Podcast #190: Toradol Dosing

Author: Rachel Duncan, PharmD BCPS

Educational Pearls:

• Toradol (Ketorolac) is an NSAID used for its anti-inflammatory properties
• In practice, the common dosages are 30mg IV or 60mg IM.
• Clinical concerns arise in patients with renal insufficiency or bleeding, but the risks are small (<1%).
• Studies have found that doses over 7.5mg have the same efficacy in pain control as higher doses.
• Consider lower-dose Toradol (15mg) and decrease dose in the elderly and those with a CrCl<50.

References: Motov S, Yasavolian M, Likourezos A, et al. "Comparison of Intravenous Ketorolac at Three Single-Dose Regimens for Treating Acute Pain in the Emergency Department: A Randomized Controlled Trial". Ann Emerg Med 2016. http://www.annemergmed.com/article/S0196-0644(16)31244-6/fulltext