Podcast 551:  PPIs are Not Benign

Podcast 551: PPIs are Not Benign

Contributor: Don Stader, MD

Educational Pearls:

  • PPIs (Proton pump inhibitors) reduce stomach acid levels and are commonly prescribed in patients with GERD or peptic ulcer disease
  • Stopping a PPI after sustained use for a month or longer can lead to withdrawal - causing a rebound indigestion or reflux due to a surge in acid production
  • Long term PPI use has noteworthy side effects including increased incidence of bacterial GI infections and pneumonia
  • Be cautious in prescribing a PPI for over 2 weeks. If continued indigestion control is needed, transition to a H2 blocker or OTC antacids if prolonged treatment is needed.

References

1)Haastrup PF, Thompson W, Søndergaard J, Jarbøl DE (2018) Side effects of long-term proton pump inhibitor use: a review. Basic Clin Pharmacol Toxicol 123(2):114–121. https://doi.org/10.1111/bcpt.13023 Review

2) Helgadottir, H.; Bjornsson, E.S. Problems Associated with Deprescribing of Proton Pump Inhibitors. Int. J. Mol. Sci. 2019, 20, 5469.

Summarized by Jackson Roos, MS3 | Edited by Erik Verzemnieks, MD



Avsnitt(1147)

COVID-19 in the United States: Where are the tests?

COVID-19 in the United States: Where are the tests?

A dive into how the United States responded to an emerging pandemic and the pitfalls along the way that led to stalled testing capacity across the country before community transmission was confirmed. ...

2 Apr 202010min

Husband & Wife, Both ER Clinicians, Share Their Experience Having COVID-19

Husband & Wife, Both ER Clinicians, Share Their Experience Having COVID-19

Long time friends of EMM, Aaron and Bree, share their experiences on the frontlines in the ED, coping with COVID, managing anxiety and quarantining with their family.

1 Apr 202036min

COVID-19 Digest: Do NSAIDs Make COVID-19 More Severe? (Recorded 3/30/20, 18:00 MST)

COVID-19 Digest: Do NSAIDs Make COVID-19 More Severe? (Recorded 3/30/20, 18:00 MST)

In the past two weeks, warnings, questions, and misinformation concerning COVID-19 and NSAID use have been spreading...no pun intended..virally. The pace of this evolving pandemic and the equally quic...

31 Mars 202018min

Podcast 552: PE Management and Risk Stratification

Podcast 552: PE Management and Risk Stratification

Contributor: Dylan Luyten, MD Educational Pearls: After you diagnose a pulmonary embolism (PE) via CT or VQ scan, we need to categorize the PE as massive, sub-massive, or just PE to dictate treatment...

30 Mars 20209min

COVID-19 Digest: If You've Had COVID-19, Can You Get it Again? / Convalescent Serum (Recorded 3/26/20, 18:00 MST)

COVID-19 Digest: If You've Had COVID-19, Can You Get it Again? / Convalescent Serum (Recorded 3/26/20, 18:00 MST)

Host: Elizabeth Esty, MD Research By: Elizabeth Esty and Nathan Novotny References: Osumi M. Questions raised over COVID-19 reinfection after Japanese woman develops illness again. The Japan Times. h...

27 Mars 202010min

ER Doc Infected with COVID-19 Shares Experience

ER Doc Infected with COVID-19 Shares Experience

Recorded 3/26/20

27 Mars 202020min

COVID-19: Hydroxychloroquine & Azithromycin / Anosmia / The Aerosolized vs. Droplet Debate (Recorded 3/24/20, 18:00 MST)

COVID-19: Hydroxychloroquine & Azithromycin / Anosmia / The Aerosolized vs. Droplet Debate (Recorded 3/24/20, 18:00 MST)

The circumstances surrounding the COVID-19 virus are quickly evolving and that means that EMM will have to as well. For the foreseeable future, EMM will be releasing COVID-19 updates. In this series, ...

25 Mars 202015min

Populärt inom Vetenskap

p3-dystopia
dumma-manniskor
svd-nyhetsartiklar
allt-du-velat-veta
kapitalet-en-podd-om-ekonomi
sexet
rss-ufo-bortom-rimligt-tvivel
rss-experimentet
rss-vetenskapsradion-2
hacka-livet
paranormalt-med-caroline-giertz
dumforklarat
medicinvetarna
det-morka-psyket
rss-spraket
4health-med-anna-sparre
halsorevolutionen
rss-vetenskapsradion
pojkmottagningen
rss-tidslinjen-podcast