Podcast 637: LSD

Podcast 637: LSD

Contributor: Katie Sprinkel, MD

Educational Pearls:

  • Commonly known as "acid," LSD is seeing a resurgence in the population as a recreational hallucination
  • Onset is about 30 minutes with peak pharmacologic effects at 2-4 hours, the drug's half life is 3 hours resulting in some prolonged effects
  • While there is not an significant addictive component of LSD, tolerance for LSD does occur and prolonged usage is associated with increased incidence of schizophreniform disorders
  • Hallucinations and pseudo-hallucinations (sensory misperceptions) are typical of LSD intoxication, other common signs of intoxication include nausea, diaphoresis, tachycardia, mydriasis, and hypertension
  • More serious effects can be coma, hyperthermia, seizures, cardiac arrest, serotonin syndrome (with concomitant SSRI use) and coagulopathy, although the dose to cause these effects is very high
  • Treatment is decreasing sensory stimulation, benzodiazepines in some cases, and symptomatic treatment - no specific antidote exists

References

Blaho K, Merigian K, Winbery S, Geraci SA, Smartt C. Clinical pharmacology of lysergic acid diethylamide: case reports and review of the treatment of intoxication. Am J Ther. 1997 May-Jun;4(5-6):211-21. doi: 10.1097/00045391-199705000-00008. PMID: 10423613.

Klock JC, Boerner U, Becker CE. Coma, hyperthermia and bleeding associated with massive LSD overdose. A report of eight cases. West J Med. 1974;120(3):183-188.

Summarized by John Spartz, MS3 | Edited by Erik Verzemnieks, MD



Avsnitt(1147)

Mental Health Monthly #5: Borderline Personality Disorder

Mental Health Monthly #5: Borderline Personality Disorder

For this episode of Mental Health Monthly, EMM is honored to collaborate with the hosts of Millennial Mental Health Channel podcast to explain Borderline Personality Disorder and tips to manage patien...

25 Nov 202018min

Podcast 616: MDIs for the Win

Podcast 616: MDIs for the Win

Contributor: Aaron Lessen, MD Educational Pearls: Contrary to many assumptions, meter-dose inhalers (MDIs) are as effective as nebulizers in pediatric and adult patients Nebulizers are associated wit...

24 Nov 20203min

Podcast 615: Pediatric DKA

Podcast 615: Pediatric DKA

Contributor: Ryan Circh, MD Educational Pearls: Diabetic ketoacidosis (DKA) can be the initial presenting condition of undiagnosed diabetes type I in pediatric patients Unlike adults, children typica...

23 Nov 20205min

Podcast 614: Perichondritis

Podcast 614: Perichondritis

Contributor: Nick Tsipis, MD Educational Pearls: Perichondritis involves infection of not only the connective tissue of the ear but typically the cartilage as well Symptoms include erythema, ear pain...

17 Nov 20204min

Podcast 613: Spontaneous Bacterial Peritonitis

Podcast 613: Spontaneous Bacterial Peritonitis

Contributor: Sam Killian, MD Educational Pearls: Spontaneous bacterial peritonitis (SBP) is an infection of peritoneal fluid that typically occurs in cirrhotic patients Symptoms may include abdominal...

16 Nov 20204min

Pharmacy Phriday #3: Drug Shortages in COVID

Pharmacy Phriday #3: Drug Shortages in COVID

Contributor: Rachael Waterson, PharmD Educational Pearls: Drug shortages have been an ongoing issue since the 2000's. Improvement was being made; however, several factors have exacerbated the drug s...

13 Nov 202016min

UnfilterED #11: Dr. Ricky Dhaliwal

UnfilterED #11: Dr. Ricky Dhaliwal

Dr. Tsipis sits down with colleague Dr. Ricky Dhaliwal for some insightful conversation regarding the differences between academic and community settings as well as the various roles of advocacy in me...

11 Nov 202040min

Podcast 612: Origin of Vaccines

Podcast 612: Origin of Vaccines

Contributor: Dave Rosenberg, MD Educational Pearls: The potential of vaccinations was first observed in the late 1600s when Jenner observed people who had cowpox never contracted smallpox, so he inoc...

10 Nov 20204min

Populärt inom Vetenskap

p3-dystopia
dumma-manniskor
svd-nyhetsartiklar
allt-du-velat-veta
kapitalet-en-podd-om-ekonomi
rss-vetenskapsradion
rss-ufo-bortom-rimligt-tvivel
medicinvetarna
rss-vetenskapsradion-2
rss-experimentet
det-morka-psyket
sexet
rss-spraket
hacka-livet
dumforklarat
pojkmottagningen
rss-personlighetspodden
rss-arkeologi-historia-podden-som-graver-i-vart-kulturlandskap
paranormalt-med-caroline-giertz
halsorevolutionen