Podcast 555:  Anticoagulation vs. Antiplatelet

Podcast 555: Anticoagulation vs. Antiplatelet

Contributor: Don Stader, MD

Educational Pearls:

  • When do we give antiplatelet drugs or anti-coagulation drugs?
    • Arterial issues get antiplatelet therapy
    • Venous issues, or slow flow states, get anticoagulation therapy.
  • High flow areas (arteries) are more prone to platelet clotting while the venous system is more prone to allowing blockages caused by coagulation factors.
  • The main side effect with antiplatelet and anticoagulants is bleeding. Typically antiplatelet drugs cause more bleeding issues because platelets are made in the bone marrow, while coagulation factors are made in the liver, so it takes longer for the bone marrow to replete platelets versus the liver which is a fast synthesizer of clotting factors.
  • Reversal of antiplatelet drugs can take a while, so patients on these drugs (ex. Plavix) may need a week of withholding the drug to get surgery, while anti-coagulation drugs (ex. Xarelto) can be stopped a day or two prior to surgery.

References

1. Altiok, E. Marx, N. Oral Anticoagulation: Update on Anticoagulation With Vitamin K Antagonists and Non–Vitamin K–Dependent Oral Anticoagulants. Dtsch Arztebl Int. 2018 Nov; 115(46): 776–783. Published online 2018 Nov 16. doi: 10.3238/arztebl.2018.0776

2. Kapil, N. Et al. Antiplatelet and Anticoagulant Therapies for Prevention of Ischemic Stroke.

Clin Appl Thromb Hemost. 2017 May;23(4):301-318. doi: 10.1177/1076029616660762. Epub 2016 Jul 26.

3. Ostergaard, L. Fosbol EL. Roe MT. The Role of Antiplatelet Therapy in Primary Prevention. A Review. Curr Pharm Des. 2017;23(9):1294-1306. doi: 10.2174/1381612822666161205115540.

Summarized by Jackson Roos, MS3 | Edited by Erik Verzemnieks, MD



Avsnitt(1146)

Podcast 842: "History of Wound Care"

Podcast 842: "History of Wound Care"

Contributor: Chris Holmes, MD Educational Pearls: Through world history, there have been various interesting approaches to wound care Ancient Egyptians applied honey, lint, and grease which provided ...

4 Jan 20234min

Podcast 841: Wound Care

Podcast 841: Wound Care

Contributor: Aaron Lessen, MD Educational Pearls: Wound care in the emergency department aims to prevent future infection Copious wound irrigation is the important step in preventing wound infection ...

3 Jan 20233min

Podcast 840: Abnormal Pediatric Vitals at Discharge

Podcast 840: Abnormal Pediatric Vitals at Discharge

Contributor: Aaron Lessen, MD Educational Pearls: Pediatric patients frequently have vital signs considered abnormal for age at discharge Large multicenter study recently evaluated if pediatric patie...

29 Dec 20223min

Podcast 839: Causes of Pancreatitis

Podcast 839: Causes of Pancreatitis

Contributor: Travis Barlock, MD Educational Pearls: The causes of pancreatitis can be remembered with the mnemonic: "GET SMASHED" G: Gallstones (Most common cause of pancreatitis overall) E: Ethan...

19 Dec 20223min

Podcast 838: Sternoclavicular Septic Arthritis

Podcast 838: Sternoclavicular Septic Arthritis

Contributor: Aaron Lessen, MD Educational Pearls: Septic arthritis of the sternoclavicular joint is uncommon accounting for Immunosuppression and IV drug use increases the risk  Can account for up ...

13 Dec 20224min

Podcast 837: Snakebites

Podcast 837: Snakebites

Contributor: Meghan Hurley, MD Educational Pearls: Venomous snakes in the United States include species from the family Elapidae and subfamily Crotalinae In prehospital setting, elevate the bitten ex...

12 Dec 20226min

Podcast 836: Humming to get EJ

Podcast 836: Humming to get EJ

Contributor: Jared Scott, MD Educational Pearls: Two conventional ways to aid in external jugular vein (EJ) catheter placement are Trendelenburg's position and Valsalva's maneuver by patient One stu...

6 Dec 20223min

Podcast 835: Syncope Review

Podcast 835: Syncope Review

Contributor: Meghan Hurley, MD Educational Pearls: Syncope is defined as a loss of consciousness with an immediate return to baseline Differential is broad Cardiogenic Structural (aortic stenosis, ...

5 Dec 20226min

Populärt inom Vetenskap

dumma-manniskor
svd-nyhetsartiklar
p3-dystopia
allt-du-velat-veta
kapitalet-en-podd-om-ekonomi
det-morka-psyket
rss-ufo-bortom-rimligt-tvivel
rss-vetenskapsradion
pojkmottagningen
sexet
rss-vetenskapsradion-2
dumforklarat
rss-broccolipodden-en-podcast-som-inte-handlar-om-broccoli
medicinvetarna
halsorevolutionen
bildningspodden
rss-experimentet
rss-spraket
hacka-livet
vetenskapsradion