto 27:45 Biggest Causes of Low Testosterone 32:34 How Does Hone TRT Work 41:20 Who Would Be a Good Candidate for TRT 43:23 Do You Have to Stay on TRT for the Rest of Your Life 47:30 Side-Effects of Too Much Testosterone 51:30 Testosterone Creams vs Injections 54:24 Upper Limit for TRT And much more Here are the links to the podcast on all platforms Link to the Audio Podcast on iTunes and Stitcher Link to the podcast on Spotify Link to the podcast on CastBox Watch the Biohacking Bootcamp Videos on Patreon This episode is sponsored by BiOptimizers. They're giving the listeners of this podcast an exclusive offer on one of their best-selling products. It's called Magnesium Breakthrough and is the most full-spectrum magnesium supplement out there. Most supplements contain only 1 or 2 forms of magnesium... when in reality there are at least 7 that your body needs and benefits from. Magnesium is the master mineral that governs virtually all physiological processes in the body.  With volume discounts combined with our custom 10% coupon code, SIIM10, you can save up to 40% off select packages of Magnesium Breakthrough! That’s an AMAZING value. And I promise that deal is ONLY available on this specific website,  Click Here to Support the Show on Patreon!   Show Notes Hone Health Website Saad Alam Instagram Lucas Aoun's Natural Testosterone Optimization Course 10% OFF The Immunity Fix on Amazon Get Magnesium Breakthrough for a 10% Discount! Use Code SIIM for 10% Off Self Decode Use Code SIIM for a 10% Discount on the KAATSU Bands My New Book Stronger by Stress My NEW BOOK Metabolic Autophagy Metabolic Autophagy Audiobook Metabolic Autophagy Master Class Total Sleep Optimization Video Course Get the FULL GUIDE to INTERMITTENT FASTING FREE BOOK Get the Metabolic Autophagy Program Keto Adaptation Manual Book Watch the Biohacking Bootcamp Videos on Patreon Body Mind Empowerment Handbook Keto Fit Program Keto // IF Program Stay Empowered Siim

13 Juli 20211h 2min

#255 Supplements I Am Taking - Siim Land

#255 Supplements I Am Taking - Siim Land

In this episode, I talk about the supplements I am taking.  Watch the video version.  Here are the links to the podcast on all platforms Link to the Audio Podcast on iTunes and Stitcher Link to the podcast on Spotify Link to the podcast on CastBox Watch the Biohacking Bootcamp Videos on Patreon This episode is sponsored by BiOptimizers. They're giving the listeners of this podcast an exclusive offer on one of their best-selling products. It's called Magnesium Breakthrough and is the most full-spectrum magnesium supplement out there. Most supplements contain only 1 or 2 forms of magnesium... when in reality there are at least 7 that your body needs and benefits from. Magnesium is the master mineral that governs virtually all physiological processes in the body.  With volume discounts combined with our custom 10% coupon code, SIIM10, you can save up to 40% off select packages of Magnesium Breakthrough! That’s an AMAZING value. And I promise that deal is ONLY available on this specific website,  Click Here to Support the Show on Patreon!    Magnesium Breakthrough: http://siimland.bioptimize.hop.clickbank.net/?w=mag Do Not Age NMN Use Code SIIM for a 5% Discount: http://www.donotage.org/ Pure Natura Organ Meat Supplements Use Code SIIMLAND: https://purenatura.com/ Get Drink HRW Molecular Hydrogen for 10% OFF With the Code SIIM: https://drinkhrw.com?afmc=SIIM Pure Clinica CoQ10: https://amzn.to/3dZFcp9 Glycine Powder: https://amzn.to/2TSIIL7 Qualia Mind Use Code SIIM for 15% Discount: https://neurohacker.com/?rfsn=4454455.44567d Black Stuff Use Code SIIM: https://www.blackstuff.ee/    Show Notes   The Immunity Fix on Amazon Get Magnesium Breakthrough for a 10% Discount! Use Code SIIM for 10% Off Self Decode Use Code SIIM for a 10% Discount on the KAATSU Bands My New Book Stronger by Stress My NEW BOOK Metabolic Autophagy Metabolic Autophagy Audiobook Metabolic Autophagy Master Class Total Sleep Optimization Video Course Get the FULL GUIDE to INTERMITTENT FASTING FREE BOOK Get the Metabolic Autophagy Program Keto Adaptation Manual Book Watch the Biohacking Bootcamp Videos on Patreon Body Mind Empowerment Handbook Keto Fit Program Keto // IF Program Stay Empowered Siim

10 Juli 202128min

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